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Gary Litherland
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Protein kinase B (PKB/Akt)–a key regulator of glucose transport?
E Hajduch, GJ Litherland, HS Hundal
FEBS letters 492 (3), 199-203, 2001
3882001
Cellular senescence in osteoarthritis pathology
K McCulloch, GJ Litherland, TS Rai
Aging cell 16 (2), 210-218, 2017
3062017
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
E Hajduch, A Balendran, IH Batty, GJ Litherland, AS Blair, CP Downes, ...
Diabetologia 44, 173-183, 2001
2882001
Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases
W Hui, GJ Litherland, MS Elias, GI Kitson, TE Cawston, AD Rowan, ...
Annals of the rheumatic diseases 71 (3), 455-462, 2012
2562012
Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress: evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated …
AS Blair, E Hajduch, GJ Litherland, HS Hundal
Journal of Biological Chemistry 274 (51), 36293-36299, 1999
2061999
Key role for ceramides in mediating insulin resistance in human muscle cells
L Pickersgill, GJ Litherland, AS Greenberg, M Walker, SJ Yeaman
Journal of Biological Chemistry 282 (17), 12583-12589, 2007
1952007
Differential Toll-like receptor-dependent collagenase expression in chondrocytes
Q Zhang, W Hui, GJ Litherland, MJ Barter, R Davidson, C Darrah, ...
Annals of the rheumatic diseases 67 (11), 1633-1641, 2008
1132008
Subcellular localization and adaptive up-regulation of the System A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes
R HYDE, GR CHRISTIE, GJ LITHERLAND, E HAJDUCH, PM TAYLOR, ...
Biochemical Journal 355 (3), 563-568, 2001
992001
HDAC-mediated control of ERK-and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes
MJ Barter, L Pybus, GJ Litherland, AD Rowan, IM Clark, DR Edwards, ...
Matrix Biology 29 (7), 602-612, 2010
962010
Metalloproteases as potential therapeutic targets in arthritis treatment
AD Rowan, GJ Litherland, W Hui, JM Milner
Expert opinion on therapeutic targets 12 (1), 1-18, 2008
842008
Fructose transport and metabolism in adipose tissue of Zucker rats: diminished GLUT5 activity during obesity and insulin resistance
GJ Litherland, E Hajduch, GW Gould, HS Hundal
Molecular and cellular biochemistry 261, 23-33, 2004
772004
A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B
K Peyrollier, E Hajduch, A Gray, GJ Litherland, AR Prescott, NR Leslie, ...
Biochemical Journal 352 (3), 617-622, 2000
732000
Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signaling-dependent
GJ Litherland, C Dixon, RL Lakey, T Robson, D Jones, DA Young, ...
Journal of biological chemistry 283 (21), 14221-14229, 2008
672008
Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family
H Xie, SG Patching, MP Gallagher, GJ Litherland, AR Brough, H Venter, ...
Molecular membrane biology 21 (5), 323-336, 2004
662004
Intracellular signalling mechanisms regulating glucose transport in insulin-sensitive tissues
GJ Litherland, E Hajduch, HS Hundal
Molecular membrane biology 18 (3), 195-204, 2001
632001
Exosomes in intercellular communication and implications for osteoarthritis
S Asghar, GJ Litherland, JC Lockhart, CS Goodyear, A Crilly
Rheumatology 59 (1), 57-68, 2020
612020
Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibition of the P38 mitogen-activated protein kinase pathway
W Hui, GJ Litherland, M Jefferson, MJ Barter, MS Elias, TE Cawston, ...
Rheumatology 49 (11), 2043-2053, 2010
602010
Protein kinase C isoforms ζ and ι mediate collagenase expression and cartilage destruction via STAT3-and ERK-dependent c-fos induction
GJ Litherland, MS Elias, W Hui, CD Macdonald, JB Catterall, MJ Barter, ...
Journal of biological chemistry 285 (29), 22414-22425, 2010
562010
Cytokine-induced MMP13 expression in human chondrocytes is dependent on activating transcription factor 3 (ATF3) regulation
CM Chan, CD Macdonald, GJ Litherland, DJ Wilkinson, A Skelton, ...
Journal of Biological Chemistry 292 (5), 1625-1636, 2017
532017
The serpin superfamily and their role in the regulation and dysfunction of serine protease activity in COPD and other chronic lung diseases
GA Kelly-Robinson, JA Reihill, FT Lundy, LP McGarvey, JC Lockhart, ...
International journal of molecular sciences 22 (12), 6351, 2021
462021
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