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Alvina G Lai
Alvina G Lai
University College London | Associate Professor
Verified email at ucl.ac.uk - Homepage
Title
Cited by
Cited by
Year
CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses
AG Lai, CJ Doherty, B Mueller-Roeber, SA Kay, JHM Schippers, ...
Proceedings of the National Academy of Sciences 109 (42), 17129-17134, 2012
3412012
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer …
AG Lai, L Pasea, A Banerjee, G Hall, S Denaxas, WH Chang, M Katsoulis, ...
BMJ open 10 (11), e043828, 2020
2352020
Estimating excess mortality in people with cancer and multimorbidity in the COVID-19 emergency
AG Lai, L Pasea, A Banerjee, S Denaxas, M Katsoulis, WH Chang, ...
MedRxiv, 2020.05. 27.20083287, 2020
1772020
The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion
D Kao, AG Lai, E Stamataki, S Rosic, N Konstantinides, E Jarvis, ...
elife 5, e20062, 2016
1482016
Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic
A Banerjee, S Chen, L Pasea, AG Lai, M Katsoulis, S Denaxas, V Nafilyan, ...
European journal of preventive cardiology 28 (14), 1599-1609, 2021
1002021
Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource
A Wood, R Denholm, S Hollings, J Cooper, S Ip, V Walker, S Denaxas, ...
bmj 373, 2021
812021
EvoRegen in animals: time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes
AG Lai, AA Aboobaker
Developmental biology 433 (2), 118-131, 2018
682018
The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
X Zhuang, A Magri, M Hill, AG Lai, A Kumar, SB Rambhatla, CL Donald, ...
Nature communications 10 (1), 377, 2019
612019
Interplay between circadian clock and viral infection
X Zhuang, SB Rambhatla, AG Lai, JA McKeating
Journal of Molecular Medicine 95, 1283-1289, 2017
582017
Comparative genomic analysis of innate immunity reveals novel and conserved components in crustacean food crop species
AG Lai, AA Aboobaker
BMC genomics 18 (1), 1-26, 2017
502017
Obesity during the COVID-19 pandemic: both cause of high risk and potential effect of lockdown? A population-based electronic health record study
M Katsoulis, L Pasea, AG Lai, RJB Dobson, S Denaxas, H Hemingway, ...
Public Health 191, 41-47, 2021
442021
The pan‐cancer mutational landscape of the PPAR pathway reveals universal patterns of dysregulated metabolism and interactions with tumor immunity and hypoxia
WH Chang, AG Lai
Annals of the New York Academy of Sciences 1448 (1), 65-82, 2019
422019
Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance
WH Chang, D Forde, AG Lai
Cancer Communications 39 (1), 1-14, 2019
392019
A novel signature derived from immunoregulatory and hypoxia genes predicts prognosis in liver and five other cancers
WH Chang, D Forde, AG Lai
Journal of translational medicine 17 (1), 1-12, 2019
382019
Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with hypoxia and immunoevasion
WH Chang, AG Lai
British journal of cancer 121 (8), 666-678, 2019
352019
Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells
A Dattani, D Kao, Y Mihaylova, P Abnave, S Hughes, A Lai, S Sahu, ...
Genome research 28 (10), 1543-1554, 2018
352018
Identifying adults at high-risk for change in weight and BMI in England: a longitudinal, large-scale, population-based cohort study using electronic health records
M Katsoulis, AG Lai, K Diaz-Ordaz, M Gomes, L Pasea, A Banerjee, ...
The Lancet Diabetes & Endocrinology 9 (10), 681-694, 2021
322021
Conservation of epigenetic regulation by the MLL3/4 tumour suppressor in planarian pluripotent stem cells
Y Mihaylova, P Abnave, D Kao, S Hughes, A Lai, F Jaber-Hijazi, ...
Nature communications 9 (1), 3633, 2018
322018
The hypoxic tumour microenvironment: A safe haven for immunosuppressive cells and a therapeutic barrier to overcome
WH Chang, AG Lai
Cancer Letters 487, 34-44, 2020
302020
Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies
WH Chang, AG Lai
Journal of translational medicine 17, 1-16, 2019
292019
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Articles 1–20