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Maria Reinecke
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The target landscape of clinical kinase drugs
S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ...
Science 358 (6367), eaan4368, 2017
7372017
Multi-level proteomics reveals host-perturbation strategies of SARS-CoV-2 and SARS-CoV
A Stukalov, V Girault, V Grass, V Bergant, O Karayel, C Urban, DA Haas, ...
Biorxiv, 2020
586*2020
Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
Y Bian, R Zheng, FP Bayer, C Wong, YC Chang, C Meng, DP Zolg, ...
Nature Communications 11 (1), 1-12, 2020
2782020
ProteomicsDB: a multi-omics and multi-organism resource for life science research
P Samaras, T Schmidt, M Frejno, S Gessulat, M Reinecke, A Jarzab, ...
Nucleic acids research 48 (D1), D1153-D1163, 2020
1852020
Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms
P Le, E Kunold, R Macsics, K Rox, MC Jennings, I Ugur, M Reinecke, ...
Nature Chemistry 12 (2), 145-158, 2020
842020
Decrypting drug actions and protein modifications by dose-and time-resolved proteomics
J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ...
Science 380 (6640), 93-101, 2023
242023
Chemoproteomic selectivity profiling of PIKK and PI3K kinase inhibitors
M Reinecke, B Ruprecht, S Poser, S Wiechmann, M Wilhelm, ...
ACS chemical biology 14 (4), 655-664, 2019
242019
Adaptive resistance to EGFR-targeted therapy by calcium signaling in NSCLC cells
C Mulder, N Prust, S Van Doorn, M Reinecke, B Kuster, ...
Molecular Cancer Research 16 (11), 1773-1784, 2018
192018
Kinobeads: A Chemical Proteomic Approach for Kinase Inhibitor Selectivity Profiling and Target Discovery
M Reinecke, S Heinzlmeir, M Wilhelm, G Médard, S Klaeger, B Kuster
Target Discovery and Validation: Methods and Strategies for Drug Discovery …, 2019
112019
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors
M Reinecke, P Brear, L Vornholz, BT Berger, F Seefried, S Wilhelm, ...
Nature Chemical Biology, 1-9, 2023
92023
Optimization of the Lead Compound NVP‐BHG712 as a Colorectal Cancer Inhibitor
A Tröster, M DiPrima, N Jores, D Kudlinzki, S Sreeramulu, SL Gande, ...
Chemistry–A European Journal 29 (23), e202203967, 2023
42023
CiRCus: a framework to enable classification of complex high-throughput experiments
F Seefried, T Schmidt, M Reinecke, S Heinzlmeir, B Kuster, M Wilhelm
Journal of proteome research 18 (4), 1486-1493, 2019
42019
Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity
V Němec, P Khirsariya, P Janovská, PM Moyano, L Maier, P Procházková, ...
Angewandte Chemie 135 (11), e202217532, 2023
22023
Identifying small molecule probes for kinases by chemical proteomics
M Reinecke
Technische Universität München, 2020
22020
Multi-level proteomics reveals host-perturbation strategies of SARS-CoV-2 and SARS-CoV. bioRxiv 2020.06. 17.156455 [Preprint]. 17 June 2020
A Stukalov, V Girault, V Grass, V Bergant, O Karayel, C Urban, DA Haas, ...
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