CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses AG Lai, CJ Doherty, B Mueller-Roeber, SA Kay, JHM Schippers, ... Proceedings of the National Academy of Sciences 109 (42), 17129-17134, 2012 | 341 | 2012 |
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer … AG Lai, L Pasea, A Banerjee, G Hall, S Denaxas, WH Chang, M Katsoulis, ... BMJ open 10 (11), e043828, 2020 | 235 | 2020 |
Estimating excess mortality in people with cancer and multimorbidity in the COVID-19 emergency AG Lai, L Pasea, A Banerjee, S Denaxas, M Katsoulis, WH Chang, ... MedRxiv, 2020.05. 27.20083287, 2020 | 177 | 2020 |
The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion D Kao, AG Lai, E Stamataki, S Rosic, N Konstantinides, E Jarvis, ... elife 5, e20062, 2016 | 148 | 2016 |
Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic A Banerjee, S Chen, L Pasea, AG Lai, M Katsoulis, S Denaxas, V Nafilyan, ... European journal of preventive cardiology 28 (14), 1599-1609, 2021 | 100 | 2021 |
Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource A Wood, R Denholm, S Hollings, J Cooper, S Ip, V Walker, S Denaxas, ... bmj 373, 2021 | 81 | 2021 |
EvoRegen in animals: time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes AG Lai, AA Aboobaker Developmental biology 433 (2), 118-131, 2018 | 68 | 2018 |
The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication X Zhuang, A Magri, M Hill, AG Lai, A Kumar, SB Rambhatla, CL Donald, ... Nature communications 10 (1), 377, 2019 | 61 | 2019 |
Interplay between circadian clock and viral infection X Zhuang, SB Rambhatla, AG Lai, JA McKeating Journal of Molecular Medicine 95, 1283-1289, 2017 | 58 | 2017 |
Comparative genomic analysis of innate immunity reveals novel and conserved components in crustacean food crop species AG Lai, AA Aboobaker BMC genomics 18 (1), 1-26, 2017 | 50 | 2017 |
Obesity during the COVID-19 pandemic: both cause of high risk and potential effect of lockdown? A population-based electronic health record study M Katsoulis, L Pasea, AG Lai, RJB Dobson, S Denaxas, H Hemingway, ... Public Health 191, 41-47, 2021 | 44 | 2021 |
The pan‐cancer mutational landscape of the PPAR pathway reveals universal patterns of dysregulated metabolism and interactions with tumor immunity and hypoxia WH Chang, AG Lai Annals of the New York Academy of Sciences 1448 (1), 65-82, 2019 | 42 | 2019 |
Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance WH Chang, D Forde, AG Lai Cancer Communications 39 (1), 1-14, 2019 | 39 | 2019 |
A novel signature derived from immunoregulatory and hypoxia genes predicts prognosis in liver and five other cancers WH Chang, D Forde, AG Lai Journal of translational medicine 17 (1), 1-12, 2019 | 38 | 2019 |
Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with hypoxia and immunoevasion WH Chang, AG Lai British journal of cancer 121 (8), 666-678, 2019 | 35 | 2019 |
Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells A Dattani, D Kao, Y Mihaylova, P Abnave, S Hughes, A Lai, S Sahu, ... Genome research 28 (10), 1543-1554, 2018 | 35 | 2018 |
Identifying adults at high-risk for change in weight and BMI in England: a longitudinal, large-scale, population-based cohort study using electronic health records M Katsoulis, AG Lai, K Diaz-Ordaz, M Gomes, L Pasea, A Banerjee, ... The Lancet Diabetes & Endocrinology 9 (10), 681-694, 2021 | 32 | 2021 |
Conservation of epigenetic regulation by the MLL3/4 tumour suppressor in planarian pluripotent stem cells Y Mihaylova, P Abnave, D Kao, S Hughes, A Lai, F Jaber-Hijazi, ... Nature communications 9 (1), 3633, 2018 | 32 | 2018 |
The hypoxic tumour microenvironment: A safe haven for immunosuppressive cells and a therapeutic barrier to overcome WH Chang, AG Lai Cancer Letters 487, 34-44, 2020 | 30 | 2020 |
Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies WH Chang, AG Lai Journal of translational medicine 17, 1-16, 2019 | 29 | 2019 |