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Xu Zhiwen
Xu Zhiwen
Verified email at ust.hk
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Year
Human tRNA synthetase catalytic nulls with diverse functions
WS Lo, E Gardiner, Z Xu, CF Lau, F Wang, JJ Zhou, JD Mendlein, ...
Science 345 (6194), 328-332, 2014
1292014
Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities
J Zhou, CF Lau, XU Zhiwen, WS Lo, KH Piehl, LA Greene
US Patent 8,404,242, 2013
992013
GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone
L Ren, F Wang, Z Xu, WM Chan, C Zhao, H Xue
Biochemical pharmacology 79 (9), 1337-1344, 2010
942010
GABAA receptor subtype selectivity underlying selective anxiolytic effect of baicalin
F Wang, Z Xu, L Ren, SY Tsang, H Xue
Neuropharmacology 55 (7), 1231-1237, 2008
842008
Compositions and methods comprising histidyl-TRNA synthetase splice variants having non-canonical biological activities
J Zhou, CF Lau, XU Zhiwen, WS Lo, KH Piehl, LA Greene
US Patent 8,753,638, 2014
742014
Two isoforms of GABAA receptor β2 subunit with different electrophysiological properties: differential expression and genotypical correlations in schizophrenia
C Zhao, Z Xu, J Chen, Z Yu, KL Tong, WS Lo, FW Pun, SK Ng, SY Tsang, ...
Molecular psychiatry 11 (12), 1092-1105, 2006
682006
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases
LA Greene, KP Chiang, F Hong, AP Vasserot, JD Watkins, CL Quinn, ...
US Patent 8,945,541, 2015
662015
Structures of human histidyl-trna synthetase and methods of use
XU Zhiwen, Z Wei, XL Yang, M Zhang, P Schimmel
US Patent App. 13/948,982, 2014
642014
The Evolution of GABAA Receptor–Like Genes
SY Tsang, SK Ng, Z Xu, H Xue
Molecular biology and evolution 24 (2), 599-610, 2007
642007
Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis
JJ Zhou, F Wang, Z Xu, WS Lo, CF Lau, KP Chiang, LA Nangle, ...
Journal of Biological Chemistry 289 (28), 19269-19275, 2014
592014
Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing
Z Xu, Z Wei, JJ Zhou, F Ye, WS Lo, F Wang, CF Lau, J Wu, LA Nangle, ...
Structure 20 (9), 1470-1477, 2012
562012
Anxiolytic-like effect of baicalin and its additivity with other anxiolytics
Z Xu, F Wang, SY Tsang, KH Ho, H Zheng, CT Yuen, CY Chow, H Xue
Planta medica 72 (02), 189-192, 2006
542006
Positive Selection within the Schizophrenia-Associated GABAA Receptor β2 Gene
WS Lo, Z Xu, Z Yu, FW Pun, SK Ng, J Chen, KL Tong, C Zhao, X Xu, ...
PLoS One 2 (5), e462, 2007
512007
Alternative-Splicing in the Exon-10 Region of GABAA Receptor β2 Subunit Gene: Relationships between Novel Isoforms and Psychotic Disorders
C Zhao, Z Xu, F Wang, J Chen, SK Ng, PW Wong, Z Yu, FW Pun, L Ren, ...
PloS one 4 (9), e6977, 2009
472009
Bi-allelic mutations in Phe-tRNA synthetase associated with a multi-system pulmonary disease support non-translational function
Z Xu, WS Lo, DB Beck, LA Schuch, M Oláhová, R Kopajtich, YE Chong, ...
The American Journal of Human Genetics 103 (1), 100-114, 2018
422018
Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy
J Friedman, DE Smith, MY Issa, V Stanley, R Wang, MI Mendes, ...
Nature communications 10 (1), 707, 2019
382019
Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses
RA Adams, C Fernandes-Cerqueira, A Notarnicola, E Mertsching, Z Xu, ...
Cellular & molecular immunology 18 (6), 1463-1475, 2021
362021
Structural basis for homeodomain recognition by the cell-cycle regulator Geminin
B Zhou, C Liu, Z Xu, G Zhu
Proceedings of the National Academy of Sciences 109 (23), 8931-8936, 2012
322012
6, 2′-Dihydroxyflavone, a subtype-selective partial inverse agonist of GABAA receptor benzodiazepine site
F Wang, Z Xu, CT Yuen, CY Chow, YL Lui, SY Tsang, H Xue
Neuropharmacology 53 (4), 574-582, 2007
302007
A recombination hotspot in a schizophrenia-associated region of GABRB2
SK Ng, WS Lo, FW Pun, C Zhao, Z Yu, J Chen, KL Tong, Z Xu, SY Tsang, ...
PloS one 5 (3), e9547, 2010
292010
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