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Sadaf Amin
Sadaf Amin
Weill Cornell Medicine
Adresă de e-mail confirmată pe med.cornell.edu
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Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
M Crespo, E Vilar, SY Tsai, K Chang, S Amin, T Srinivasan, T Zhang, ...
Nature medicine 23 (7), 878-884, 2017
3422017
A modular platform for differentiation of human PSCs into all major ectodermal lineages
J Tchieu, B Zimmer, F Fattahi, S Amin, N Zeltner, S Chen, L Studer
Cell stem cell 21 (3), 399-410. e7, 2017
2022017
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding
T Maretzky, DR McIlwain, PDA Issuree, X Li, J Malapeira, S Amin, ...
Proceedings of the National Academy of Sciences 110 (28), 11433-11438, 2013
1812013
Genome editing in hPSCs reveals GATA6 haploinsufficiency and a genetic interaction with GATA4 in human pancreatic development
ZD Shi, K Lee, D Yang, S Amin, N Verma, QV Li, Z Zhu, CL Soh, R Kumar, ...
Cell stem cell 20 (5), 675-688. e6, 2017
1572017
ROCKII inhibition promotes the maturation of human pancreatic beta-like cells
Z Ghazizadeh, DI Kao, S Amin, B Cook, S Rao, T Zhou, T Zhang, Z Xiang, ...
Nature communications 8 (1), 298, 2017
862017
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience
JC Udeochu, S Amin, Y Huang, L Fan, ERS Torres, GK Carling, B Liu, ...
Nature neuroscience 26 (5), 737-750, 2023
552023
Discovery of a drug candidate for GLIS3-associated diabetes
S Amin, B Cook, T Zhou, Z Ghazizadeh, R Lis, T Zhang, M Khalaj, ...
Nature communications 9 (1), 2681, 2018
552018
Modeling cystic fibrosis using pluripotent stem cell-derived human pancreatic ductal epithelial cells
S Simsek, T Zhou, CL Robinson, SY Tsai, M Crespo, S Amin, X Lin, J Hon, ...
Stem cells translational medicine 5 (5), 572-579, 2016
542016
FOXC1 in human trabecular meshwork cells is involved in regulatory pathway that includes miR-204, MEIS2, and ITGβ1
SH Paylakhi, H Moazzeni, S Yazdani, P Rassouli, E Arefian, E Jaberi, ...
Experimental Eye Research 111, 112-121, 2013
542013
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival
T Zhou, TW Kim, CN Chong, L Tan, S Amin, Z Sadat Badieyan, ...
Nature Communications 9 (1), 4815, 2018
322018
A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity
SY Tsai, Z Ghazizadeh, HJ Wang, A Sadaf, FA Ortega, ZS Badieyan, ...
Cardiovascular research, 2019
202019
Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy
H Majd, S Amin, Z Ghazizadeh, A Cesiulis, E Arroyo, K Lankford, A Majd, ...
Cell Stem Cell 30 (5), 632-647. e10, 2023
162023
New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia
S Amin, G Carling, L Gan
Current Opinion in Neurobiology 72, 131-139, 2022
162022
MicroRNAs that target RGS5
A Banaei-Esfahani, H Moazzeni, PN Nosar, S Amin, E Arefian, ...
Iranian journal of basic medical sciences 18 (2), 108, 2015
122015
Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders
Y Huang, B Liu, SC Sinha, S Amin, L Gan
Molecular Neurodegeneration 18 (1), 79, 2023
42023
Autophagy prevents microglial senescence
S Amin, B Liu, L Gan
Nature Cell Biology 25, 923–925, 2023
42023
A dual SHOX2: GFP; MYH6: mCherry knockin hESC reporter line for derivation of human SAN-like cells
Z Ghazizadeh, J Zhu, F Fattahi, A Tang, X Sun, S Amin, SY Tsai, M Khalaj, ...
Iscience 25 (4), 2022
32022
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
GK Carling, L Fan, NR Foxe, K Norman, P Ye, MY Wong, D Zhu, F Yu, ...
bioRxiv, 2024.01. 24.577107, 2024
2024
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity
H Chen, L Fan, Q Guo, MY Wong, F Yu, N Foxe, W Wang, A Nessim, ...
Research Square, 2023
2023
A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells
L Tan, X Duan, P Mutyala, T Zhou, S Amin, T Zhang, B Herbst, G Askan, ...
Journal of Molecular Cell Biology 15 (6), mjad039, 2023
2023
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