Joseph Aslan

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Owen JT McCartyProfessor of Biomedical Engineering, Oregon Health & Science UniversityVerified email at ohsu.edu
Joseph ShatzelOregon Health & Science UniversityVerified email at ohsu.edu
Rachel A. RiggPhD student, Department of Biomedical Engineering, Oregon Health & Science UniversityVerified email at ohsu.edu
Iván Parra IzquierdoSenior Scientist at Boehringer IngelheimVerified email at boehringer-ingelheim.com
Cassandra P. LorenResearcher, Oregon Health & Science UniversityVerified email at ohsu.edu
Monica T HindsOregon Health & Science UniversityVerified email at ohsu.edu
Larry DavidProfessor of Biochemistry and Molecular Biology, Oregon Health & Science UniversityVerified email at ohsu.edu
Alexander Robert MelroseSenior Research Assistant, Oregon Health & Science UniversityVerified email at ohsu.edu
Anh T. P. NgoPostdoctoral Fellow | Host-Microbe Systems & Therapeutics | University of California San DiegoVerified email at health.ucsd.edu
asako itakuraOregon Health & Science UniversityVerified email at ohsu.edu
Özgün BaburAssistant Professor at University of Massachusetts BostonVerified email at umb.edu
Laura D HealyPostdoctoral Researcher, The Scripps Research Institute, Oregon Health & Science UniversityVerified email at scripps.edu
Andras GruberAronora, Inc.Verified email at aronorabio.com
Tony J. ZhengOregon Health & Science UniversityVerified email at ohsu.edu
Emek DemirOHSUVerified email at ohsu.edu
Thomas SimmenUniversity of AlbertaVerified email at ualberta.ca
Jonathan ChernoffFox Chase Cancer CenterVerified email at fccc.edu
Hari Hara Sudhan LakshmananOregon Health and Science UniversityVerified email at mix.wvu.edu
Annachiara MitrugnoPostdoctoral Fellow, Oregon Health and Science UniversityVerified email at ohsu.edu
Kylee MartensHematology & Oncology, Oregon Health and Science UniversityVerified email at ohsu.edu

Joseph Aslan

Associate Professor, Knight Cardiovascular Institute, Oregon Health & Science University

Verified email at ohsu.edu - Homepage

Platelets Proteomics Cell Signaling Cell Biology Cardiovascular Disease


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PACS-2 controls endoplasmic reticulum–mitochondria communication and Bid-mediated apoptosis T Simmen, JE Aslan, AD Blagoveshchenskaya, L Thomas, L Wan, ... The EMBO journal 24 (4), 717-729, 2005	629	2005
Rho GTPases in platelet function JE Aslan, OJT McCarty Journal of Thrombosis and Haemostasis 11 (1), 35-46, 2013	241	2013
A physical sciences network characterization of non-tumorigenic and metastatic cells Scientific reports 3 (1), 1449, 2013	181	2013
S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation JE Aslan, GW Tormoen, CP Loren, J Pang, OJT McCarty Blood 118 (11), 3129-3136, 2011	143	2011
Platelet shape change and spreading. JE Aslan, A Itakura, JM Gertz, OJ McCarty Methods in molecular biology (Clifton, NJ) 788, 91, 2012	116	2012
The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear CP Loren, JE Aslan, RA Rigg, MS Nowak, LD Healy, A Gruber, BJ Druker, ... Thrombosis research 135 (1), 155-160, 2015	88	2015
Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis JE Aslan, H You, DM Williamson, J Endig, RT Youker, L Thomas, H Shu, ... Molecular cell 34 (4), 497-509, 2009	85	2009
Oral administration of Bruton's tyrosine kinase inhibitors impairs GPVI-mediated platelet function RA Rigg, JE Aslan, LD Healy, M Wallisch, MLD Thierheimer, CP Loren, ... American Journal of Physiology-Cell Physiology 310 (5), C373-C380, 2016	83	2016
Causal interactions from proteomic profiles: Molecular data meet pathway knowledge Ö Babur, A Luna, A Korkut, F Durupinar, MC Siper, U Dogrusoz, ... Patterns 2 (6), 2021	76	2021
Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs Ö Babur, AR Melrose, JM Cunliffe, J Klimek, J Pang, ALI Sepp, ... Blood, The Journal of the American Society of Hematology 136 (20), 2346-2358, 2020	76	2020
The incidence, complications, and treatment of iron deficiency in pregnancy AE Benson, JJ Shatzel, KS Ryan, MA Hedges, K Martens, JE Aslan, JO Lo European journal of haematology 109 (6), 633-642, 2022	72	2022
The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation JE Aslan, SM Baker, CP Loren, KM Haley, A Itakura, J Pang, ... American Journal of Physiology-Cell Physiology 305 (5), C519-C528, 2013	64	2013
Death by committee: organellar trafficking and communication in apoptosis JE Aslan, G Thomas Traffic 10 (10), 1390-1404, 2009	64	2009
p21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophils A Itakura, JE Aslan, BT Kusanto, KG Phillips, JE Porter, PK Newton, X Nan, ... PloS one 8 (9), e73063, 2013	63	2013
Caught in the act–protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease G Thomas, JE Aslan, L Thomas, P Shinde, U Shinde, T Simmen Journal of Cell Science 130 (11), 1865-1876, 2017	59	2017
Analysis of Adverse Events and Intravenous Iron Infusion Formulations in Adults With and Without Prior Infusion Reactions AH Arastu, BK Elstrott, KL Martens, JL Cohen, MH Oakes, ZT Rub, ... JAMA Network Open 5 (3), e224488-e224488, 2022	52	2022
Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization RE Kosoff, JE Aslan, JC Kostyak, E Dulaimi, HY Chow, TY Prudnikova, ... Blood, The Journal of the American Society of Hematology 125 (19), 2995-3005, 2015	52	2015
P21 activated kinase signaling coordinates glycoprotein receptor VI–mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear JE Aslan, A Itakura, KM Haley, GW Tormoen, CP Loren, SM Baker, J Pang, ... Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1544-1551, 2013	52	2013
Histone deacetylase 6-mediated deacetylation of α-tubulin coordinates cytoskeletal and signaling events during platelet activation JE Aslan, KG Phillips, LD Healy, A Itakura, J Pang, OJT McCarty American Journal of Physiology-Cell Physiology 305 (12), C1230-C1239, 2013	49	2013
Platelet proteomes, pathways, and phenotypes as informants of vascular wellness and disease JE Aslan Arteriosclerosis, thrombosis, and vascular biology 41 (3), 999-1011, 2021	48	2021

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