Jason Anthony Vander Heiden
Jason Anthony Vander Heiden
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Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data
NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ...
Bioinformatics 31 (20), 3356-3358, 2015
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ...
Science translational medicine 6 (248), 248ra107-248ra107, 2014
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires
JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’connor, ...
Bioinformatics 30 (13), 1930-1932, 2014
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data
G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ...
Frontiers in immunology 4, 358, 2013
Salmonella infection drives promiscuous B cell activation followed by extrafollicular affinity maturation
R Di Niro, SJ Lee, JA Vander Heiden, RA Elsner, N Trivedi, JM Bannock, ...
Immunity 43 (1), 120-131, 2015
High-resolution antibody dynamics of vaccine-induced immune responses
U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ...
Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014
Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response
BJ Laidlaw, Y Lu, RA Amezquita, JS Weinstein, JA Vander Heiden, ...
Science immunology 2 (16), eaan4767, 2017
In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice
KC Browder, P Reddy, M Yamamoto, A Haghani, IG Guillen, S Sahu, ...
Nature Aging 2 (3), 243-253, 2022
Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants
R Malik, T Freilinger, BS Winsvold, V Anttila, J Vander Heiden, M Traylor, ...
Neurology 84 (21), 2132-2145, 2015
Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells
F Rubelt, CR Bolen, HM McGuire, JAV Heiden, D Gadala-Maria, M Levin, ...
Nature communications 7 (1), 1-12, 2016
Dysregulation of B cell repertoire formation in myasthenia gravis patients revealed through deep sequencing
JA Vander Heiden, P Stathopoulos, JQ Zhou, L Chen, TJ Gilbert, ...
The Journal of Immunology 198 (4), 1460-1473, 2017
Reproducibility and reuse of adaptive immune receptor repertoire data
F Breden, ET Luning Prak, B Peters, F Rubelt, CA Schramm, CE Busse, ...
Frontiers in immunology 8, 1418, 2017
Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination
KB Hoehn, JA Vander Heiden, JQ Zhou, G Lunter, OG Pybus, ...
Proceedings of the National Academy of Sciences 116 (45), 22664-22672, 2019
Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production
E Cotzomi, P Stathopoulos, CS Lee, AM Ritchie, JN Soltys, FR Delmotte, ...
Brain 142 (6), 1598-1615, 2019
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment
A Balestrini, V Joseph, M Dourado, RM Reese, SD Shields, L Rougé, ...
Journal of Experimental Medicine 218 (4), 2021
Genetic analysis for a shared biological basis between migraine and coronary artery disease
BS Winsvold, CP Nelson, R Malik, P Gormley, V Anttila, J Vander Heiden, ...
Neurology: Genetics 1 (1), e10, 2015
AIRR community standardized representations for annotated immune repertoires
JA Vander Heiden, S Marquez, N Marthandan, SAC Bukhari, CE Busse, ...
Frontiers in immunology 9, 2206, 2018
A model of somatic hypermutation targeting in mice based on high-throughput Ig sequencing data
A Cui, R Di Niro, JA Vander Heiden, AW Briggs, K Adams, T Gilbert, ...
The Journal of Immunology 197 (9), 3566-3574, 2016
Serum metabolomics reveals higher levels of polyunsaturated fatty acids in lepromatous leprosy: potential markers for susceptibility and pathogenesis
R Al-Mubarak, J Vander Heiden, CD Broeckling, M Balagon, PJ Brennan, ...
PLoS neglected tropical diseases 5 (9), e1303, 2011
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
T Sun, Z Huang, WC Liang, J Yin, WY Lin, J Wu, JM Vernes, J Lutman, ...
Science translational medicine 13 (605), eabe0407, 2021
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