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Goran Malojcic, PhD
Goran Malojcic, PhD
Harvard University
Verified email at alumni.ethz.ch
Title
Cited by
Cited by
Year
LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface
G Malojčić, D Andres, M Grabowicz, AH George, N Ruiz, TJ Silhavy, ...
Proceedings of the National Academy of Sciences 111 (26), 9467-9472, 2014
872014
DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli
JPA Grimshaw, CU Stirnimann, MS Brozzo, G Malojcic, MG Grütter, ...
Journal of molecular biology 380 (4), 667-680, 2008
872008
Structural basis of substrate specificity of human oligosaccharyl transferase subunit N33/Tusc3 and its role in regulating protein N-glycosylation
E Mohorko, RL Owen, G Malojčić, MS Brozzo, M Aebi, R Glockshuber
Structure 22 (4), 590-601, 2014
842014
A novel bis-phenanthridine triamine with pH controlled binding to nucleotides and nucleic acids
G Malojčić, I Piantanida, M Marinić, M Žinić, M Marjanović, M Kralj, ...
Organic & biomolecular chemistry 3 (24), 4373-4381, 2005
632005
A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli
G Malojčić, RL Owen, JPA Grimshaw, MS Brozzo, H Dreher-Teo, ...
Proceedings of the National Academy of Sciences 105 (49), 19217-19222, 2008
562008
A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa
G Andolina, LC Bencze, K Zerbe, M Müller, J Steinmann, H Kocherla, ...
ACS chemical biology 13 (3), 666-675, 2018
552018
Oxidative folding of peptides and proteins
L Moroder, J Buchner
Royal society of chemistry, 2009
48*2009
Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB
G Malojčić, RL Owen, JPA Grimshaw, R Glockshuber
FEBS letters 582 (23-24), 3301-3307, 2008
382008
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription
JK Rimel, ZC Poss, B Erickson, ZL Maas, CC Ebmeier, JL Johnson, ...
Genes & development 34 (21-22), 1452-1473, 2020
342020
The PAPS-independent aryl sulfotransferase and the alternative disulfide bond formation system in pathogenic bacteria
G Malojčić, R Glockshuber
Antioxidants & redox signaling 13 (8), 1247-1259, 2010
332010
Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
D Vinayagam, D Quentin, J Yu-Strzelczyk, O Sitsel, F Merino, M Stabrin, ...
Elife 9, e60603, 2020
272020
Discovery of a potent and selective TRPC5 inhibitor, efficacious in a focal segmental glomerulosclerosis model
M Yu, MW Ledeboer, M Daniels, G Malojcic, TT Tibbitts, M Coeffet-Le Gal, ...
ACS medicinal chemistry letters 10 (11), 1579-1585, 2019
272019
A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface
M Grabowicz, D Andres, MD Lebar, G Malojčić, D Kahne, TJ Silhavy
Elife 3, e05334, 2014
202014
Structural and mechanistic insights into the PAPS-independent sulfotransfer catalyzed by bacterial aryl sulfotransferase and the role of the DsbL/DsbI system in its folding
G Malojcic, RL Owen, R Glockshuber
Biochemistry 53 (11), 1870-1877, 2014
202014
Discovery of SY-5609: a selective, noncovalent inhibitor of CDK7
JJ Marineau, KB Hamman, S Hu, S Alnemy, J Mihalich, A Kabro, ...
Journal of Medicinal Chemistry 65 (2), 1458-1480, 2021
112021
Mechanism of the prokaryotic transmembrane disulfide reduction pathway and its in vitro reconstitution from purified components
G Malojčić, ER Geertsma, MS Brozzo, R Glockshuber
Angewandte Chemie International Edition 51 (28), 6900-6903, 2012
42012
A translational kidney organoid system bolsters human relevance of clinical development candidate
A Westerling-Bui, TW Soare, S Venkatachalan, M DeRan, EM Fast, ...
bioRxiv, 2019
32019
Targeting the transcriptional kinases CDK12 and CDK13 in breast and ovarian cancer
K Hamman, M Bradley, J Marineau, Y Choi, G Malojcic, D Orlando, Y Ren, ...
The FASEB Journal 31, 938.9-938.9, 2017
32017
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic
AD Westerling-Bui, EM Fast, TW Soare, S Venkatachalan, M DeRan, ...
Science advances 8 (27), eabj5633, 2022
22022
Discovery and Optimization of Highly Selective Inhibitors of CDK5
MH Daniels, G Malojcic, SL Clugston, B Williams, M Coeffet-Le Gal, ...
Journal of Medicinal Chemistry 65 (4), 3575-3596, 2022
22022
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