| The hallmarks of aging C López-Otín, MA Blasco, L Partridge, M Serrano, G Kroemer Cell 153 (6), 1194-1217, 2013 | 14121 | 2013 |
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a M Serrano, AW Lin, ME McCurrach, D Beach, SW Lowe Cell 88 (5), 593-602, 1997 | 5925 | 1997 |
| A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 M Serrano, GJ Hannon, D Beach nature 366 (6456), 704-707, 1993 | 5523 | 1993 |
| Cellular senescence: from physiology to pathology D Muñoz-Espín, M Serrano Nature reviews Molecular cell biology 15 (7), 482-496, 2014 | 2527 | 2014 |
| Cellular senescence in cancer and aging M Collado, MA Blasco, M Serrano Cell 130 (2), 223-233, 2007 | 2031 | 2007 |
| Role of the INK4a locus in tumor suppression and cell mortality M Serrano, HW Lee, L Chin, C Cordon-Cardo, D Beach, RA DePinho Cell 85 (1), 27-37, 1996 | 1964 | 1996 |
| Cellular senescence: defining a path forward V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ... Cell 179 (4), 813-827, 2019 | 1797 | 2019 |
| Senescence in premalignant tumours M Collado, J Gil, A Efeyan, C Guerra, AJ Schuhmacher, M Barradas, ... Nature 436 (7051), 642-642, 2005 | 1755 | 2005 |
| A p16INK4a-Insensitive CDK4 Mutant Targeted by Cytolytic T Lymphocytes in a Human Melanoma T Wölfel, M Hauer, J Schneider, M Serrano, C Wölfel, E Klehmann-Hieb, ... Science 269 (5228), 1281-1284, 1995 | 1509 | 1995 |
| Programmed cell senescence during mammalian embryonic development D Muñoz-Espín, M Cañamero, A Maraver, G Gómez-López, J Contreras, ... Cell 155 (5), 1104-1118, 2013 | 1359 | 2013 |
| Senescence in tumours: evidence from mice and humans M Collado, M Serrano Nature Reviews Cancer 10 (1), 51-57, 2010 | 1311 | 2010 |
| The common biology of cancer and ageing T Finkel, M Serrano, MA Blasco Nature 448 (7155), 767-774, 2007 | 1225 | 2007 |
| A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity RM Marión, K Strati, H Li, M Murga, R Blanco, S Ortega, ... Nature 460 (7259), 1149-1153, 2009 | 1217 | 2009 |
| Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling AW Lin, M Barradas, JC Stone, L Van Aelst, M Serrano, SW Lowe Genes & development 12 (19), 3008-3019, 1998 | 1189 | 1998 |
| Hallmarks of aging: An expanding universe C López-Otín, MA Blasco, L Partridge, M Serrano, G Kroemer Cell 186 (2), 243-278, 2023 | 1143 | 2023 |
| The Ink4/Arf locus is a barrier for iPS cell reprogramming H Li, M Collado, A Villasante, K Strati, S Ortega, M Cañamero, MA Blasco, ... Nature 460 (7259), 1136-1139, 2009 | 1131 | 2009 |
| Sirt1 protects against high-fat diet-induced metabolic damage PT Pfluger, D Herranz, S Velasco-Miguel, M Serrano, MH Tschöp Proceedings of the national academy of sciences 105 (28), 9793-9798, 2008 | 1111 | 2008 |
| Mutations and altered expression of p16INK4 in human cancer. A Okamoto, DJ Demetrick, EA Spillare, K Hagiwara, SP Hussain, ... Proceedings of the National Academy of Sciences 91 (23), 11045-11049, 1994 | 880 | 1994 |
| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 852 | 2022 |
| p19ARF links the tumour suppressor p53 to Ras I Palmero, C Pantoja, M Serrano Nature 395 (6698), 125-126, 1998 | 812 | 1998 |
