| In vivo–directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous D Dalkara, LC Byrne, RR Klimczak, M Visel, L Yin, WH Merigan, ... Science translational medicine 5 (189), 189ra76-189ra76, 2013 | 685 | 2013 |
| Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis N Aït-Ali, R Fridlich, G Millet-Puel, E Clérin, F Delalande, C Jaillard, ... Cell 161 (4), 817-832, 2015 | 350 | 2015 |
| Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous D Dalkara, KD Kolstad, N Caporale, M Visel, RR Klimczak, DV Schaffer, ... Molecular Therapy 17 (12), 2096-2102, 2009 | 340 | 2009 |
| Partial recovery of visual function in a blind patient after optogenetic therapy JA Sahel, E Boulanger-Scemama, C Pagot, A Arleo, F Galluppi, JN Martel, ... Nature medicine 27 (7), 1223-1229, 2021 | 269 | 2021 |
| A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells RR Klimczak, JT Koerber, D Dalkara, JG Flannery, DV Schaffer PloS one 4 (10), e7467, 2009 | 219 | 2009 |
| Intravitreal injection of AAV2 transduces macaque inner retina L Yin, K Greenberg, JJ Hunter, D Dalkara, KD Kolstad, BD Masella, ... Investigative ophthalmology & visual science 52 (5), 2775-2783, 2011 | 203 | 2011 |
| Emerging therapies for inherited retinal degeneration HPN Scholl, RW Strauss, MS Singh, D Dalkara, B Roska, S Picaud, ... Science translational medicine 8 (368), 368rv6-368rv6, 2016 | 200 | 2016 |
| Molecular evolution of adeno-associated virus for enhanced glial gene delivery JT Koerber, R Klimczak, JH Jang, D Dalkara, JG Flannery, DV Schaffer Molecular Therapy 17 (12), 2088-2095, 2009 | 199 | 2009 |
| LiGluR restores visual responses in rodent models of inherited blindness N Caporale, KD Kolstad, T Lee, I Tochitsky, D Dalkara, D Trauner, ... Molecular therapy 19 (7), 1212-1219, 2011 | 196 | 2011 |
| Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV restores ON and OFF visual responses in blind mice E Macé, R Caplette, O Marre, A Sengupta, A Chaffiol, P Barbe, ... Molecular Therapy 23 (1), 7-16, 2015 | 191 | 2015 |
| Rapid optical control of nociception with an ion-channel photoswitch A Mourot, T Fehrentz, Y Le Feuvre, CM Smith, C Herold, D Dalkara, ... Nature methods 9 (4), 396-402, 2012 | 183 | 2012 |
| Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration LC Byrne, D Dalkara, G Luna, SK Fisher, E Clérin, JA Sahel, T Léveillard, ... The Journal of clinical investigation 125 (1), 105-116, 2015 | 168 | 2015 |
| Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina A Sengupta, A Chaffiol, E Macé, R Caplette, M Desrosiers, M Lampič, ... EMBO molecular medicine 8 (11), 1248-1264, 2016 | 166 | 2016 |
| Let there be light: gene and cell therapy for blindness D Dalkara, O Goureau, K Marazova, JA Sahel Human gene therapy 27 (2), 134-147, 2016 | 143 | 2016 |
| Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve V Pernet, S Joly, D Dalkara, N Jordi, O Schwarz, F Christ, DV Schaffer, ... Neurobiology of disease 51, 202-213, 2013 | 125 | 2013 |
| AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa D Dalkara, KD Kolstad, KI Guerin, NV Hoffmann, M Visel, RR Klimczak, ... Molecular Therapy 19 (9), 1602-1608, 2011 | 125 | 2011 |
| Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve V Pernet, S Joly, N Jordi, D Dalkara, A Guzik-Kornacka, JG Flannery, ... Cell death & disease 4 (7), e734-e734, 2013 | 124 | 2013 |
| A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina A Chaffiol, R Caplette, C Jaillard, E Brazhnikova, M Desrosiers, E Dubus, ... Molecular Therapy 25 (11), 2546-2560, 2017 | 121 | 2017 |
| Vertebrate cone opsins enable sustained and highly sensitive rapid control of Gi/o signaling in anxiety circuitry OA Masseck, K Spoida, D Dalkara, T Maejima, JM Rubelowski, ... Neuron 81 (6), 1263-1273, 2014 | 104 | 2014 |
| Noninvasive gene delivery to foveal cones for vision restoration H Khabou, M Garita-Hernandez, A Chaffiol, S Reichman, C Jaillard, ... JCI insight 3 (2), 2018 | 102 | 2018 |
Jose Alain SahelSorbonne Université/ University of Pittsburgh School of MedicineVerified email at inserm.fr
