|Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity|
F Borges, F Roleira, N Milhazes, L Santana, E Uriarte
Current medicinal chemistry 12 (8), 887-916, 2005
|Phenolic acid derivatives with potential anticancer properties––a structure–activity relationship study. Part 1: Methyl, propyl and octyl esters of caffeic and gallic acids|
SM Fiuza, C Gomes, LJ Teixeira, MTG Da Cruz, M Cordeiro, N Milhazes, ...
Bioorganic & medicinal chemistry 12 (13), 3581-3589, 2004
|Anticancer activity of phenolic acids of natural or synthetic origin: a structure− activity study|
CA Gomes, T Girão da Cruz, JL Andrade, N Milhazes, F Borges, ...
Journal of medicinal chemistry 46 (25), 5395-5401, 2003
|Chromone as a privileged scaffold in drug discovery: recent advances: miniperspective|
J Reis, A Gaspar, N Milhazes, F Borges
Journal of medicinal chemistry 60 (19), 7941-7957, 2017
|Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity|
L Santana, E Uriarte, F Roleira, N Milhazes, F Borges
Current medicinal chemistry 11 (24), 3239-3261, 2004
|Methamphetamine‐induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin|
J Gonçalves, S Baptista, T Martins, N Milhazes, F Borges, CF Ribeiro, ...
European Journal of Neuroscience 31 (2), 315-326, 2010
|Simple coumarins: Privileged scaffolds in medicinal chemistry|
MFM Borges, FMF Roleira, N Milhazes, EU Villare, LS Penin
Frontiers in Medicinal Chemistry 4, 23-85, 2010
|Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory|
PF Simoes, AP Silva, FC Pereira, E Marques, S Grade, N Milhazes, ...
Neuroscience 150 (2), 433-441, 2007
|Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells|
TL Serafim, FS Carvalho, MPM Marques, R Calheiros, T Silva, J Garrido, ...
Chemical research in toxicology 24 (5), 763-774, 2011
|Methamphetamine‐induced early increase of il‐6 and tnf‐α mrna expression in the mouse brain|
J Gonçalves, T Martins, R Ferreira, N Milhazes, F Borges, CF Ribeiro, ...
Annals of the New York Academy of Sciences 1139 (1), 103-111, 2008
|Methamphetamine transiently increases the blood–brain barrier permeability in the hippocampus: role of tight junction proteins and matrix metalloproteinase-9|
T Martins, S Baptista, J Gonçalves, E Leal, N Milhazes, F Borges, ...
Brain research 1411, 28-40, 2011
|Hepatotoxicity of 3, 4-methylenedioxyamphetamine and α-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates|
M Carvalho, N Milhazes, F Remião, F Borges, E Fernandes, F Amado, ...
Archives of toxicology 78 (1), 16-24, 2004
|Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells|
M Carvalho, G Hawksworth, N Milhazes, F Borges, TJ Monks, ...
Archives of toxicology 76 (10), 581-588, 2002
|Lipophilic phenolic antioxidants: Correlation between antioxidant profile, partition coefficients and redox properties|
FMF Roleira, C Siquet, E Orrù, EM Garrido, J Garrido, N Milhazes, ...
Bioorganic & medicinal chemistry 18 (16), 5816-5825, 2010
|The toxicity of N-methyl-α-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine|
M Carvalho, F Remião, N Milhazes, F Borges, E Fernandes, F Carvalho, ...
Toxicology 200 (2-3), 193-203, 2004
|Structure− property− activity relationship of phenolic acids and derivatives. Protocatechuic acid alkyl esters|
B Reis, M Martins, B Barreto, N Milhazes, EM Garrido, P Silva, J Garrido, ...
Journal of agricultural and food chemistry 58 (11), 6986-6993, 2010
|β-Nitrostyrene derivatives as potential antibacterial agents: A structure–property–activity relationship study|
N Milhazes, R Calheiros, MPM Marques, J Garrido, MNDS Cordeiro, ...
Bioorganic & medicinal chemistry 14 (12), 4078-4088, 2006
|New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives|
A Gaspar, EM Garrido, M Esteves, E Quezada, N Milhazes, J Garrido, ...
European Journal of Medicinal Chemistry 44 (5), 2092-2099, 2009
|Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro|
M Carvalho, F Remiao, N Milhazes, F Borges, E Fernandes, ...
Chemical research in toxicology 17 (5), 623-632, 2004
|Evaluation of the lipophilic properties of opioids, amphetamine-like drugs, and metabolites through electrochemical studies at the interface between two immiscible solutions|
R Gulaboski, MNDS Cordeiro, N Milhazes, J Garrido, F Borges, M Jorge, ...
Analytical biochemistry 361 (2), 236-243, 2007