Signaling specificity in the Akt pathway in biology and disease A Toker, S Marmiroli Advances in biological regulation 55, 28-38, 2014 | 221 | 2014 |
Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity—Diverse effects on cell growth, metabolism and cancer JA McCubrey, D Rakus, A Gizak, LS Steelman, SL Abrams, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (12), 2942-2976, 2016 | 174 | 2016 |
Development of solvent-casting particulate leaching (SCPL) polymer scaffolds as improved three-dimensional supports to mimic the bone marrow niche A Sola, J Bertacchini, D D'Avella, L Anselmi, T Maraldi, S Marmiroli, ... Materials Science and Engineering: C 96, 153-165, 2019 | 151 | 2019 |
The need for a reassessment of the safe upper limit of selenium in drinking water M Vinceti, CM Crespi, F Bonvicini, C Malagoli, M Ferrante, S Marmiroli, ... Science of the Total Environment 443, 633-642, 2013 | 137 | 2013 |
Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts G Lattanzi, V Cenni, S Marmiroli, C Capanni, E Mattioli, L Merlini, ... Biochemical and biophysical research communications 303 (3), 764-770, 2003 | 116 | 2003 |
Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria V Cenni, C Capanni, M Columbaro, M Ortolani, MR D'Apice, G Novelli, ... European journal of histochemistry: EJH 55 (4), 2011 | 107 | 2011 |
Targeting of the Akt/PKB kinase to the actin skeleton V Cenni, A Sirri, M Riccio, G Lattanzi, S Santi, A de Pol, NM Maraldi, ... Cellular and Molecular Life Sciences CMLS 60, 2710-2720, 2003 | 107 | 2003 |
Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level G Di Maira, F Brustolon, J Bertacchini, K Tosoni, S Marmiroli, LA Pinna, ... Oncogene 26 (48), 6915-6926, 2007 | 105 | 2007 |
Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells. S Marmiroli, A Ognibene, A Bavelloni, C Cinti, L Cocco, NM Maraldi Journal of Biological Chemistry 269 (1), 13-16, 1994 | 94 | 1994 |
Targeting PI3K/Akt/mTOR in AML: rationale and clinical evidence S Darici, H Alkhaldi, G Horne, HG Jørgensen, S Marmiroli, X Huang Journal of Clinical Medicine 9 (9), 2934, 2020 | 92 | 2020 |
Lamin A Ser404 is a nuclear target of Akt phosphorylation in C2C12 cells V Cenni, J Bertacchini, F Beretti, G Lattanzi, A Bavelloni, M Riccio, ... Journal of proteome research 7 (11), 4727-4735, 2008 | 90 | 2008 |
Tumour necrosis factor‐related apoptosis‐inducing ligand sequentially activates pro‐survival and pro‐apoptotic pathways in SK‐N‐MC neuronal cells D Milani, G Zauli, E Rimondi, C Celeghini, S Marmiroli, P Narducci, ... Journal of neurochemistry 86 (1), 126-135, 2003 | 90 | 2003 |
Phosphatidylinositol 3‐kinase is recruited to a specific site in the activated IL‐1 receptor I S Marmiroli, A Bavelloni, I Faenza, A Sirri, A Ognibene, V Cenni, ... FEBS letters 438 (1-2), 49-54, 1998 | 90 | 1998 |
AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation AS Naeem, Y Zhu, WL Di, S Marmiroli, RFL O'shaughnessy Cell Death & Differentiation 22 (12), 2123-2132, 2015 | 84 | 2015 |
The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression J Bertacchini, F Beretti, V Cenni, M Guida, F Gibellini, L Mediani, O Marin, ... The FASEB Journal 27 (6), 2145-2155, 2013 | 82 | 2013 |
Deregulated PTEN/PI3K/AKT/mTOR signaling in prostate cancer: still a potential druggable target? L Braglia, M Zavatti, M Vinceti, AM Martelli, S Marmiroli Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (9), 118731, 2020 | 75 | 2020 |
Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis J Bertacchini, M Guida, B Accordi, L Mediani, AM Martelli, P Barozzi, ... Leukemia 28 (11), 2197-2205, 2014 | 73 | 2014 |
Phosphatidylinositol 3-kinase translocation to the nucleus is induced by interleukin 1 and prevented by mutation of interleukin 1 receptor in human osteosarcoma Saos-2 cells A Bavelloni, S Santi, A Sirri, M Riccio, I Faenza, N Zini, S Cecchi, A Ferri, ... Journal of cell science 112 (5), 631-640, 1999 | 72 | 1999 |
Lamin A N-terminal phosphorylation is associated with myoblast activation: impairment in Emery–Dreifuss muscular dystrophy V Cenni, P Sabatelli, E Mattioli, S Marmiroli, C Capanni, A Ognibene, ... Journal of medical genetics 42 (3), 214-220, 2005 | 67 | 2005 |
Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer C Evangelisti, F Chiarini, F Paganelli, S Marmiroli, AM Martelli Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (4), 118635, 2020 | 62 | 2020 |