FLICE, a novel FADD-homologous ICE/CED-3–like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex M Muzio, AM Chinnaiyan, FC Kischkel, K O'Rourke, A Shevchenko, J Ni, ... Cell 85 (6), 817-827, 1996 | 3968 | 1996 |
An induced proximity model for caspase-8 activation M Muzio, BR Stockwell, HR Stennicke, GS Salvesen, VM Dixit Journal of Biological Chemistry 273 (5), 2926-2930, 1998 | 1574 | 1998 |
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells M Muzio, D Bosisio, N Polentarutti, G D’amico, A Stoppacciaro, ... The Journal of Immunology 164 (11), 5998-6004, 2000 | 1572 | 2000 |
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling M Muzio, J Ni, P Feng, VM Dixit Science 278 (5343), 1612-1615, 1997 | 1491 | 1997 |
Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4 F Colotta, F Re, M Muzio, R Bertini, N Polentarutti, M Sironi, JG Giri, ... Science 261 (5120), 472-475, 1993 | 1291 | 1993 |
The human Toll signaling pathway: divergence of nuclear factor κB and JNK/SAPK activation upstream of tumor necrosis factor receptor–associated factor 6 (TRAF6) M Muzio, G Natoli, S Saccani, M Levrero, A Mantovani Journal of Experimental Medicine 187 (12), 2097-2101, 1998 | 791 | 1998 |
Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes FX Zhang, CJ Kirschning, R Mancinelli, XP Xu, Y Jin, E Faure, ... Journal of Biological Chemistry 274 (12), 7611-7614, 1999 | 770 | 1999 |
Bacterial lipopolysaccharide activates NF-κB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells differential expression of TLR-4 and TLR-2 in … E Faure, O Equils, PA Sieling, L Thomas, FX Zhang, CJ Kirschning, ... Journal of Biological Chemistry 275 (15), 11058-11063, 2000 | 737 | 2000 |
Target protease specificity of the viral serpin CrmA Analysis of five caspases Q Zhou, S Snipas, K Orth, M Muzio, VM Dixit, GS Salvesen Journal of Biological Chemistry 272 (12), 7797-7800, 1997 | 688 | 1997 |
Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c T Kuwana, JJ Smith, M Muzio, V Dixit, DD Newmeyer, S Kornbluth Journal of Biological Chemistry 273 (26), 16589-16594, 1998 | 498 | 1998 |
FLICE induced apoptosis in a cell-free system cleavage of caspase zymogens M Muzio, GS Salvesen, VM Dixit Journal of Biological Chemistry 272 (5), 2952-2956, 1997 | 480 | 1997 |
Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-γ: a molecular basis for priming and synergism with bacterial lipopolysaccharide D Bosisio, N Polentarutti, M Sironi, S Bernasconi, K Miyake, GR Webb, ... Blood 99 (9), 3427-3431, 2002 | 370 | 2002 |
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family C Garlanda, F Riva, N Polentarutti, C Buracchi, M Sironi, M De Bortoli, ... Proceedings of the National Academy of Sciences 101 (10), 3522-3526, 2004 | 309 | 2004 |
Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy M Muzio, B Apollonio, C Scielzo, M Frenquelli, I Vandoni, V Boussiotis, ... Blood 112 (1), 188-195, 2008 | 293 | 2008 |
Toll-like receptor family and signalling pathway M Muzio, N Polentarutti, D Bosisio, PPM Kumar, A Mantovani Biochemical society transactions 28 (5), 563-566, 2000 | 273 | 2000 |
Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes. M Muzio, N Polentarutti, D Bosisio, MK Prahladan, A Mantovani Journal of leukocyte biology 67 (4), 450-456, 2000 | 245 | 2000 |
The type II" receptor" as a decoy target for interleukin 1 in polymorphonuclear leukocytes: characterization of induction by dexamethasone and ligand binding properties of the … F Re, M Muzio, M De Rossi, N Polentarutti, JG Giri, A Mantovani, F Colotta Journal of Experimental Medicine 179 (2), 739-743, 1994 | 241 | 1994 |
Micrococci and peptidoglycan activate TLR2→ MyD88→ IRAK→ TRAF→ NIK→ IKK→ NF-κB signal transduction pathway that induces transcription of interleukin-8 Q Wang, R Dziarski, CJ Kirschning, M Muzio, D Gupta Infection and immunity 69 (4), 2270-2276, 2001 | 232 | 2001 |
Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist. M Muzio, N Polentarutti, M Sironi, G Poli, L De Gioia, M Introna, ... Journal of Experimental Medicine 182 (2), 623-628, 1995 | 185 | 1995 |
Expression and function of toll like receptors in chronic lymphocytic leukaemia cells M Muzio, C Scielzo, MTS Bertilaccio, M Frenquelli, P Ghia, ... British journal of haematology 144 (4), 507-516, 2009 | 164 | 2009 |