ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence RL McPherson, R Abraham, E Sreekumar, SE Ong, SJ Cheng, VK Baxter, ... Proceedings of the National Academy of Sciences 114 (7), 1666-1671, 2017 | 170 | 2017 |
ADP-ribosyl–binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication R Abraham, D Hauer, RL McPherson, A Utt, IT Kirby, MS Cohen, A Merits, ... Proceedings of the National Academy of Sciences 115 (44), E10457-E10466, 2018 | 119 | 2018 |
ENPP1 processes protein ADP‐ribosylation in vitro L Palazzo, CM Daniels, JE Nettleship, N Rahman, RL McPherson, ... The FEBS journal 283 (18), 3371-3388, 2016 | 74 | 2016 |
ELTA: enzymatic labeling of terminal ADP-ribose Y Ando, E Elkayam, RL McPherson, M Dasovich, SJ Cheng, J Voorneveld, ... Molecular cell 73 (4), 845-856. e5, 2019 | 54 | 2019 |
Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases AKL Leung, RL McPherson, DE Griffin PLoS pathogens 14 (3), e1006864, 2018 | 51 | 2018 |
Both ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain affect neurovirulence in mice R Abraham, RL McPherson, M Dasovich, M Badiee, AKL Leung, ... MBio 11 (1), 10.1128/mbio. 03253-19, 2020 | 43 | 2020 |
High-throughput activity assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain M Dasovich, J Zhuo, JA Goodman, A Thomas, RL McPherson, ... ACS chemical biology 17 (1), 17-23, 2021 | 30 | 2021 |
Structural analyses of NudT16–ADP-ribose complexes direct rational design of mutants with improved processing of poly (ADP-ribosyl) ated proteins P Thirawatananond, RL McPherson, J Malhi, S Nathan, MJ Lambrecht, ... Scientific reports 9 (1), 5940, 2019 | 17 | 2019 |
ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4 RG Hammond, N Schormann, RL McPherson, AKL Leung, ... Proceedings of the National Academy of Sciences 118 (2), e2004500118, 2021 | 6 | 2021 |
Human oral lectin ZG16B acts as a cell wall polysaccharide probe to decode host–microbe interactions with oral commensals S Ghosh, CP Ahearn, CR Isabella, VM Marando, GJ Dodge, H Bartlett, ... Proceedings of the National Academy of Sciences 120 (22), e2216304120, 2023 | 4 | 2023 |
Lectin-Seq: a method to profile lectin-microbe interactions in native communities RL McPherson, CR Isabella, RL Walker, D Sergio, S Bae, T Gaca, ... Science Advances 9 (30), eadd8766, 2023 | 3 | 2023 |
Ion-pairing with triethylammonium acetate improves solid-phase extraction of ADP-ribosylated peptides RL McPherson, SE Ong, AKL Leung Journal of proteome research 19 (2), 984-990, 2019 | 3 | 2019 |
Application of human oral lectin ZG16B as a microbial glycan analysis probe (mGAP) to decode host-microbe interactions S Ghosh, C Ahearn, C Isabella, V Marando, G Dodge, R McPherson, ... Journal of Biological Chemistry 299 (3), S389, 2023 | | 2023 |
Application of human oral lectin ZG16B as a microbial glycan analysis probe (mGAP) to decode host-microbe interactions S Ghosh, CP Ahearn, CR Isabella, VM Marando, GJ Dodge, H Bartlett, ... GLYCOBIOLOGY 32 (11), 1043-1043, 2022 | | 2022 |
Methods and uses of enzymatic labeling of adp-ribose containing molecules AKL Leung, Y Ando, RL McPherson, M Badiee, E Elkayam US Patent App. 17/044,913, 2021 | | 2021 |
High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain (preprint) MA Dasovich, J Zhou, AG Thomas, JA Goodman, RL McPherson, ... | | 2021 |
Biochemical and proteomic investigations on the role of ADP-ribosylation in viral infection RL McPherson Johns Hopkins University, 2019 | | 2019 |
Preparation of recombinant Alphaviruses for functional studies of ADP-ribosylation R Abraham, RL McPherson, E Sreekumar, AKL Leung, DE Griffin ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols, 297-316, 2018 | | 2018 |
Quantitative determination of MAR hydrolase residue specificity in vitro by tandem mass spectrometry RL McPherson, SE Ong, AKL Leung ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols, 271-283, 2018 | | 2018 |
Protein engineering of the decapping enzyme NudT16 enhances its ability to hydrolyze protein-conjugated ADP-ribose for post-translational site identification via mass spectrometry P Thirawatananond, RL McPherson, JK Malhi, AK Leung, SB Gabelli Cancer Research 77 (13_Supplement), 2212-2212, 2017 | | 2017 |