Mohamed Uduman
Mohamed Uduman
Director, Immuno-Oncology Computational Biology, Dana-Farber Cancer Institute
Verified email at
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Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data
NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ...
Bioinformatics 31 (20), 3356-3358, 2015
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires
JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’connor, ...
Bioinformatics 30 (13), 1930-1932, 2014
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma
Z Hu, DE Leet, RL Allesøe, G Oliveira, S Li, AM Luoma, J Liu, J Forman, ...
Nature medicine 27 (3), 515-525, 2021
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data
G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ...
Frontiers in immunology 4, 358, 2013
Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles
D Gadala-Maria, G Yaari, M Uduman, SH Kleinstein
Proceedings of the National Academy of Sciences 112 (8), E862-E870, 2015
An atlas of substrate specificities for the human serine/threonine kinome
JL Johnson, TM Yaron, EM Huntsman, A Kerelsky, J Song, A Regev, ...
Nature 613 (7945), 759-766, 2023
Quantifying selection in high-throughput Immunoglobulin sequencing data sets
G Yaari, M Uduman, SH Kleinstein
Nucleic acids research 40 (17), e134-e134, 2012
High-resolution antibody dynamics of vaccine-induced immune responses
U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ...
Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014
Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution
V Florou, AE Rosenberg, E Wieder, KV Komanduri, D Kolonias, ...
Journal for immunotherapy of cancer 7, 1-8, 2019
Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells
SM Anderson, A Khalil, M Uduman, U Hershberg, Y Louzoun, ...
The Journal of Immunology 183 (11), 7314-7325, 2009
Mutation-derived neoantigens for cancer immunotherapy
JC Castle, M Uduman, S Pabla, RB Stein, JS Buell
Frontiers in immunology 10, 1856, 2019
Improved methods for detecting selection by mutation analysis of Ig V region sequences
U Hershberg, M Uduman, MJ Shlomchik, SH Kleinstein
International immunology 20 (5), 683-694, 2008
Detecting selection in immunoglobulin sequences
M Uduman, G Yaari, U Hershberg, JA Stern, MJ Shlomchik, SH Kleinstein
Nucleic acids research 39 (suppl_2), W499-W504, 2011
Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue
Y Zhao, M Uduman, JHY Siu, TJ Tull, JD Sanderson, YCB Wu, JQ Zhou, ...
Nature communications 9 (1), 3857, 2018
Cell subset prediction for blood genomic studies
CR Bolen, M Uduman, SH Kleinstein
BMC bioinformatics 12, 1-10, 2011
Shared VH1-46 gene usage by pemphigus vulgaris autoantibodies indicates common humoral immune responses among patients
MJ Cho, ASY Lo, X Mao, AR Nagler, CT Ellebrecht, EM Mukherjee, ...
Nature communications 5 (1), 4167, 2014
Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis
YCB Wu, LK James, JA Vander Heiden, M Uduman, SR Durham, ...
Journal of allergy and clinical immunology 134 (3), 604-612, 2014
A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation
G Lazarian, S Yin, E Ten Hacken, T Sewastianik, M Uduman, A Font-Tello, ...
Cancer Cell 39 (3), 380-393. e8, 2021
Integrating B cell lineage information into statistical tests for detecting selection in Ig sequences
M Uduman, MJ Shlomchik, F Vigneault, GM Church, SH Kleinstein
The Journal of Immunology 192 (3), 867-874, 2014
Characterization of diabetogenic CD8+ T cells: immune therapy with metabolic blockade
JW Garyu, M Uduman, A Stewart, J Rui, S Deng, J Shenson, MM Staron, ...
Journal of Biological Chemistry 291 (21), 11230-11240, 2016
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