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Jianjun Chen
Jianjun Chen
Beckman Research Institute of City of Hope, University of Cincinnati, University of Chicago
Verified email at coh.org - Homepage
Title
Cited by
Cited by
Year
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ...
Nature cell biology 20 (3), 285-295, 2018
18722018
FTO plays an oncogenic role in acute myeloid leukemia as a N6-methyladenosine RNA demethylase
Z Li, H Weng, R Su, X Weng, Z Zuo, C Li, H Huang, S Nachtergaele, ...
Cancer cell 31 (1), 127-141, 2017
12452017
R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling
R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ...
Cell 172 (1), 90-105. e23, 2018
8422018
METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification
H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ...
Cell stem cell 22 (2), 191-205. e9, 2018
8102018
m6A modification in coding and non-coding RNAs: roles and therapeutic implications in cancer
H Huang, H Weng, J Chen
Cancer cell 37 (3), 270-288, 2020
7592020
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia
S Mi, J Lu, M Sun, Z Li, H Zhang, MB Neilly, Y Wang, Z Qian, J Jin, ...
Proceedings of the National Academy of Sciences 104 (50), 19971-19976, 2007
6632007
miR-21 plays a pivotal role in gastric cancer pathogenesis and progression
Z Zhang, Z Li, C Gao, P Chen, J Chen, W Liu, S Xiao, H Lu
Laboratory investigation 88 (12), 1358-1366, 2008
6562008
RNA N6-methyladenosine modification in cancers: current status and perspectives
X Deng, R Su, H Weng, H Huang, Z Li, J Chen
Cell research 28 (5), 507-517, 2018
5922018
Differential m6A, m6Am, and m1A demethylation mediated by FTO in the cell nucleus and cytoplasm
J Wei, F Liu, Z Lu, Q Fei, Y Ai, PC He, H Shi, X Cui, R Su, A Klungland, ...
Molecular cell 71 (6), 973-985. e5, 2018
5852018
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations
Z Li, J Lu, M Sun, S Mi, H Zhang, RT Luo, P Chen, Y Wang, M Yan, Z Qian, ...
Proceedings of the National Academy of Sciences 105 (40), 15535-15540, 2008
5752008
Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia
Y Huang, R Su, Y Sheng, L Dong, Z Dong, H Xu, T Ni, ZS Zhang, T Zhang, ...
Cancer cell 35 (4), 677-691. e10, 2019
5732019
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ...
Nature 567 (7748), 414-419, 2019
4852019
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ...
Cancer cell 38 (1), 79-96. e11, 2020
4322020
Leukaemogenesis: more than mutant genes
J Chen, O Odenike, JD Rowley
Nature Reviews Cancer 10 (1), 23-36, 2010
3902010
MicroRNA and cancer: Current status and prospective
W Wu, M Sun, GM Zou, J Chen
International Journal of Cancer 120 (5), 953-960, 2007
3872007
Over 20% of human transcripts might form sense–antisense pairs
J Chen, M Sun, WJ Kent, X Huang, H Xie, W Wang, G Zhou, RZ Shi, ...
Nucleic acids research 32 (16), 4812-4820, 2004
3842004
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner
S Müller, M Glaß, AK Singh, J Haase, N Bley, T Fuchs, M Lederer, A Dahl, ...
Nucleic acids research 47 (1), 375-390, 2019
2922019
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis
M Sun, CX Song, H Huang, CA Frankenberger, D Sankarasharma, ...
Proceedings of the National Academy of Sciences 110 (24), 9920-9925, 2013
2842013
Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization
R Popovic, LE Riesbeck, CS Velu, A Chaubey, J Zhang, NJ Achille, ...
Blood, The Journal of the American Society of Hematology 113 (14), 3314-3322, 2009
2702009
RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia
C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ...
Cell stem cell 27 (1), 64-80. e9, 2020
2662020
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