| Cyanobacterial cytotoxicity versus toxicity to brine shrimp Artemia salina D Hisem, P Hrouzek, P Tomek, J Tomšíčková, E Zapomělová, ... Toxicon 57 (1), 76-83, 2011 | 69 | 2011 |
| Cytotoxicity and secondary metabolites production in terrestrial Nostoc strains, originating from different climatic/geographic regions and habitats: Is their … P Hrouzek, P Tomek, A Lukešová, J Urban, L Voloshko, B Pushparaj, ... Environmental toxicology 26 (4), 345-358, 2011 | 55 | 2011 |
| Discovery and evaluation of inhibitors to the immunosuppressive enzyme indoleamine 2, 3-dioxygenase 1 (IDO1): Probing the active site-inhibitor interactions P Tomek, BD Palmer, JU Flanagan, C Sun, EL Raven, LM Ching European journal of medicinal chemistry 126, 983-996, 2017 | 34 | 2017 |
| Tryptophan: A rheostat of cancer immune escape mediated by immunosuppressive enzymes IDO1 and TDO M Kim, P Tomek Frontiers in immunology 12, 636081, 2021 | 32 | 2021 |
| Formation of an N-formylkynurenine-derived fluorophore and its use for measuring indoleamine 2,3-dioxygenase 1 activity P Tomek, BD Palmer, JU Flanagan, SPS Fung, DJA Bridewell, JF Jamie, ... Analytical and bioanalytical chemistry 405, 2515-2524, 2013 | 29 | 2013 |
| Biosynthesis of Colabomycin E, a New Manumycin‐Family Metabolite, Involves an Unusual Chain‐Length Factor K Petříčková, S Pospíšil, M Kuzma, T Tylová, M Jágr, P Tomek, ... ChemBioChem 15 (9), 1334-1345, 2014 | 28 | 2014 |
| Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2, 3-dioxygenase 1 (IDO1) SPS Fung, H Wang, P Tomek, CJ Squire, JU Flanagan, BD Palmer, ... Bioorganic & medicinal chemistry 21 (24), 7595-7603, 2013 | 28 | 2013 |
| Discovery and characterisation of dual inhibitors of tryptophan 2, 3-dioxygenase (TDO2) and indoleamine 2, 3-dioxygenase 1 (IDO1) using virtual screening S Sari, P Tomek, E Leung, J Reynisson Molecules 24 (23), 4346, 2019 | 22 | 2019 |
| Cytotoxic Lipopeptide Muscotoxin A, Isolated from Soil Cyanobacterium Desmonostoc muscorum, Permeabilizes Phospholipid Membranes by Reducing Their … P Tomek, P Hrouzek, M Kuzma, J Sýkora, R Fišer, J Černý, P Novák, ... Chemical Research in Toxicology 28 (2), 216-224, 2015 | 21 | 2015 |
| Validating TDP1 as an inhibition target for the development of chemosensitizers for camptothecin-based chemotherapy drugs E Leung, J Patel, JA Hollywood, A Zafar, P Tomek, D Barker, LI Pilkington, ... Oncology and Therapy 9 (2), 541-556, 2021 | 13 | 2021 |
| Towards establishing extracellular vesicle-associated RNAs as biomarkers for HER2+ breast cancer CL Hisey, P Tomek, YNS Nursalim, LW Chamley, E Leung F1000Research 9, 2020 | 12 | 2020 |
| Formation of fluorophores from the kynurenine pathway metabolite N-formylkynurenine and cyclic amines involves transamidation and carbon–carbon bond formation at the 2-position … P Tomek, BD Palmer, JD Kendall, JU Flanagan, LM Ching Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (9), 1772-1780, 2015 | 11 | 2015 |
| Parallel discovery of selective and dual inhibitors of tryptophan dioxygenases IDO1 and TDO2 with a newly-modified enzymatic assay RC de Iudicibus, P Tomek, BD Palmer, SM Tijono, JU Flanagan, ... Bioorganic & Medicinal Chemistry 39, 116160, 2021 | 8 | 2021 |
| Conjugation of Palbociclib with MHI-148 has an increased cytotoxic effect for breast cancer cells and an altered mechanism of action PJ Choi, P Tomek, M Tercel, J Reynisson, TIH Park, EA Cooper, ... Molecules 27 (3), 880, 2022 | 6 | 2022 |
| Muscotoxins: novel cytotoxic undecapeptides with unique structural elements and mechanism of action, isolated from soil cyanobacterium Nostoc muscorum. P Tomek Jihočeská univerzita, 2010 | 4 | 2010 |
| Imprinted and ancient gene: a potential mediator of cancer cell survival during tryptophan deprivation P Tomek, SK Gore, CL Potts, CG Print, MA Black, A Hallermayr, M Kilian, ... Cell communication and signaling 16, 1-15, 2018 | 3 | 2018 |
| Evaluation of novel inhibitors of tryptophan dioxygenases for enzyme and species selectivity using engineered tumour cell lines expressing either murine or human IDO1 or TDO2 SM Tijono, BD Palmer, P Tomek, JU Flanagan, K Henare, S Gamage, ... Pharmaceuticals 15 (9), 1090, 2022 | 1 | 2022 |
| A Novel Class of Inhibitors of the Immunosuppressive Enzyme indoleamine 2, 3-dioxygenase 1 (IDO1) for the Treatment of Cancer LM Ching, BD Palmer, P Tomek, JU Flanagan, K Henare Proc of American Association for Cancer Research, 2015 | 1 | 2015 |
| Development of truncated Battacin antimicrobials featuring novel N-terminal fatty acids with an excellent safety profile L Posa, P Tomek, S Lamba, V Sarojini, D Barker Bioorganic & Medicinal Chemistry Letters 96, 129535, 2023 | | 2023 |
| Conjugation of palbociclib with MHI-148 has an increased cytotoxic effect for breast cancer cells and an altered mechanism of action E Leung, P Tomek, M Tercel, J Reynisson, T Park, E Cooper, W Denny, ... bioRxiv, 2021.11. 02.466693, 2021 | | 2021 |
