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Fernando Ugarte
Fernando Ugarte
Verified email at merck.com
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Year
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
J Flach, ST Bakker, M Mohrin, PC Conroy, EM Pietras, D Reynaud, ...
Nature 512 (7513), 198-202, 2014
5102014
Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches
S Smith-Berdan, A Nguyen, D Hassanein, M Zimmer, F Ugarte, J Ciriza, ...
Cell stem cell 8 (1), 72-83, 2011
1412011
Notch signaling enhances osteogenic differentiation while inhibiting adipogenesis in primary human bone marrow stromal cells
F Ugarte, M Ryser, S Thieme, FA Fierro, K Navratiel, M Bornhäuser, ...
Experimental hematology 37 (7), 867-875. e1, 2009
1222009
S1P1 overexpression stimulates S1P-dependent chemotaxis of human CD34+ hematopoietic progenitor cells but strongly inhibits SDF-1/CXCR4-dependent migration and in vivo homing
MF Ryser, F Ugarte, R Lehmann, M Bornhäuser, S Brenner
Molecular immunology 46 (1), 166-171, 2008
1092008
Progressive chromatin condensation and H3K9 methylation regulate the differentiation of embryonic and hematopoietic stem cells
F Ugarte, R Sousae, B Cinquin, EW Martin, J Krietsch, G Sanchez, ...
Stem cell reports 5 (5), 728-740, 2015
1002015
Haematopoietic stem cell niches: new insights inspire new questions
F Ugarte, EC Forsberg
The EMBO journal 32 (19), 2535-2547, 2013
792013
Impact of CXCR4 inhibition on FLT3-ITD− positive human AML blasts
A Jacobi, S Thieme, R Lehmann, F Ugarte, HL Malech, S Koch, C Thiede, ...
Experimental hematology 38 (3), 180-190, 2010
422010
Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and …
S Stopp, M Bornhäuser, F Ugarte, M Wobus, M Kuhn, S Brenner, ...
Haematologica 98 (4), 505, 2013
382013
mRNA transfection of CXCR4-GFP fusion—simply generated by PCR—results in efficient migration of primary human mesenchymal stem cells
MF Ryser, F Ugarte, S Thieme, M Bornhäuser, A Roesen-Wolff, S Brenner
Tissue Engineering Part C: Methods 14 (3), 179-184, 2008
382008
Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape
C Farhy, S Hariharan, J Ylanko, L Orozco, FY Zeng, I Pass, F Ugarte, ...
Elife 8, e49683, 2019
122019
Dinaciclib induces immunogenic cell death and enhances anti-PD-1 mediated tumor suppression
DMS Hossain, F Ugarte, A Sawant, M Cai, V Sriram, E Pinheiro, ...
Cancer Research 76 (14_Supplement), 562-562, 2016
32016
Multiparametric Signature of Glioblastoma Differentiation Revealed by Imaging of Cellular Epigenetic Landscapes
C Farhy, S Hariharan, J Ylanko, L van Woudenberg, F Cimadamore, ...
bioRxiv, 348888, 2018
22018
Histone H3 Phosphorylation in Human Skin Histoculture as a Tool to Evaluate Patient's Response to Antiproliferative Drugs
F Ugarte, K Porth, S Sadekova
Biomarker insights 10, BMI. S29515, 2015
12015
Role of Jagged/Notch Signaling in the Cell Fate Determination of Bone Marrow Human Mesenchymal Stem Cells.
F Ugarte, MF Ryser, S Thieme, M Bornhaeuser, S Brenner
Blood, The Journal of the American Society of Hematology 110 (11), 1923-1923, 2007
12007
514. mRNA Transfection Results in Efficient Overexpression of Transgenes in Leukemic Cell Lines and Hematopoietic Stem Cells
MF Ryser, M Gentsch, F Ugarte, HL Malech, S Brenner
Molecular Therapy 13, S198, 2006
12006
EXPANSION OF HEMATOPOIETIC PROGENITOR CELLS BY HISTONE METHYLTRANSFERASE G9a INHIBITION
F Ugarte
US Patent App. 14/773,114, 2016
2016
Progressive chromatin condensation and H3K9 methylation regulate the differentiation of embryonic and hematopoietic stem cells
C Larabell, F Ugarte, R Sousae, B Cinquin, EW Martin, J Krietsch, ...
2015
MCAM/CD146 expression on human mesenchymal stromal cells influences proliferation and maintenance of hematopoietic stem and progenitor cells during ex vivo expansion
S Stopp, F Ugarte, M Bornhaeuser, S Brenner, S Thieme
ONKOLOGIE 34, 245-245, 2011
2011
Downregulation of MCAM/CD146 in human mesenchymal stromal cells reduces hematopoietic progenitor cell potential
S Thieme, S Stopp, F Ugarte, M Wobus, M Bornhaeuser, S Brenner
HUMAN GENE THERAPY 21 (10), 1480-1480, 2010
2010
NOTCH REGULATES THE EXPRESSION OF MCAM/CD146 IN HUMAN MESENCHYMAL STEM CELLS
S Thieme, F Ugarte, F Fierro, M Bornhaeuser, S Brenner
EXPERIMENTAL HEMATOLOGY 37 (9), S63-S63, 2009
2009
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