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Deborah R Caswell
Deborah R Caswell
Post-doctoral Scholar, Francis Crick Institute
Verified email at crick.ac.uk
Title
Cited by
Cited by
Year
Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress
RG al.
Cell, 2014
4722014
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
SH Chiou, IP Winters, J Wang, S Naranjo, C Dudgeon, FB Tamburini, ...
Genes & development 29 (14), 1576-1585, 2015
2672015
The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome
DR Caswell, C Swanton
BMC medicine 15, 1-9, 2017
2192017
Lung adenocarcinoma promotion by air pollutants
W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ...
Nature 616 (7955), 159-167, 2023
1992023
Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis
CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ...
Nature medicine 23 (3), 291-300, 2017
1522017
An Arntl2-driven secretome enables lung adenocarcinoma metastatic self-sufficiency
JJ Brady, CH Chuang, PG Greenside, ZN Rogers, CW Murray, ...
Cancer cell 29 (5), 697-710, 2016
932016
The neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis
S KW, K C, B KJ, L Jaewon, L AN, L KT, Z P, B AM, F CM, C DR, et al.
PNAS, 2014
90*2014
Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution
S Venkatesan, M Angelova, C Puttick, H Zhai, DR Caswell, WT Lu, ...
Cancer discovery 11 (10), 2456-2473, 2021
872021
Obligate progression precedes lung adenocarcinoma dissemination
DR Caswell, CH Chuang, D Yang, SH Chiou, S Cheemalavagu, ...
Cancer discovery 4 (7), 781-789, 2014
562014
Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma
PN Valdmanis, B Roy-Chaudhuri, HK Kim, LC Sayles, Y Zheng, ...
Oncogene 34 (1), 94-103, 2015
532015
Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, Suppresses Lung Cancer
DR Caswell, CH Chuang, RK Ma, IP Winters, EL Snyder, MM Winslow
Molecular Cancer Research 16 (11), 1737-1749, 2018
35*2018
An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations
J Boumelha, S de Carné Trécesson, EK Law, P Romero-Clavijo, ...
Cancer research 82 (19), 3435-3448, 2022
302022
Capturing cancer evolution using genetically engineered mouse models (GEMMs)
W Hill, DR Caswell, C Swanton
Trends in Cell Biology 31 (12), 1007-1018, 2021
242021
Targeted cancer therapy induces APOBEC fueling the evolution of drug resistance
M Mayekar, D Caswell, N Vokes, EK Law, W Wu, W Hill, E Gronroos, ...
Cancer Research 82 (12_Supplement), 2197-2197, 2022
182022
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance
DR Caswell, P Gui, MK Mayekar, EK Law, O Pich, C Bailey, J Boumelha, ...
Nature Genetics 56 (1), 60-73, 2024
112024
APOBEC3B expression generates an immunogenic model of Kras mutant lung cancer
S de Carné Trécesson, J Boumelha, EK Law, P Romero-Clavijo, ...
BioRxiv, 2020.2012. 2022.423126, 2020
62020
Non-Small-Cell Lung Cancer Promotion by Air Pollutants
C Swanton, W Hill, E Lim, C Lee, C Weeden, M Augustine, K Chen, ...
32022
Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors
JL Reading, DR Caswell, C Swanton
Nature Genetics 55 (10), 1610-1612, 2023
22023
The role of APOBEC3B in lung tumour evolution and targeted therapy resistance
DR Caswell, MK Mayekar, P Gui, EK Law, NI Vokes, CM Ruiz, M Dietzen, ...
bioRxiv, 2020.12. 18.423280, 2020
22020
An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations
J Boumelha, S de Carné Trécesson, EK Law, P Romero-Clavijo, ...
bioRxiv, 2020.12. 22.423126, 2020
12020
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