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Danielle Townsley
Danielle Townsley
MedImmune, Clinical Development
Adresă de e-mail confirmată pe medimmune.com
Titlu
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Somatic mutations and clonal hematopoiesis in aplastic anemia
T Yoshizato, B Dumitriu, K Hosokawa, H Makishima, K Yoshida, ...
New England Journal of Medicine 373 (1), 35-47, 2015
6382015
Eltrombopag added to standard immunosuppression for aplastic anemia
DM Townsley, P Scheinberg, T Winkler, R Desmond, B Dumitriu, O Rios, ...
New England Journal of Medicine 376 (16), 1540-1550, 2017
5002017
Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug
R Desmond, DM Townsley, B Dumitriu, MJ Olnes, P Scheinberg, ...
Blood, The Journal of the American Society of Hematology 123 (12), 1818-1825, 2014
4322014
Danazol treatment for telomere diseases
DM Townsley, B Dumitriu, D Liu, A Biancotto, B Weinstein, C Chen, ...
New England Journal of Medicine 374 (20), 1922-1931, 2016
4022016
Bone marrow failure and the telomeropathies
DM Townsley, B Dumitriu, NS Young
Blood, The Journal of the American Society of Hematology 124 (18), 2775-2783, 2014
3072014
GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia
KA Ganapathi, DM Townsley, AP Hsu, DC Arthur, CS Zerbe, ...
Blood, The Journal of the American Society of Hematology 125 (1), 56-70, 2015
1682015
Hematologic complications of pregnancy
DM Townsley
Seminars in hematology 50 (3), 222-231, 2013
1592013
Memory stem T cells in autoimmune disease: high frequency of circulating CD8+ memory stem cells in acquired aplastic anemia
K Hosokawa, P Muranski, X Feng, DM Townsley, B Liu, J Knickelbein, ...
The Journal of Immunology 196 (4), 1568-1578, 2016
1032016
Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag
T Winkler, X Fan, J Cooper, R Desmond, DJ Young, DM Townsley, ...
Blood, The Journal of the American Society of Hematology 133 (24), 2575-2585, 2019
992019
Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ
LJ Alvarado, HD Huntsman, H Cheng, DM Townsley, T Winkler, X Feng, ...
Blood, The Journal of the American Society of Hematology 133 (19), 2043-2055, 2019
962019
Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia
B Dumitriu, X Feng, DM Townsley, Y Ueda, T Yoshizato, RT Calado, ...
Blood, The Journal of the American Society of Hematology 125 (4), 706-709, 2015
772015
Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells
H Schlums, M Jung, H Han, J Theorell, V Bigley, SCC Chiang, DSJ Allan, ...
Blood, The Journal of the American Society of Hematology 129 (14), 1927-1939, 2017
742017
Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes
L Guidugli, AK Johnson, G Alkorta-Aranburu, V Nelakuditi, K Arndt, ...
Leukemia 31 (5), 1226-1229, 2017
702017
Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes
DM Townsley, R Desmond, CE Dunbar, NS Young
International journal of hematology 98, 48-55, 2013
632013
Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells
X Zhao, S Gao, Z Wu, S Kajigaya, X Feng, Q Liu, DM Townsley, J Cooper, ...
Blood, The Journal of the American Society of Hematology 130 (25), 2762-2773, 2017
622017
Safety and clinical activity of MEDI0562, a humanized OX40 agonist monoclonal antibody, in adult patients with advanced solid tumors
BS Glisson, RS Leidner, RL Ferris, J Powderly, NA Rizvi, B Keam, ...
Clinical Cancer Research 26 (20), 5358-5367, 2020
592020
Understanding the evolving phenotype of vascular complications in telomere biology disorders
C Higgs, YJ Crow, DM Adams, E Chang, D Hayes, U Herbig, JN Huang, ...
Angiogenesis 22, 95-102, 2019
592019
Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome
A Vicente, BA Patel, F Gutierrez-Rodrigues, EM Groarke, V Giudice, ...
Haematologica 105 (12), 2785, 2020
512020
Pathogenic TERT promoter variants in telomere diseases
F Gutierrez-Rodrigues, FS Donaires, A Pinto, A Vicente, LW Dillon, ...
Genetics in Medicine 21 (7), 1594-1602, 2019
502019
Pulmonary arteriovenous malformations: an uncharacterised phenotype of dyskeratosis congenita and related telomere biology disorders
PP Khincha, AA Bertuch, S Agarwal, DM Townsley, NS Young, S Keel, ...
European Respiratory Journal 49 (1), 2017
492017
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