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Marcus R. Breese
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Genome-informed targeted therapy for osteosarcoma
LC Sayles, MR Breese, AL Koehne, SG Leung, AG Lee, HY Liu, ...
Cancer discovery 9 (1), 46-63, 2019
2922019
NGSUtils: a software suite for analyzing and manipulating next-generation sequencing datasets
MR Breese, Y Liu
Bioinformatics 29 (4), 494-496, 2013
2672013
Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis
MM Howarth, D Simpson, SP Ngok, B Nieves, R Chen, Z Siprashvili, ...
The Journal of clinical investigation 124 (12), 5275-5290, 2014
962014
Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress
S Oh, RA Flynn, SN Floor, J Purzner, L Martin, BT Do, S Schubert, D Vaka, ...
Oncotarget 7 (19), 28169, 2016
802016
Genome-informed targeted therapy for osteosarcoma. Cancer Discov. 2019; 9: 46–63. doi: 10.1158/2159-8290
LC Sayles, MR Breese, AL Koehne, SG Leung, AG Lee, HY Liu, ...
CD-17-1152.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
38
Alt Event Finder: a tool for extracting alternative splicing events from RNA-seq data
A Zhou, MR Breese, Y Hao, HJ Edenberg, L Li, TC Skaar, Y Liu
BMC genomics 13, 1-10, 2012
292012
A comprehensive circulating tumor DNA assay for detection of translocation and copy-number changes in pediatric sarcomas
AT Shah, TD Azad, MR Breese, JJ Chabon, EG Hamilton, K Straessler, ...
Molecular cancer therapeutics 20 (10), 2016-2025, 2021
182021
Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids
H Song, S Bucher, K Rosenberg, M Tsui, D Burhan, D Hoffman, SJ Cho, ...
Nature communications 13 (1), 4878, 2022
162022
Complete response to PD-1 inhibition in an adolescent with relapsed clear cell adenocarcinoma of the cervix predicted by neoepitope burden and APOBEC signature
A Levinson, AG Lee, HJ Martell, MR Breese, C Zaloudek, J Van Ziffle, ...
JCO Precision Oncology 4, 2020
62020
Labrat LIMS: an extensible framework for developing laboratory information management, analysis, and bioinformatics solutions for microarrays
MR Breese, MJ Stephens, JN McClintick, MW Grows, HJ Edenberg
Proceedings of the 2003 ACM symposium on Applied computing, 103-108, 2003
62003
NUP98-NSD1 driven MDS/MPN in childhood masquerading as JMML
A Behnert, AG Lee, EP Young, MR Breese, SG Leung, I Behroozfard, ...
Journal of pediatric hematology/oncology 43 (6), e808-e811, 2021
52021
Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures
J Pfeil, LM Sanders, I Anastopoulos, AG Lyle, AS Weinstein, Y Xue, ...
PLoS computational biology 16 (4), e1007753, 2020
42020
Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor
LM Sanders, A Rangaswami, I Bjork, HC Beale, ET Kephart, A Durbin, ...
Molecular Case Studies 5 (5), a004317, 2019
42019
Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities
CR Schott, AL Koehne, LC Sayles, EP Young, C Luck, K Yu, AG Lee, ...
bioRxiv, 2023.01. 19.524562, 2023
32023
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
N Null, S Jain, C Bakolitsa, SE Brenner, P Radivojac, J Moult, S Repo, ...
Genome Biology 25 (1), 1-46, 2024
22024
Abstract A35: Characterization of the genomic landscape of osteosarcoma metastasis
AL Koehne, LC Sayles, MR Breese, D Vaka, A Sweet-Cordero
Cancer Research 76 (5_Supplement), A35-A35, 2016
22016
Using genome engineering to prospectively investigate the pathogenesis of MLL translocations in infant acute lymphoblastic leukemia
EH Breese, C Dawson, C Buechele, MR Breese, ML Cleary, MH Porteus
Blood 122 (21), 3722, 2013
22013
FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer
S Menon, MR Breese, YP Lin, H Allegakoen, S Perati, A Heslin, ...
bioRxiv, 2023
12023
Targeted drug therapies for osteosarcoma
LC Sayles, A Koehne, K Marini, AG Lee, SG Leung, AT Shah, MR Breese, ...
Cancer Research 79 (13_Supplement), 2880-2880, 2019
12019
Tumor-specific copy number alterations uncover therapeutic opportunities in osteosarcoma
LC Sayles, M Breese, AL Koehne, S Leung, A Spillinger, A Lee, A Shah, ...
Cancer Research 77 (13_Supplement), 1948-1948, 2017
12017
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Articole 1–20