| TET enzymes, TDG and the dynamics of DNA demethylation RM Kohli, Y Zhang Nature 502 (7472), 472-479, 2013 | 1788 | 2013 |
| Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells JA Fraietta, CL Nobles, MA Sammons, S Lundh, SA Carty, TJ Reich, ... Nature 558 (7709), 307-312, 2018 | 690 | 2018 |
| Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase JW Trauger, RM Kohli, HD Mootz, MA Marahiel, CT Walsh Nature 407 (6801), 215-218, 2000 | 405 | 2000 |
| Biomimetic synthesis and optimization of cyclic peptide antibiotics RM Kohli, CT Walsh, MD Burkart Nature 418 (6898), 658-661, 2002 | 387 | 2002 |
| AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation CS Nabel, H Jia, Y Ye, L Shen, HL Goldschmidt, JT Stivers, Y Zhang, ... Nature chemical biology 8 (9), 751-758, 2012 | 370 | 2012 |
| Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE SD Bruner, T Weber, RM Kohli, D Schwarzer, MA Marahiel, CT Walsh, ... Structure 10 (3), 301-310, 2002 | 320 | 2002 |
| The oxidative half-reaction of old yellow enzyme: The role of tyrosine 196 RM Kohli, V Massey Journal of biological chemistry 273 (49), 32763-32770, 1998 | 266 | 1998 |
| Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases RM Kohli, JW Trauger, D Schwarzer, MA Marahiel, CT Walsh Biochemistry 40 (24), 7099-7108, 2001 | 248 | 2001 |
| The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential CS Nabel, SA Manning, RM Kohli ACS chemical biology 7 (1), 20-30, 2012 | 203 | 2012 |
| Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase EK Schutsky, JE DeNizio, P Hu, MY Liu, CS Nabel, EB Fabyanic, ... Nature biotechnology 36 (11), 1083-1090, 2018 | 181 | 2018 |
| A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase RM Kohli, SR Abrams, KS Gajula, RW Maul, PJ Gearhart, JT Stivers Journal of biological chemistry 284 (34), 22898-22904, 2009 | 168 | 2009 |
| Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase CC Tseng, SD Bruner, RM Kohli, MA Marahiel, CT Walsh, SA Sieber Biochemistry 41 (45), 13350-13359, 2002 | 162 | 2002 |
| Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase JW Trauger, RM Kohli, CT Walsh Biochemistry 40 (24), 7092-7098, 2001 | 156 | 2001 |
| Type II thioesterase restores activity of a NRPS module stalled with an aminoacyl‐S‐enzyme that cannot be elongated E Yeh, RM Kohli, SD Bruner, CT Walsh ChemBioChem 5 (9), 1290-1293, 2004 | 151 | 2004 |
| Targets for combating the evolution of acquired antibiotic resistance MJ Culyba, CY Mo, RM Kohli Biochemistry 54 (23), 3573-3582, 2015 | 145 | 2015 |
| Enzymology of acyl chain macrocyclization in natural product biosynthesis RM Kohli, CT Walsh Chemical Communications, 297-307, 2003 | 144 | 2003 |
| Chain Termination Steps in Nonribosomal Peptide Synthetase Assembly Lines: Directed Acyl‐S‐Enzyme Breakdown in Antibiotic and Siderophore Biosynthesis TA Keating, DE Ehmann, RM Kohli, CG Marshall, JW Trauger, CT Walsh ChemBioChem 2 (2), 99-107, 2001 | 144 | 2001 |
| Timing of epimerization and condensation reactions in nonribosomal peptide assembly lines: kinetic analysis of phenylalanine activating elongation modules of tyrocidine … L Luo, RM Kohli, M Onishi, U Linne, MA Marahiel, CT Walsh Biochemistry 41 (29), 9184-9196, 2002 | 129 | 2002 |
| The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation MA McMahon, JD Siliciano, J Lai, JO Liu, JT Stivers, RF Siliciano, ... Journal of biological chemistry 283 (46), 31289-31293, 2008 | 107 | 2008 |
| The role of threonine 37 in flavin reactivity of the old yellow enzyme D Xu, RM Kohli, V Massey Proceedings of the National Academy of Sciences 96 (7), 3556-3561, 1999 | 107 | 1999 |
