Urmăriți
Nick Haining
Nick Haining
Assistant Professor, Harvard Medical School
Adresă de e-mail confirmată pe dfci.harvard.edu - Pagina de pornire
Titlu
Citat de
Citat de
Anul
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
EJ Wherry, SJ Ha, SM Kaech, WN Haining, S Sarkar, V Kalia, ...
Immunity 27 (4), 670-684, 2007
24612007
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
SD Blackburn, H Shin, WN Haining, T Zou, CJ Workman, A Polley, ...
Nature immunology 10 (1), 29-37, 2009
24462009
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
BC Miller, DR Sen, R Al Abosy, K Bi, YV Virkud, MW LaFleur, KB Yates, ...
Nature immunology 20 (3), 326-336, 2019
16422019
Defining ‘T cell exhaustion’
CU Blank, WN Haining, W Held, PG Hogan, A Kallies, E Lugli, RC Lynn, ...
Nature Reviews Immunology 19 (11), 665-674, 2019
12672019
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
KE Pauken, MA Sammons, PM Odorizzi, S Manne, J Godec, O Khan, ...
Science 354 (6316), 1160-1165, 2016
12272016
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
RT Manguso, HW Pope, MD Zimmer, FD Brown, KB Yates, BC Miller, ...
Nature 547 (7664), 413-418, 2017
10852017
Densely interconnected transcriptional circuits control cell states in human hematopoiesis
N Novershtern, A Subramanian, LN Lawton, RH Mak, WN Haining, ...
Cell 144 (2), 296-309, 2011
10822011
Normalizing the environment recapitulates adult human immune traits in laboratory mice
LK Beura, SE Hamilton, K Bi, JM Schenkel, OA Odumade, KA Casey, ...
Nature 532 (7600), 512-516, 2016
10692016
The epigenetic landscape of T cell exhaustion
DR Sen, J Kaminski, RA Barnitz, M Kurachi, U Gerdemann, KB Yates, ...
Science 354 (6316), 1165-1169, 2016
9122016
Systems biology of vaccination for seasonal influenza in humans
HI Nakaya, J Wrammert, EK Lee, L Racioppi, S Marie-Kunze, WN Haining, ...
Nature immunology 12 (8), 786-795, 2011
8932011
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity
VR Juneja, KA McGuire, RT Manguso, MW LaFleur, N Collins, ...
Journal of Experimental Medicine 214 (4), 895-904, 2017
8372017
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
S Sarkar, V Kalia, WN Haining, BT Konieczny, S Subramaniam, R Ahmed
The Journal of experimental medicine 205 (3), 625-640, 2008
8142008
Prolonged interleukin-2Rα expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo
V Kalia, S Sarkar, S Subramaniam, WN Haining, KA Smith, R Ahmed
Immunity 32 (1), 91-103, 2010
7422010
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
6422018
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ...
Nature medicine 16 (10), 1147-1151, 2010
6142010
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ...
Nature 565 (7737), 43-48, 2019
5562019
Origin and differentiation of human memory CD8 T cells after vaccination
RS Akondy, M Fitch, S Edupuganti, S Yang, HT Kissick, KW Li, ...
Nature 552 (7685), 362-367, 2017
5382017
Stable inhibitory activity of regulatory T cells requires the transcription factor Helios
HJ Kim, RA Barnitz, T Kreslavsky, FD Brown, H Moffett, ME Lemieux, ...
Science 350 (6258), 334-339, 2015
4292015
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
PK Gupta, J Godec, D Wolski, E Adland, K Yates, KE Pauken, C Cosgrove, ...
PLoS pathogens 11 (10), e1005177, 2015
4222015
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
M Kurachi, RA Barnitz, N Yosef, PM Odorizzi, MA DiIorio, ME Lemieux, ...
Nature immunology 15 (4), 373-383, 2014
3682014
Sistemul nu poate realiza operația în acest moment. Încercați din nou mai târziu.
Articole 1–20