Annalida Bedini
Annalida Bedini
researcher dipartimento di scienze biomolecolari
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Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand
R Ochoa-Sanchez, S Comai, B Lacoste, FR Bambico, ...
Journal of Neuroscience 31 (50), 18439-18452, 2011
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism
P Sestili, G Diamantini, A Bedini, L Cerioni, I Tommasini, G Tarzia, ...
Biochemical Journal 364 (1), 121-128, 2002
2-[N-Acylamino(C1−C3)alkyl]indoles as MT1 Melatonin Receptor Partial Agonists, Antagonists, and Putative Inverse Agonists
G Spadoni, C Balsamini, A Bedini, G Diamantini, B Di Giacomo, A Tontini, ...
Journal of medicinal chemistry 41 (19), 3624-3634, 1998
N-(Substituted-anilinoethyl)amides: Design, Synthesis, and Pharmacological Characterization of a New Class of Melatonin Receptor Ligands
S Rivara, A Lodola, M Mor, A Bedini, G Spadoni, V Lucini, M Pannacci, ...
Journal of medicinal chemistry 50 (26), 6618-6626, 2007
Analysis of Structure−Activity Relationships for MT2 Selective Antagonists by Melatonin MT1 and MT2 Receptor Models
S Rivara, S Lorenzi, M Mor, PV Plazzi, G Spadoni, A Bedini, G Tarzia
Journal of medicinal chemistry 48 (12), 4049-4060, 2005
Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways
M Lopez-Canul, E Palazzo, S Dominguez-Lopez, L Luongo, B Lacoste, ...
Pain 156 (2), 305-317, 2015
Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam
R Ochoa-Sanchez, Q Rainer, S Comai, G Spadoni, A Bedini, S Rivara, ...
Progress in neuro-psychopharmacology and biological psychiatry 39 (2), 318-325, 2012
Melatonin receptor agonists: new options for insomnia and depression treatment
G Spadoni, A Bedini, S Rivara, M Mor
CNS neuroscience & therapeutics 17 (6), 733-741, 2011
Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes
F Radogna, L Paternoster, M De Nicola, C Cerella, S Ammendola, ...
Toxicology and applied pharmacology 239 (1), 37-45, 2009
Melatonin receptor agonists: SAR and applications to the treatment of sleep-wake disorders
S Rivara, M Mor, A Bedini, G Spadoni, G Tarzia
Current topics in medicinal chemistry 8 (11), 954-968, 2008
Synthesis of tryptamine derivatives via a direct, one-pot reductive alkylation of indoles
M Righi, F Topi, S Bartolucci, A Bedini, G Piersanti, G Spadoni
The Journal of Organic Chemistry 77 (14), 6351-6357, 2012
Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands
M Mor, G Spadoni, B Di Giacomo, G Diamantini, A Bedini, G Tarzia, ...
Bioorganic & medicinal chemistry 9 (4), 1045-1057, 2001
Recent advances in the development of melatonin MT1 and MT2 receptor agonists
M Mor, S Rivara, D Pala, A Bedini, G Spadoni, G Tarzia
Expert opinion on therapeutic patents 20 (8), 1059-1077, 2010
Three-Dimensional Quantitative Structure−Activity Relationship Studies on Selected MT1 and MT2 Melatonin Receptor Ligands:  Requirements for Subtype …
S Rivara, M Mor, C Silva, V Zuliani, F Vacondio, G Spadoni, A Bedini, ...
Journal of medicinal chemistry 46 (8), 1429-1439, 2003
Indole‐based analogs of melatonin: in vitro antioxidant and cytoprotective activities
M Mor, C Silva, F Vacondio, PV Plazzi, S Bertoni, G Spadoni, ...
Journal of pineal research 36 (2), 95-102, 2004
Iridium-catalyzed direct synthesis of tryptamine derivatives from indoles: exploiting N-protected β-amino alcohols as alkylating agents
S Bartolucci, M Mari, A Bedini, G Piersanti, G Spadoni
The Journal of Organic Chemistry 80 (6), 3217-3222, 2015
Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012-2014)
S Rivara, D Pala, A Bedini, G Spadoni
Expert opinion on therapeutic patents, 425-441, 2015
Homology models of melatonin receptors: challenges and recent advances
D Pala, A Lodola, A Bedini, G Spadoni, S Rivara
International Journal of Molecular Sciences 14 (4), 8093-8121, 2013
Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells
G Gatti, V Lucini, S Dugnani, A Calastretti, G Spadoni, A Bedini, S Rivara, ...
Oncotarget 8 (40), 68338, 2017
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines
G Spadoni, A Bedini, S Lucarini, M Mari, DH Caignard, JA Boutin, ...
Journal of Medicinal Chemistry 58 (18), 7512-7525, 2015
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