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Simon Jochems, PhD
Simon Jochems, PhD
Leiden University Medical Center
Verified email at lumc.nl
Title
Cited by
Cited by
Year
COVID-19 in Africa: Dampening the storm?
M Mbow, B Lell, SP Jochems, B Cisse, S Mboup, BG Dewals, A Jaye, ...
Science 369 (6504), 624-626, 2020
2132020
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus
SP Jochems, F Marcon, BF Carniel, M Holloway, E Mitsi, E Smith, ...
Nature immunology 19 (12), 1299-1308, 2018
1722018
A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics
MCC Langenberg, MA Hoogerwerf, JPR Koopman, JJ Janse, ...
Nature medicine 26 (3), 326-332, 2020
1232020
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19
AHE Roukens, CR Pothast, M König, W Huisman, T Dalebout, T Tak, ...
Nature immunology 23 (1), 23-32, 2022
1072022
The immunological mechanisms that control pneumococcal carriage
SP Jochems, JN Weiser, R Malley, DM Ferreira
PLoS pathogens 13 (12), e1006665, 2017
1032017
Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
WAA de Steenhuijsen Piters, SP Jochems, E Mitsi, J Rylance, S Pojar, ...
Nature communications 10 (1), 2981, 2019
792019
Novel analysis of immune cells from nasal microbiopsy demonstrates reliable, reproducible data for immune populations, and superior cytokine detection compared to nasal wash
SP Jochems, K Piddock, J Rylance, H Adler, BF Carniel, A Collins, ...
PloS one 12 (1), e0169805, 2017
762017
Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection
B Jacquelin, G Petitjean, D Kunkel, AS Liovat, SP Jochems, KA Rogers, ...
PLoS pathogens 10 (7), e1004241, 2014
662014
Elevated basal pre-infection CXCL10 in plasma and in the small intestine after infection are associated with more rapid HIV/SIV disease onset
MJ Ploquin, Y Madec, A Casrouge, N Huot, C Passaes, C Lécuroux, ...
PLoS pathogens 12 (8), e1005774, 2016
642016
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, ...
Nature communications 10 (1), 3060, 2019
612019
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization
SP Jochems, K de Ruiter, C Solórzano, A Voskamp, E Mitsi, E Nikolaou, ...
The Journal of clinical investigation 129 (10), 2022
572022
Helminth infections drive heterogeneity in human type 2 and regulatory cells
K de Ruiter, SP Jochems, DL Tahapary, KA Stam, M König, V van Unen, ...
Science translational medicine 12 (524), eaaw3703, 2020
572020
Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine
BF Carniel, F Marcon, J Rylance, EL German, S Zaidi, J Reiné, E Negera, ...
JCI insight 6 (4), 2021
442021
Nasal pneumococcal density is associated with microaspiration and heightened human alveolar macrophage responsiveness to bacterial pathogens
E Mitsi, B Carniel, J Reiné, J Rylance, S Zaidi, A Soares-Schanoski, ...
American Journal of Respiratory and Critical Care Medicine 201 (3), 335-347, 2020
442020
Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity
SE de Jong, V van Unen, MD Manurung, KA Stam, JJ Goeman, ...
Nature Immunology 22 (5), 654-665, 2021
392021
Biomarkers of the ageing immune system and their association with frailty–A systematic review
ET Van Hoi, NA De Glas, JEA Portielje, D Van Heemst, F Van Den Bos, ...
Experimental Gerontology 176, 112163, 2023
342023
Two randomized trials of the effect of live attenuated influenza vaccine on pneumococcal colonization
J Rylance, WAA de Steenhuijsen Piters, MJ Mina, D Bogaert, N French, ...
American journal of respiratory and critical care medicine 199 (9), 1160-1163, 2019
342019
Intact type I Interferon production and IRF7 function in sooty mangabeys
SE Bosinger, ZP Johnson, KA Folkner, N Patel, T Hashempour, ...
PLoS pathogens 9 (8), e1003597, 2013
342013
Experimental human pneumococcal colonization in older adults is feasible and safe, not immunogenic
H Adler, EL German, E Mitsi, E Nikolaou, S Pojar, C Hales, R Robinson, ...
American journal of respiratory and critical care medicine 203 (5), 604-613, 2021
292021
Innate immunity in the control of HIV/AIDS: recent advances and open questions
MJY Ploquin, B Jacquelin, SP Jochems, F Barré-Sinoussi, ...
Aids 26 (10), 1269-1279, 2012
282012
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