Houcemeddine Othman
Houcemeddine Othman
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In silico study of the spike protein from SARS-CoV-2 interaction with ACE2: similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism
H Othman, Z Bouslama, JT Brandenburg, J Da Rocha, Y Hamdi, ...
BioRxiv, 2020
The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells
I Riahi-Chebbi, S Souid, H Othman, M Haoues, H Karoui, A Morel, ...
Scientific Reports 9 (1), 195, 2019
Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor‐induced angiogenesis through cell cycle arrest, apoptosis induction and …
O Zakraoui, C Marcinkiewicz, Z Aloui, H Othman, R Grépin, M Haoues, ...
Molecular carcinogenesis, 2016
PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells
M Morjen, O Kallech-Ziri, A Bazaa, H Othman, K Mabrouk, ...
Matrix Biology 32 (1), 52-62, 2013
Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells
C Ellijimi, MB Hammouda, H Othman, W Moslah, J Jebali, HB Mabrouk, ...
Biomedicine & Pharmacotherapy 101, 871-880, 2018
Functional role of Kv1. 1 and Kv1. 3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides
D Aissaoui, S Mlayah-Bellalouna, J Jebali, Z Abdelkafi-Koubaa, S Souid, ...
International journal of biological macromolecules 111, 1146-1155, 2018
Two distinct conformational states of Mycobacterium tuberculosis virulent factor ESAT-6 are behind the discrepancy around its biological functions
A Refai, M Haoues, H Othman, MR Barbouche, P Moua, A Bondon, ...
FEBS Journal, In press, 2015
A review of clinical pharmacogenetics Studies in African populations
F Radouani, L Zass, Y Hamdi, J Rocha, R Sallam, S Abdelhak, S Ahmed, ...
Personalized Medicine 17 (2), 155-170, 2020
Anti-tumoral effect of scorpion peptides: emerging new cellular targets and signaling pathways
N Srairi-Abid, H Othman, D Aissaoui, R BenAissa
Cell Calcium, 2019
Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances …
MB Hammouda, I Riahi-Chebbi, S Souid, H Othman, Z Aloui, N Srairi-Abid, ...
Biochimica et Biophysica Acta (BBA)-General Subjects, 2017
A thermoactive L-amino acid oxidase from Cerastes cerastes snake venom: Purification, biochemical and molecular characterization
Z Abdelkafi-Koubaa, J Jebali, H Othman, M Morjen, I Aissa, ...
Toxicon 89, 32-44, 2014
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of possible putative protective effect
S Haddad-Boubaker, H Othman, R Touati, K Ayouni, M Lakhal, ...
The extent and impact of variation in ADME genes in sub-Saharan African populations
J da Rocha, H Othman, G Botha, D Twesigomwe, S Ahmed, L Cottino, ...
bioRxiv, 2020
SARS-CoV-2 spike protein unlikely to bind to integrins via the Arg-Gly-Asp (RGD) motif of the Receptor Binding Domain: evidence from structural analysis and microscale …
H Othman, HB Messaoud, O Khamessi, HB Mabrouk, K Ghedira, ...
bioRxiv, 2021
In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion
H Othman, SA Wieninger, M ElAyeb, M Nilges, N Srairi-Abid
Journal of Biomolecular Structure and Dynamics, 1-15, 2016
The galactolipase activity of Fusarium solani (phospho) lipase
R Jallouli, H Othman, S Amara, G Parsiegla, F Carriere, N Srairi-abid, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015
Human OMICs and Computational Biology Research in Africa: Current Challenges and Prospects
Y Hamdi, L Zass, H Othman, F Radouani, I Allali, M Hanachi, CJ Okeke, ...
OMICS: A Journal of Integrative Biology, 2021
Identification of novel BRCA1 and RAD50 mutations associated with breast cancer predisposition in Tunisian patients
N Mighri, Y Hamdi, M Boujemaa, H Othman, SB Nasr, H El Benna, N Mejri, ...
Frontiers in Genetics 11, 1397, 2020
G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19
JEB da Rocha, H Othman, CT Tiemessen, G Botha, M Ramsay, ...
The Pharmacogenomics Journal, 1-8, 2021
AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells
R BenAissa, H Othman, C Villard, S Peigneur, S Mlayah-Bellalouna, ...
Biochemical and biophysical research communications 521 (2), 340-346, 2020
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