| Design, synthesis, and evaluation of thiol-activated sources of sulfur dioxide (SO2) as antimycobacterial agents SR Malwal, D Sriram, P Yogeeswari, VB Konkimalla, H Chakrapani Journal of Medicinal Chemistry 55 (1), 553-557, 2012 | 159 | 2012 |
| A structural change in butyrophilin upon phosphoantigen binding underlies phosphoantigen-mediated Vγ9Vδ2 T cell activation Y Yang, L Li, L Yuan, X Zhou, J Duan, H Xiao, N Cai, S Han, X Ma, W Liu, ... Immunity 50 (4), 1043-1053. e5, 2019 | 117 | 2019 |
| Isoprenoid biosynthesis inhibitors targeting bacterial cell growth J Desai, Y Wang, K Wang, SR Malwal, E Oldfield ChemMedChem 11 (19), 2205-2215, 2016 | 45 | 2016 |
| Benzosulfones as photochemically activated sulfur dioxide (SO2) donors SR Malwal, H Chakrapani Organic & Biomolecular Chemistry 13 (8), 2399-2406, 2015 | 43 | 2015 |
| Benzosultines as sulfur dioxide (SO2) donors SR Malwal, M Gudem, A Hazra, H Chakrapani Organic Letters 15 (5), 1116-1119, 2013 | 43 | 2013 |
| Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA) MM Elsebaei, H Mohammad, M Abouf, NS Abutaleb, YA Hegazy, A Ghiaty, ... European journal of medicinal chemistry 148, 195-209, 2018 | 41 | 2018 |
| A highly selective sulfinate ester probe for thiol bioimaging SR Malwal, A Labade, AS Andhalkar, K Sengupta, H Chakrapani Chemical Communications 50 (78), 11533-11535, 2014 | 40 | 2014 |
| Synthesis and antimycobacterial activity of prodrugs of sulfur dioxide (SO2) SR Malwal, D Sriram, P Yogeeswari, H Chakrapani Bioorganic & medicinal chemistry letters 22 (11), 3603-3606, 2012 | 38 | 2012 |
| Thiol activated prodrugs of sulfur dioxide (SO2) as MRSA inhibitors KA Pardeshi, SR Malwal, A Banerjee, S Lahiri, R Rangarajan, ... Bioorganic & Medicinal Chemistry Letters 25 (13), 2694-2697, 2015 | 35 | 2015 |
| Bisphosphonate-generated ATP-analogs inhibit cell signaling pathways SR Malwal, B O’Dowd, X Feng, P Turhanen, C Shin, J Yao, BK Kim, ... Journal of the American Chemical Society 140 (24), 7568-7578, 2018 | 33 | 2018 |
| COVID-19 and other pandemics: How might they be prevented? E Oldfield, SR Malwal ACS Infectious Diseases 6 (7), 1563-1566, 2020 | 29 | 2020 |
| “Head‐to‐Middle” and “Head‐to‐Tail” cis‐Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase J Gao, TP Ko, L Chen, SR Malwal, J Zhang, X Hu, F Qu, W Liu, JW Huang, ... Angewandte Chemie 130 (3), 691-695, 2018 | 28 | 2018 |
| Farnesyl pyrophosphate synthase as a target for drug development: discovery of natural-product-derived inhibitors and their activity in pancreatic cancer cells S Han, X Li, Y Xia, Z Yu, N Cai, SR Malwal, X Han, E Oldfield, Y Zhang Journal of Medicinal Chemistry 62 (23), 10867-10896, 2019 | 25 | 2019 |
| Bacterial cell growth inhibitors targeting undecaprenyl diphosphate synthase and undecaprenyl diphosphate phosphatase Y Wang, J Desai, Y Zhang, SR Malwal, CJ Shin, X Feng, H Sun, G Liu, ... ChemMedChem 11 (20), 2311-2319, 2016 | 25 | 2016 |
| Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD+, NADPH, or NAD+/10‐Oxogeranial: Reaction Mechanisms Y Hu, W Liu, SR Malwal, Y Zheng, X Feng, TP Ko, CC Chen, Z Xu, M Liu, ... Angewandte Chemie International Edition 54 (51), 15478-15482, 2015 | 25 | 2015 |
| Moenomycin biosynthesis: structure and mechanism of action of the prenyltransferase MoeN5 L Zhang, CC Chen, TP Ko, JW Huang, Y Zheng, W Liu, I Wang, ... Angewandte Chemie International Edition 55 (15), 4716-4720, 2016 | 24 | 2016 |
| Catalytic role of conserved asparagine, glutamine, serine, and tyrosine residues in isoprenoid biosynthesis enzymes SR Malwal, J Gao, X Hu, Y Yang, W Liu, JW Huang, TP Ko, L Li, CC Chen, ... ACS catalysis 8 (5), 4299-4312, 2018 | 23 | 2018 |
| Discovery of lipophilic bisphosphonates that target bacterial cell wall and quinone biosynthesis SR Malwal, L Chen, H Hicks, F Qu, W Liu, A Shillo, WX Law, J Zhang, ... Journal of Medicinal Chemistry 62 (5), 2564-2581, 2019 | 19 | 2019 |
| Structure, in vivo detection and anti-bacterial activity of metabolites of SQ109, an anti-infective drug candidate SR Malwal, MD Zimmerman, N Alvarez, JP Sarathy, V Dartois, CA Nacy, ... ACS Infectious Diseases 7 (8), 2492-2507, 2021 | 14 | 2021 |
| Terpene cyclases and prenyltransferases: structures and mechanisms of action CC Chen, SR Malwal, X Han, W Liu, L Ma, C Zhai, L Dai, JW Huang, ... ACS catalysis 11 (1), 290-303, 2020 | 14 | 2020 |
