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Leonard Nelson
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Animal models of fulminant hepatic failure: a critical evaluation
PN Newsome, JN Plevris, LJ Nelson, PC Hayes
Liver Transplantation 6 (1), 21-31, 2000
1882000
Alcoholic liver disease: Utility of animal models
A Lamas-Paz, F Hao, LJ Nelson, MT Vázquez, S Canals, MG Del Moral, ...
World journal of gastroenterology 24 (45), 5063, 2018
1592018
Dissecting the molecular pathophysiology of drug-induced liver injury
H Ye, LJ Nelson, MG Del Moral, E Martínez-Naves, FJ Cubero
World journal of gastroenterology 24 (13), 1373, 2018
1492018
Which hepatocyte will it be? Hepatocyte choice for bioartificial liver support systems
J Tsiaoussis, PN Newsome, LJ Nelson, PC Hayes, JN Plevris
Liver Transplantation 7 (1), 2-10, 2001
1392001
Reclassifying hepatic cell death during liver damage: ferroptosis—a novel form of non-apoptotic cell death?
RU Macías-Rodríguez, ME Inzaugarat, A Ruiz-Margáin, LJ Nelson, ...
International journal of molecular sciences 21 (5), 1651, 2020
832020
Improvement of C3A cell metabolism for usage in bioartificial liver support systems
C Filippi, SA Keatch, D Rangar, LJ Nelson, PC Hayes, JN Plevris
Journal of hepatology 41 (4), 599-605, 2004
782004
Advanced preclinical models for evaluation of drug-induced liver injury–consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]
JC Fernandez-Checa, P Bagnaninchi, H Ye, P Sancho-Bru, ...
Journal of Hepatology 75 (4), 935-959, 2021
742021
Human hepatic Hepa RG cells maintain an organotypic phenotype with high intrinsic CYP 450 activity/metabolism and significantly outperform standard HepG2/C3A cells for …
LJ Nelson, K Morgan, P Treskes, K Samuel, CJ Henderson, C LeBled, ...
Basic & clinical pharmacology & toxicology 120 (1), 30-37, 2017
672017
Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery
Journal of British Surgery 107 (2), e161-e169, 2020
572020
Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model
LJ Nelson, M Navarro, P Treskes, K Samuel, O Tura-Ceide, SD Morley, ...
Scientific reports 5 (1), 17455, 2015
542015
Low-shear modelled microgravity environment maintains morphology and differentiated functionality of primary porcine hepatocyte cultures
LJ Nelson, SW Walker, PC Hayes, JN Plevris
Cells Tissues Organs 192 (2), 125-140, 2010
542010
Mitogen-activated protein kinases (MAPKs) and cholangiocarcinoma: the missing link
C Chen, LJ Nelson, MA Ávila, FJ Cubero
Cells 8 (10), 1172, 2019
522019
The simulated microgravity environment maintains key metabolic functions and promotes aggregation of primary porcine hepatocytes
KJ Dabos, LJ Nelson, TJ Bradnock, JA Parkinson, IH Sadler, PC Hayes, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1526 (2), 119-130, 2001
512001
Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver
W Gamal, P Treskes, K Samuel, GJ Sullivan, R Siller, V Srsen, K Morgan, ...
Scientific reports 7 (1), 37541, 2017
452017
Fibrotic events in the progression of cholestatic liver disease
H Wu, C Chen, S Ziani, LJ Nelson, MA Ávila, YA Nevzorova, FJ Cubero
Cells 10 (5), 1107, 2021
422021
Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure
PN Newsome, NC Henderson, LJ Nelson, C Dabos, C Filippi, C Bellamy, ...
BMC gastroenterology 10, 1-13, 2010
412010
Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures
M Arechederra, M Rullán, I Amat, D Oyon, L Zabalza, M Elizalde, ...
Gut 71 (6), 1141-1151, 2022
402022
The calcium‐binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid‐mediated injury
J Darragh, M Hunter, E Pohler, L Nelson, JF Dillon, R Nenutil, B Vojtesek, ...
The FEBS journal 273 (9), 1930-1947, 2006
392006
1H NMR spectroscopy as a tool to evaluate key metabolic functions of primary porcine hepatocytes after cryopreservation
KJ Dabos, JA Parkinson, C Hewage, LJ Nelson, IH Sadler, PC Hayes, ...
NMR in Biomedicine: An International Journal Devoted to the Development and …, 2002
372002
Dual targeting of G9a and DNA methyltransferase‐1 for the treatment of experimental cholangiocarcinoma
L Colyn, M Bárcena‐Varela, G Álvarez‐Sola, MU Latasa, I Uriarte, ...
Hepatology 73 (6), 2380-2396, 2021
352021
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