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Huajun Jin
Huajun Jin
Verified email at iastate.edu
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Year
Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes
H Jin, A Kanthasamy, A Ghosh, V Anantharam, B Kalyanaraman, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014
3792014
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease
S Sarkar, E Malovic, DS Harishchandra, S Ghaisas, N Panicker, A Charli, ...
npj Parkinson's Disease 3 (1), 30, 2017
2182017
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia
N Panicker, S Sarkar, DS Harischandra, M Neal, TI Kam, H Jin, ...
Journal of Experimental Medicine 216 (6), 1411-1430, 2019
1942019
α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity
H Jin, A Kanthasamy, A Ghosh, Y Yang, V Anantharam, AG Kanthasamy
Journal of Neuroscience 31 (6), 2035-2051, 2011
1922011
Manganese-induced neurotoxicity: new insights into the triad of protein misfolding, mitochondrial impairment, and neuroinflammation
DS Harischandra, S Ghaisas, G Zenitsky, H Jin, A Kanthasamy, ...
Frontiers in Neuroscience 13, 654, 2019
1862019
Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark …
M Ay, J Luo, M Langley, H Jin, V Anantharam, A Kanthasamy, ...
Journal of neurochemistry 141 (5), 766-782, 2017
1632017
Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease
N Panicker, H Saminathan, H Jin, M Neal, DS Harischandra, R Gordon, ...
Journal of Neuroscience 35 (27), 10058-10077, 2015
1482015
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein
DS Harischandra, D Rokad, ML Neal, S Ghaisas, S Manne, S Sarkar, ...
Science signaling 12 (572), eaau4543, 2019
1452019
Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration
C Song, A Kanthasamy, H Jin, V Anantharam, AG Kanthasamy
Neurotoxicology 32 (5), 586-595, 2011
1422011
Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes
S Sarkar, E Malovic, DS Harischandra, HA Ngwa, A Ghosh, C Hogan, ...
Neurotoxicology 64, 204-218, 2018
1212018
Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases
HE Gendelman, V Anantharam, T Bronich, S Ghaisas, H Jin, ...
Nanomedicine: Nanotechnology, Biology and Medicine 11 (3), 751-767, 2015
1202015
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
S Sarkar, D Rokad, E Malovic, J Luo, DS Harischandra, H Jin, ...
Science Signaling 12 (563), eaat9900, 2019
1152019
Mito-apocynin prevents mitochondrial dysfunction, microglial activation, oxidative damage, and progressive neurodegeneration in MitoPark transgenic mice
M Langley, A Ghosh, A Charli, S Sarkar, M Ay, J Luo, J Zielonka, T Brenza, ...
Antioxidants & redox signaling 27 (14), 1048-1066, 2017
1132017
α‐Synuclein real‐time quaking‐induced conversion in the submandibular glands of Parkinson's disease patients
S Manne, N Kondru, H Jin, V Anantharam, X Huang, A Kanthasamy, ...
Movement Disorders 35 (2), 268-278, 2020
1102020
Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes
M Neal, J Luo, DS Harischandra, R Gordon, S Sarkar, H Jin, ...
Glia 66 (10), 2137-2157, 2018
1012018
Blinded RT‐QuIC analysis of α‐Synuclein biomarker in skin tissue from Parkinson's disease patients
S Manne, N Kondru, H Jin, GE Serrano, V Anantharam, A Kanthasamy, ...
Movement Disorders 35 (12), 2230-2239, 2020
992020
Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in …
M Lin, P Chandramani-Shivalingappa, H Jin, A Ghosh, V Anantharam, ...
Neuroscience 210, 308-332, 2012
992012
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease
R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ...
Neurobiology of disease 93, 96-114, 2016
982016
Mitoapocynin treatment protects against neuroinflammation and dopaminergic neurodegeneration in a preclinical animal model of Parkinson’s disease
A Ghosh, MR Langley, DS Harischandra, ML Neal, H Jin, V Anantharam, ...
Journal of Neuroimmune Pharmacology 11, 259-278, 2016
952016
α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson’s disease
DS Harischandra, H Jin, V Anantharam, A Kanthasamy, AG Kanthasamy
Toxicological Sciences 143 (2), 454-468, 2015
952015
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