Genome-informed targeted therapy for osteosarcoma LC Sayles, MR Breese, AL Koehne, SG Leung, AG Lee, HY Liu, ... Cancer discovery 9 (1), 46-63, 2019 | 292 | 2019 |
NGSUtils: a software suite for analyzing and manipulating next-generation sequencing datasets MR Breese, Y Liu Bioinformatics 29 (4), 494-496, 2013 | 267 | 2013 |
Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis MM Howarth, D Simpson, SP Ngok, B Nieves, R Chen, Z Siprashvili, ... The Journal of clinical investigation 124 (12), 5275-5290, 2014 | 96 | 2014 |
Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress S Oh, RA Flynn, SN Floor, J Purzner, L Martin, BT Do, S Schubert, D Vaka, ... Oncotarget 7 (19), 28169, 2016 | 80 | 2016 |
Genome-informed targeted therapy for osteosarcoma. Cancer Discov. 2019; 9: 46–63. doi: 10.1158/2159-8290 LC Sayles, MR Breese, AL Koehne, SG Leung, AG Lee, HY Liu, ... CD-17-1152.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 38 | |
Alt Event Finder: a tool for extracting alternative splicing events from RNA-seq data A Zhou, MR Breese, Y Hao, HJ Edenberg, L Li, TC Skaar, Y Liu BMC genomics 13, 1-10, 2012 | 29 | 2012 |
A comprehensive circulating tumor DNA assay for detection of translocation and copy-number changes in pediatric sarcomas AT Shah, TD Azad, MR Breese, JJ Chabon, EG Hamilton, K Straessler, ... Molecular cancer therapeutics 20 (10), 2016-2025, 2021 | 18 | 2021 |
Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids H Song, S Bucher, K Rosenberg, M Tsui, D Burhan, D Hoffman, SJ Cho, ... Nature communications 13 (1), 4878, 2022 | 16 | 2022 |
Complete response to PD-1 inhibition in an adolescent with relapsed clear cell adenocarcinoma of the cervix predicted by neoepitope burden and APOBEC signature A Levinson, AG Lee, HJ Martell, MR Breese, C Zaloudek, J Van Ziffle, ... JCO Precision Oncology 4, 2020 | 6 | 2020 |
Labrat LIMS: an extensible framework for developing laboratory information management, analysis, and bioinformatics solutions for microarrays MR Breese, MJ Stephens, JN McClintick, MW Grows, HJ Edenberg Proceedings of the 2003 ACM symposium on Applied computing, 103-108, 2003 | 6 | 2003 |
NUP98-NSD1 driven MDS/MPN in childhood masquerading as JMML A Behnert, AG Lee, EP Young, MR Breese, SG Leung, I Behroozfard, ... Journal of pediatric hematology/oncology 43 (6), e808-e811, 2021 | 5 | 2021 |
Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures J Pfeil, LM Sanders, I Anastopoulos, AG Lyle, AS Weinstein, Y Xue, ... PLoS computational biology 16 (4), e1007753, 2020 | 4 | 2020 |
Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor LM Sanders, A Rangaswami, I Bjork, HC Beale, ET Kephart, A Durbin, ... Molecular Case Studies 5 (5), a004317, 2019 | 4 | 2019 |
Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities CR Schott, AL Koehne, LC Sayles, EP Young, C Luck, K Yu, AG Lee, ... bioRxiv, 2023.01. 19.524562, 2023 | 3 | 2023 |
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods N Null, S Jain, C Bakolitsa, SE Brenner, P Radivojac, J Moult, S Repo, ... Genome Biology 25 (1), 1-46, 2024 | 2 | 2024 |
Abstract A35: Characterization of the genomic landscape of osteosarcoma metastasis AL Koehne, LC Sayles, MR Breese, D Vaka, A Sweet-Cordero Cancer Research 76 (5_Supplement), A35-A35, 2016 | 2 | 2016 |
Using genome engineering to prospectively investigate the pathogenesis of MLL translocations in infant acute lymphoblastic leukemia EH Breese, C Dawson, C Buechele, MR Breese, ML Cleary, MH Porteus Blood 122 (21), 3722, 2013 | 2 | 2013 |
FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer S Menon, MR Breese, YP Lin, H Allegakoen, S Perati, A Heslin, ... bioRxiv, 2023 | 1 | 2023 |
Targeted drug therapies for osteosarcoma LC Sayles, A Koehne, K Marini, AG Lee, SG Leung, AT Shah, MR Breese, ... Cancer Research 79 (13_Supplement), 2880-2880, 2019 | 1 | 2019 |
Tumor-specific copy number alterations uncover therapeutic opportunities in osteosarcoma LC Sayles, M Breese, AL Koehne, S Leung, A Spillinger, A Lee, A Shah, ... Cancer Research 77 (13_Supplement), 1948-1948, 2017 | 1 | 2017 |