| Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells DM Foulkes, DP Byrne, W Yeung, S Shrestha, FP Bailey, S Ferries, ... Science signaling 11 (549), eaat7951, 2018 | 72 | 2018 |
| Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity PAE DOMINIC P. BYRNE, SAFAL SHRESTHA, MARTIN GALLER, MIN CAO, LEONARD A ... Science Signaling 13 (639), eaax2713, 2020 | 69 | 2020 |
| Cataloguing the dead: breathing new life into pseudokinase research S Shrestha, DP Byrne, JA Harris, N Kannan, PA Eyers The FEBS Journal 287 (19), 4150-4169, 2020 | 36 | 2020 |
| Nucleotide binding, evolutionary insights, and interaction partners of the pseudokinase Unc-51-like kinase 4 F Preuss, D Chatterjee, S Mathea, S Shrestha, J St-Germain, M Saha, ... Structure 28 (11), 1184-1196. e6, 2020 | 21 | 2020 |
| A chemical probe for dark kinase STK17B derives its potency and high selectivity through a unique P-loop conformation A Picado, A Chaikuad, CI Wells, S Shrestha, WJ Zuercher, JE Pickett, ... Journal of medicinal chemistry 63 (23), 14626-14646, 2020 | 17 | 2020 |
| A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily S Shrestha, S Katiyar, CE Sanz-Rodriguez, NR Kemppinen, HW Kim, ... Science signaling 13 (639), eaax6313, 2020 | 14 | 2020 |
| Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix MR Oliver, CR Horne, S Shrestha, JR Keown, LY Liang, SN Young, ... Nature Communications 12 (1), 1002, 2021 | 7 | 2021 |
| Computational tools and resources for pseudokinase research B O'Boyle, S Shrestha, K Kochut, PA Eyers, N Kannan Methods in enzymology 667, 403-426, 2022 | 4 | 2022 |
| Evolutionary and cellular analysis of the ‘dark’pseudokinase PSKH2 DP Byrne, S Shrestha, LA Daly, V Marensi, K Ramakrishnan, CE Eyers, ... Biochemical Journal 480 (2), 141-160, 2023 | 3 | 2023 |
| Protein kinase inhibitor selectivity “hinges” on evolution S Shrestha, G Bendzunas, N Kannan Structure 30 (12), 1561-1563, 2022 | 3 | 2022 |
| Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs MH Omar, DP Byrne, S Shrestha, TM Lakey, KS Lee, SM Lauer, ... Science Advances 10 (8), eadl1258, 2024 | | 2024 |
| Illuminating the functions of the understudied Fructosamine-3-kinase (FN3K) using a multi-omics approach reveals new links to lipid, carbon, and co-factor metabolic pathways N Kannan, S Shrestha, R Taujale, S Katiyar | | 2024 |
| Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms GN Bendzunas, DP Byrne, S Shrestha, LA Daly, SO Oswald, S Katiyar, ... bioRxiv, 2023.10. 05.561145, 2023 | | 2023 |
| Elucidating the Understudied Fructosamine-3-Kinase (FN3K) Family: A Combined Experimental and Computational Study on Structure, Function, Evolution, and Regulation S Shrestha University of Georgia, 2023 | | 2023 |
Natarajan KannanProfessor of Biochemistry and Bioinformatics, University of GeorgiaVerified email at uga.edu
