Leona D. Samson
Leona D. Samson
Professor Emerita, Biological Engineering, Biology MIT
Verified email at
Cited by
Cited by
The Lancet Commission on pollution and health
PJ Landrigan, R Fuller, NJR Acosta, O Adeyi, R Arnold, AB Baldé, ...
The lancet 391 (10119), 462-512, 2018
A new pathway for DNA repair in Escherichia coli
L Samson, J Cairns
Nature 267 (5608), 281-283, 1977
Balancing repair and tolerance of DNA damage caused by alkylating agents
D Fu, JA Calvo, LD Samson
Nature Reviews Cancer 12 (2), 104-120, 2012
Systematic discovery of in vivo phosphorylation networks
R Linding, LJ Jensen, GJ Ostheimer, MATM van Vugt, C Jørgensen, ...
Cell 129 (7), 1415-1426, 2007
Standardizing global gene expression analysis between laboratories and across platforms
Toxicogenomics Research Consortium Weis BK weis@ niehs. nih. gov 1 b
Nature methods 2 (5), 351-356, 2005
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
LB Meira, JM Bugni, SL Green, CW Lee, B Pang, D Borenshtein, ...
The Journal of clinical investigation 118 (7), 2516-2525, 2008
Global response of Saccharomyces cerevisiae to an alkylating agent
SA Jelinsky, LD Samson
Proceedings of the National Academy of Sciences 96 (4), 1486-1491, 1999
Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes
SA Jelinsky, P Estep, GM Church, LD Samson
Molecular and cellular biology 20 (21), 8157-8167, 2000
Base excision repair in yeast and mammals
A Memisoglu, L Samson
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 451 (1 …, 2000
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
MJ Hickman, LD Samson
Proceedings of the National Academy of Sciences 96 (19), 10764-10769, 1999
A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction
A Sivaraman, JK Leach, S Townsend, T Iida, BJ Hogan, DB Stolz, R Fry, ...
Current drug metabolism 6 (6), 569-591, 2005
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision
AY Lau, OD Schärer, L Samson, GL Verdine, T Ellenberger
Cell 95 (2), 249-258, 1998
A systems approach to mapping DNA damage response pathways
CT Workman, HC Mak, S McCuine, JB Tagne, M Agarwal, O Ozier, ...
Science 312 (5776), 1054-1059, 2006
The human gut bacterial genotoxin colibactin alkylates DNA
MR Wilson, Y Jiang, PW Villalta, A Stornetta, PD Boudreau, A Carrá, ...
Science 363 (6428), eaar7785, 2019
ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
J Shen, Z Ju, W Zhao, L Wang, Y Peng, Z Ge, ZD Nagel, J Zou, C Wang, ...
Nature medicine 24 (5), 556-562, 2018
Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase
BP Engelward, G Weeda, MD Wyatt, JLM Broekhof, J De Wit, I Donker, ...
Proceedings of the National Academy of Sciences 94 (24), 13087-13092, 1997
Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines
L Samson, JL Schwartz
Nature 287 (5785), 861-863, 1980
An adaptive response of E. coli to low levels of alkylating agent: comparison with previously characterised DNA repair pathways
P Jeggo, M Defais, L Samson, P Schendel
Molecular and General Genetics MGG 157 (1), 1-9, 1977
Activation of inflammation/NF-κB signaling in infants born to arsenic-exposed mothers
RC Fry, P Navasumrit, C Valiathan, JP Svensson, BJ Hogan, M Luo, ...
PLoS genetics 3 (11), e207, 2007
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG
AY Lau, MD Wyatt, BJ Glassner, LD Samson, T Ellenberger
Proceedings of the National Academy of Sciences 97 (25), 13573-13578, 2000
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