| Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease DI Lee, G Zhu, T Sasaki, GS Cho, N Hamdani, R Holewinski, SH Jo, ... Nature 519 (7544), 472-476, 2015 | 339 | 2015 |
| Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart P Zhang, JA Kirk, W Ji, CG Dos Remedios, DA Kass, JE Van Eyk, ... Circulation 126 (15), 1828-1837, 2012 | 161 | 2012 |
| Creatine kinase–mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved A Gupta, A Akki, Y Wang, MK Leppo, VP Chacko, DB Foster, V Caceres, ... The Journal of Clinical Investigation 122 (1), 291, 2012 | 143 | 2012 |
| Electromechanical dyssynchrony and resynchronization of the failing heart JA Kirk, DA Kass Circulation research 113 (6), 765-776, 2013 | 128 | 2013 |
| Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction A Ngkelo, A Richart, JA Kirk, P Bonnin, J Vilar, M Lemitre, P Marck, ... Journal of Experimental Medicine 213 (7), 1353-1374, 2016 | 118 | 2016 |
| The role of heat shock proteins and co-chaperones in heart failure MJ Ranek, MJ Stachowski, JA Kirk, MS Willis Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 117 | 2018 |
| Right ventricular myofilament functional differences in humans with systemic sclerosis–associated versus idiopathic pulmonary arterial hypertension S Hsu, KM Kokkonen-Simon, JA Kirk, TM Kolb, RL Damico, SC Mathai, ... Circulation 137 (22), 2360-2370, 2018 | 113 | 2018 |
| Thrombospondin-4 Is Required for Stretch-Mediated Contractility Augmentation in Cardiac Muscle OH Cingolani, JA Kirk, K Seo, N Koitabashi, D Lee, G Ramirez-Correa, ... Circulation research 109 (12), 1410-1414, 2011 | 89 | 2011 |
| Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β JA Kirk, RJ Holewinski, V Kooij, G Agnetti, RS Tunin, N Witayavanitkul, ... The Journal of clinical investigation 124 (1), 129-139, 2014 | 87 | 2014 |
| Desmin modifications associate with amyloid-like oligomers deposition in heart failure G Agnetti, VL Halperin, JA Kirk, K Chakir, Y Guo, L Lund, F Nicolini, ... Cardiovascular research 102 (1), 24-34, 2014 | 78 | 2014 |
| Citrullination of myofilament proteins in heart failure J Fert-Bober, JT Giles, RJ Holewinski, JA Kirk, H Uhrigshardt, EL Crowgey, ... Cardiovascular research 108 (2), 232-242, 2015 | 77 | 2015 |
| Guidelines for in vivo mouse models of myocardial infarction ML Lindsey, KR Brunt, JA Kirk, P Kleinbongard, JW Calvert, ... American Journal of Physiology-Heart and Circulatory Physiology, 2021 | 75 | 2021 |
| Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover TG Martin, VD Myers, P Dubey, S Dubey, E Perez, CS Moravec, MS Willis, ... Nature communications 12 (1), 2942, 2021 | 72 | 2021 |
| Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I JA Kirk, GA MacGowan, C Evans, SH Smith, CM Warren, R Mamidi, ... Circulation research 105 (12), 1232-1239, 2009 | 72 | 2009 |
| Reinforcing rigor and reproducibility expectations for use of sex and gender in cardiovascular research ML Lindsey, AJ LeBlanc, CM Ripplinger, JR Carter, JA Kirk, ... American Journal of Physiology-Heart and Circulatory Physiology 321 (5 …, 2021 | 69 | 2021 |
| Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice J Naghshin, KR McGaffin, WG Witham, MA Mathier, LC Romano, ... Journal of applied physiology 107 (3), 787-793, 2009 | 69 | 2009 |
| Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function M Papadaki, RJ Holewinski, SB Previs, TG Martin, MJ Stachowski, A Li, ... JCI insight 3 (20), 2018 | 56 | 2018 |
| Under construction: The dynamic assembly, maintenance, and degradation of the cardiac sarcomere TG Martin, JA Kirk Journal of molecular and cellular cardiology 148, 89-102, 2020 | 52 | 2020 |
| Sunitinib causes dose‐dependent negative functional effects on myocardium and cardiomyocytes PP Rainer, B Doleschal, JA Kirk, V Sivakumaran, Z Saad, K Groschner, ... BJU international, 2012 | 52 | 2012 |
| Thrombospondins in the transition from myocardial infarction to heart failure JA Kirk, OH Cingolani Journal of molecular and cellular cardiology 90, 102-110, 2016 | 42 | 2016 |
David A. KassJohns Hopkins UniversityVerified email at jhmi.edu
