| The therapeutic potential of chemical chaperones in protein folding diseases L Cortez, V Sim Prion 8 (2), 197-202, 2014 | 253 | 2014 |
| Bile acids reduce prion conversion, reduce neuronal loss, and prolong male survival in models of prion disease LM Cortez, J Campeau, G Norman, M Kalayil, J Van der Merwe, ... Journal of virology 89 (15), 7660-7672, 2015 | 68 | 2015 |
| Early stages of aggregation of engineered α-synuclein monomers and oligomers in solution X Li, C Dong, M Hoffmann, CR Garen, LM Cortez, NO Petersen, ... Scientific Reports 9 (1), 1734, 2019 | 54 | 2019 |
| Pharmacological chaperone reshapes the energy landscape for folding and aggregation of the prion protein AN Gupta, K Neupane, N Rezajooei, LM Cortez, VL Sim, MT Woodside Nature Communications 7 (1), 12058, 2016 | 47 | 2016 |
| Aggregation state and neurotoxic properties of alzheimer β-amyloid peptide A Mohamed, L Cortez, E Posse de Chaves Current Protein and Peptide Science 12 (3), 235-257, 2011 | 35 | 2011 |
| Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in α-synuclein aggregation CM Torres-Bugeau, CL Ávila, R Raisman-Vozari, D Papy-Garcia, R Itri, ... Journal of Biological Chemistry 287 (4), 2398-2409, 2012 | 33 | 2012 |
| Toll‐like receptor‐mediated immune response inhibits prion propagation SG Kang, C Kim, LM Cortez, M Carmen Garza, J Yang, H Wille, VL Sim, ... Glia 64 (6), 937-951, 2016 | 22 | 2016 |
| Mouse prion protein polymorphism Phe-108/Val-189 affects the kinetics of fibril formation and the response to seeding: evidence for a two-step nucleation polymerization mechanism LM Cortez, J Kumar, L Renault, HS Young, VL Sim Journal of Biological Chemistry 288 (7), 4772-4781, 2013 | 18 | 2013 |
| Native nanodiscs formed by styrene maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids M Esmaili, BP Tancowny, X Wang, A Moses, LM Cortez, VL Sim, H Wille, ... Journal of Biological Chemistry 295 (25), 8460-8469, 2020 | 15 | 2020 |
| Asymmetric-flow field-flow fractionation of prions reveals a strain-specific continuum of quaternary structures with protease resistance developing at a hydrodynamic radius of … LM Cortez, SK Nemani, C Duque Velásquez, A Sriraman, YL Wang, ... PLoS Pathogens 17 (6), e1009703, 2021 | 14 | 2021 |
| Implications of prion polymorphisms LM Cortez, VL Sim Prion 7 (4), 276-279, 2013 | 14 | 2013 |
| Implications of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology Q Wu, L Cortez, R Kamali-Jamil, V Sim, H Wille, S Kar Disease Models & Mechanisms 14 (10), dmm048929, 2021 | 13 | 2021 |
| Quaternary Structure Changes for PrPSc Predate PrPC Downregulation and Neuronal Death During Progression of Experimental Scrapie Disease G Eskandari-Sedighi, LM Cortez, J Yang, N Daude, K Shmeit, V Sim, ... Molecular Neurobiology 58 (1), 375-390, 2021 | 11 | 2021 |
| Redox-active tyrosine residue in the microcin J25 molecule MC Chalón, N Wilke, J Pedersen, S Rufini, RD Morero, L Cortez, ... Biochemical and Biophysical Research Communications 406 (3), 366-370, 2011 | 11 | 2011 |
| Glyceraldehyde-3-phosphate dehydrogenase tetramer dissociation and amyloid fibril formation induced by negatively charged membranes LM Cortez, CL Ávila, CMT Bugeau, RN Farías, RD Morero, RN Chehín FEBS letters 584 (3), 625-630, 2010 | 11 | 2010 |
| Interactions between α-conotoxin MI and the Torpedo marmorata receptor α–δ interface L Cortez, C Marino-Buslje, MB de Jiménez Bonino, U Hellman Biochemical and biophysical research communications 355 (1), 275-279, 2007 | 9 | 2007 |
| Conotoxin MI inhibits the α–δ acetylcholine binding site of the Torpedo marmorata receptor LM Cortez, SG del Canto, FD Testai, MJB de Jiménez Bonino Biochemical and biophysical research communications 295 (4), 791-795, 2002 | 6 | 2002 |
| The therapeutic potential of chemical chaperones in protein folding diseases. Prion 8: 197–202 L Cortez, V Sim | 5 | 2014 |
| Distinctive toll-like receptors gene expression and glial response in different brain regions of natural Scrapie M García-Martínez, LM Cortez, A Otero, M Betancor, B Serrano-Pérez, ... International Journal of Molecular Sciences 23 (7), 3579, 2022 | 4 | 2022 |
| Probing the origin of prion protein misfolding via reconstruction of ancestral proteins LM Cortez, AJ Morrison, CR Garen, S Patterson, T Uyesugi, R Petrosyan, ... Protein Science 31 (12), e4477, 2022 | 3 | 2022 |
Valerie SimUniversity of AlbertaVerified email at ualberta.ca
