| Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells T Seki, S Yuasa, M Oda, T Egashira, K Yae, D Kusumoto, H Nakata, ... Cell stem cell 7 (1), 11-14, 2010 | 714 | 2010 |
| HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle MA Deardorff, M Bando, R Nakato, E Watrin, T Itoh, M Minamino, K Saitoh, ... Nature 489 (7415), 313-317, 2012 | 641 | 2012 |
| De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy T Mashima, H Seimiya, T Tsuruo British journal of cancer 100 (9), 1369-1372, 2009 | 608 | 2009 |
| ATP citrate lyase: activation and therapeutic implications in non–small cell lung cancer T Migita, T Narita, K Nomura, E Miyagi, F Inazuka, M Matsuura, ... Cancer research 68 (20), 8547-8554, 2008 | 440 | 2008 |
| Involvement of 14‐3‐3 proteins in nuclear localization of telomerase H Seimiya, H Sawada, Y Muramatsu, M Shimizu, K Ohko, K Yamane, ... The EMBO journal, 2000 | 427 | 2000 |
| Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins I Naasani, H Seimiya, T Tsuruo Biochemical and Biophysical Research Communications 249 (2), 391-396, 1998 | 361 | 1998 |
| G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in … H Tahara, K Shin-Ya, H Seimiya, H Yamada, T Tsuruo, T Ide Oncogene 25 (13), 1955-1966, 2006 | 267 | 2006 |
| c-Jun NH2-terminal kinase-mediated activation of interleukin-1β converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis H Seimiya, T Mashima, M Toho, T Tsuruo Journal of Biological Chemistry 272 (7), 4631-4636, 1997 | 260 | 1997 |
| ASK1 mediates apoptotic cell death induced by genotoxic stress Z Chen, H Seimiya, M Naito, T Mashima, A Kizaki, S Dan, M Imaizumi, ... Oncogene 18 (1), 173-180, 1999 | 223 | 1999 |
| FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis I Naasani, H Seimiya, T Yamori, T Tsuruo Cancer Research 59 (16), 4004-4011, 1999 | 219 | 1999 |
| Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics H Seimiya, Y Muramatsu, T Ohishi, T Tsuruo Cancer cell 7 (1), 25-37, 2005 | 186 | 2005 |
| The telomeric poly (ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase … H Seimiya, S Smith Journal of Biological Chemistry 277 (16), 14116-14126, 2002 | 184 | 2002 |
| Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-199 H Seimiya, T Oh-hara, T Suzuki, I Naasani, T Shimazaki, K Tsuchiya, ... Molecular cancer therapeutics 1 (9), 657-665, 2002 | 174 | 2002 |
| Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer T Motiwala, H Kutay, K Ghoshal, S Bai, H Seimiya, T Tsuruo, S Suster, ... Proceedings of the National Academy of Sciences 101 (38), 13844-13849, 2004 | 147 | 2004 |
| Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb T Miyazaki, Y Pan, K Joshi, D Purohit, B Hu, H Demir, S Mazumder, ... Clinical Cancer Research 18 (5), 1268-1280, 2012 | 133 | 2012 |
| Revisiting telomere shortening in cancer K Okamoto, H Seimiya Cells 8 (2), 107, 2019 | 128 | 2019 |
| Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells H Seimiya, M Tanji, T Oh-hara, A Tomida, I Naasani, T Tsuruo Biochemical and biophysical research communications 260 (2), 365-370, 1999 | 120 | 1999 |
| Functional subdomain in the ankyrin domain of tankyrase 1 required for poly (ADP-ribosyl) ation of TRF1 and telomere elongation H Seimiya, Y Muramatsu, S Smith, T Tsuruo Molecular and Cellular Biology 24 (5), 1944-1955, 2004 | 110 | 2004 |
| The telomeric PARP, tankyrases, as targets for cancer therapy H Seimiya British journal of cancer 94 (3), 341-345, 2006 | 106 | 2006 |
| Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo K Hirashima, H Seimiya Nucleic acids research 43 (4), 2022-2032, 2015 | 88 | 2015 |
