|Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture|
AM Paşca, SA Sloan, LE Clarke, Y Tian, CD Makinson, N Huber, CH Kim, ...
Nature methods 12 (7), 671-678, 2015
|Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome|
SP Paşca, T Portmann, I Voineagu, M Yazawa, A Shcheglovitov, ...
Nature medicine 17 (12), 1657, 2011
|Assembly of functionally integrated human forebrain spheroids|
F Birey, J Andersen, CD Makinson, S Islam, W Wei, N Huber, HC Fan, ...
Nature 545 (7652), 54-59, 2017
|Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain|
BE Deverman, PL Pravdo, BP Simpson, SR Kumar, KY Chan, A Banerjee, ...
Nature biotechnology 34 (2), 204-209, 2016
|Human astrocyte maturation captured in 3D cerebral cortical spheroids derived from pluripotent stem cells|
SA Sloan, S Darmanis, N Huber, TA Khan, F Birey, C Caneda, R Reimer, ...
Neuron 95 (4), 779-790. e6, 2017
|Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons|
JF Krey, SP Paşca, A Shcheglovitov, M Yazawa, R Schwemberger, ...
Nature neuroscience 16 (2), 201-209, 2013
|The rise of three-dimensional human brain cultures|
Nature 553 (7689), 437-445, 2018
|High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism|
SP Paşca, B Nemeş, L Vlase, CE Gagyi, E Dronca, AC Miu, M Dronca
Life sciences 78 (19), 2244-2248, 2006
|One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders|
SP Paşca, E Dronca, T Kaucsár, EC Crǎciun, E Endreffy, BK Ferencz, ...
Journal of cellular and molecular medicine 13 (10), 4229-4238, 2009
|Building models of brain disorders with three-dimensional organoids|
ND Amin, SP Paşca
Neuron 100 (2), 389-405, 2018
|Reliability of human cortical organoid generation|
SJ Yoon, LS Elahi, AM Pașca, RM Marton, A Gordon, O Revah, Y Miura, ...
Nature methods 16 (1), 75-78, 2019
|Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures|
RM Marton, Y Miura, SA Sloan, Q Li, O Revah, RJ Levy, JR Huguenard, ...
Nature neuroscience 22 (3), 484-491, 2019
|Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring|
Y Cao, M Hjort, H Chen, F Birey, SA Leal-Ortiz, CM Han, JG Santiago, ...
Proceedings of the National Academy of Sciences 114 (10), E1866-E1874, 2017
|The ethics of experimenting with human brain tissue|
NA Farahany, HT Greely, S Hyman, C Koch, C Grady, SP Pașca, ...
Nature 556 (7702), 429, 2018
|A deleterious Nav1. 1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients|
Y Sun, SP Paşca, T Portmann, C Goold, KA Worringer, W Guan, KC Chan, ...
Elife 5, e13073, 2016
|Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome|
Y Tian, I Voineagu, SP Paşca, H Won, V Chandran, S Horvath, ...
Genome medicine 6 (10), 75, 2014
|Generating human neurons in vitro and using them to understand neuropsychiatric disease|
SP Paşca, G Panagiotakos, RE Dolmetsch
Annual review of neuroscience 37, 479-501, 2014
|Generation and assembly of human brain region–specific three-dimensional cultures|
SA Sloan, J Andersen, AM Pașca, F Birey, SP Pașca
Nature protocols 13 (9), 2062-2085, 2018
|Engineered materials for organoid systems|
MJ Kratochvil, AJ Seymour, TL Li, SP Paşca, CJ Kuo, SC Heilshorn
Nature Reviews Materials 4 (9), 606-622, 2019
|MicroRNA-9 couples brain neurogenesis and angiogenesis|
R Madelaine, SA Sloan, N Huber, JH Notwell, LC Leung, G Skariah, ...
Cell reports 20 (7), 1533-1542, 2017