| Cancer cells display profound intra-and interline variation following prolonged exposure to antimitotic drugs KE Gascoigne, SS Taylor Cancer cell 14 (2), 111-122, 2008 | 909 | 2008 |
| How do anti-mitotic drugs kill cancer cells? KE Gascoigne, SS Taylor Journal of cell science 122 (15), 2579-2585, 2009 | 470 | 2009 |
| Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes KE Gascoigne, K Takeuchi, A Suzuki, T Hori, T Fukagawa, IM Cheeseman Cell 145 (3), 410-422, 2011 | 395 | 2011 |
| Validating Aurora B as an anti-cancer drug target F Girdler, KE Gascoigne, PA Eyers, S Hartmuth, C Crafter, KM Foote, ... Journal of cell science 119 (17), 3664-3675, 2006 | 350 | 2006 |
| Enhancer activity requires CBP/P300 bromodomain-dependent histone H3K27 acetylation R Raisner, S Kharbanda, L Jin, E Jeng, E Chan, M Merchant, PM Haverty, ... Cell reports 24 (7), 1722-1729, 2018 | 291 | 2018 |
| CENP-TWSX forms a unique centromeric chromatin structure with a histone-like fold T Nishino, K Takeuchi, KE Gascoigne, A Suzuki, T Hori, T Oyama, ... Cell 148 (3), 487-501, 2012 | 284 | 2012 |
| Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T F Rago, KE Gascoigne, IM Cheeseman Current Biology 25 (5), 671-677, 2015 | 150 | 2015 |
| Therapeutic targeting of the CBP/p300 bromodomain blocks the growth of castration-resistant prostate cancer L Jin, J Garcia, E Chan, C de la Cruz, E Segal, M Merchant, S Kharbanda, ... Cancer research 77 (20), 5564-5575, 2017 | 134 | 2017 |
| Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity TH Pillow, P Adhikari, RA Blake, J Chen, G Del Rosario, G Deshmukh, ... ChemMedChem 15 (1), 17-25, 2020 | 116 | 2020 |
| Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma AR Conery, RC Centore, A Neiss, PJ Keller, S Joshi, KL Spillane, ... Elife 5, e10483, 2016 | 111 | 2016 |
| CDK-dependent phosphorylation and nuclear exclusion coordinately control kinetochore assembly state KE Gascoigne, IM Cheeseman Journal of Cell Biology 201 (1), 23-32, 2013 | 108 | 2013 |
| GNE-781, a highly advanced potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein, binding protein (CBP) FA Romero, J Murray, KW Lai, V Tsui, BK Albrecht, L An, MH Beresini, ... Journal of Medicinal Chemistry 60 (22), 9162-9183, 2017 | 92 | 2017 |
| Discovery of a potent and selective in vivo probe (GNE-272) for the bromodomains of CBP/EP300 TD Crawford, FA Romero, KW Lai, V Tsui, AM Taylor, G de Leon Boenig, ... Journal of medicinal chemistry 59 (23), 10549-10563, 2016 | 89 | 2016 |
| Antibody-mediated delivery of chimeric BRD4 degraders. Part 1: exploration of antibody linker, payload loading, and payload molecular properties PS Dragovich, TH Pillow, RA Blake, JD Sadowsky, E Adaligil, P Adhikari, ... Journal of Medicinal Chemistry 64 (5), 2534-2575, 2021 | 87 | 2021 |
| Kinetochore assembly: if you build it, they will come KE Gascoigne, IM Cheeseman Current opinion in cell biology 23 (1), 102-108, 2011 | 85 | 2011 |
| Induced dicentric chromosome formation promotes genomic rearrangements and tumorigenesis KE Gascoigne, IM Cheeseman Chromosome research 21, 407-418, 2013 | 72 | 2013 |
| Regulation of tumor-associated myeloid cell activity by CBP/EP300 bromodomain modulation of H3K27 acetylation DE de Almeida Nagata, EY Chiang, S Jhunjhunwala, P Caplazi, ... Cell Reports 27 (1), 269-281. e4, 2019 | 46 | 2019 |
| The ETS domain transcription factor Elk-1 regulates the expression of its partner protein, SRF A Kasza, A O'Donnell, K Gascoigne, LAH Zeef, A Hayes, AD Sharrocks Journal of Biological Chemistry 280 (2), 1149-1155, 2005 | 46 | 2005 |
| An antibody–drug conjugate directed against lymphocyte antigen 6 complex, locus E (LY6E) provides robust tumor killing in a wide range of solid tumor malignancies J Asundi, L Crocker, J Tremayne, P Chang, C Sakanaka, J Tanguay, ... Clinical Cancer Research 21 (14), 3252-3262, 2015 | 38 | 2015 |
| Repeated Sequences in CASPASE-5 and FANCD2 but not NF1 Are Targets for Mutation in Microsatellite-Unstable Acute Leukemia/Myelodysplastic Syndrome J Offman, K Gascoigne, F Bristow, P Macpherson, M Bignami, I Casorelli, ... Molecular cancer research 3 (5), 251-260, 2005 | 38 | 2005 |
