How curved membranes recruit amphipathic helices and protein anchoring motifs NS Hatzakis, VK Bhatia, J Larsen, KL Madsen, PY Bolinger, AH Kunding, ... Nature chemical biology 5 (11), 835-841, 2009 | 484 | 2009 |
Amphipathic motifs in BAR domains are essential for membrane curvature sensing VK Bhatia, KL Madsen, PY Bolinger, A Kunding, P Hedegård, U Gether, ... The EMBO journal 28 (21), 3303-3314, 2009 | 303 | 2009 |
Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD TS Thorsen, KL Madsen, N Rebola, M Rathje, V Anggono, A Bach, ... Proceedings of the National Academy of Sciences 107 (1), 413-418, 2010 | 140 | 2010 |
BAR domains, amphipathic helices and membrane-anchored proteins use the same mechanism to sense membrane curvature KL Madsen, VK Bhatia, U Gether, D Stamou FEBS letters 584 (9), 1848-1855, 2010 | 124 | 2010 |
GABAA receptor function is regulated by lipid bilayer elasticity R Søgaard, TM Werge, C Bertelsen, C Lundbye, KL Madsen, CH Nielsen, ... Biochemistry 45 (43), 13118-13129, 2006 | 119 | 2006 |
Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions C Bjerggaard, JU Fog, H Hastrup, K Madsen, CJ Loland, JA Javitch, ... Journal of Neuroscience 24 (31), 7024-7036, 2004 | 115 | 2004 |
Molecular determinants for the complex binding specificity of the PDZ domain in PICK1 KL Madsen, T Beuming, MY Niv, C Chang, KK Dev, H Weinstein, ... Journal of Biological Chemistry 280 (21), 20539-20548, 2005 | 108 | 2005 |
PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance B Holst, KL Madsen, AM Jansen, C Jin, M Rickhag, VK Lund, M Jensen, ... PLoS biology 11 (4), e1001542, 2013 | 89 | 2013 |
AMPA receptor pHluorin-GluA2 reports NMDA receptor-induced intracellular acidification in hippocampal neurons M Rathje, H Fang, JL Bachman, V Anggono, U Gether, RL Huganir, ... Proceedings of the National Academy of Sciences 110 (35), 14426-14431, 2013 | 74 | 2013 |
Membrane localization is critical for activation of the PICK1 BAR domain KL Madsen, J Eriksen, L Milan‐Lobo, DS Han, MY Niv, ... Traffic 9 (8), 1327-1343, 2008 | 56 | 2008 |
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1 M Bassan, H Liu, KL Madsen, W Armsen, J Zhou, T DeSilva, W Chen, ... European Journal of Neuroscience 27 (1), 66-82, 2008 | 54 | 2008 |
Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes VK Lund, KL Madsen, O Kjaerulff Autophagy 14 (9), 1520-1542, 2018 | 52 | 2018 |
A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter M Rickhag, FH Hansen, G Sørensen, KN Strandfelt, B Andresen, ... Nature communications 4 (1), 1580, 2013 | 52 | 2013 |
Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway KL Madsen, TS Thorsen, T Rahbek-Clemmensen, J Eriksen, U Gether Journal of Biological Chemistry 287 (15), 12293-12308, 2012 | 50 | 2012 |
Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands S Erlendsson, M Rathje, PO Heidarsson, FM Poulsen, KL Madsen, ... Journal of Biological Chemistry 289 (36), 25327-25340, 2014 | 48 | 2014 |
An amphipathic helix directs cellular membrane curvature sensing and function of the BAR domain protein PICK1 R Herlo, VK Lund, MD Lycas, AM Jansen, G Khelashvili, RC Andersen, ... Cell reports 23 (7), 2056-2069, 2018 | 45 | 2018 |
Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1 A Bach, N Stuhr-Hansen, TS Thorsen, N Bork, IS Moreira, K Frydenvang, ... Organic & biomolecular chemistry 8 (19), 4281-4288, 2010 | 44 | 2010 |
Early stage alpha-synuclein amyloid fibrils are reservoirs of membrane-binding species T Skamris, C Marasini, KL Madsen, V Foderà, B Vestergaard Scientific reports 9 (1), 1733, 2019 | 42 | 2019 |
Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-ray scattering ML Karlsen, TS Thorsen, N Johner, I Ammendrup-Johnsen, S Erlendsson, ... Structure 23 (7), 1258-1270, 2015 | 42 | 2015 |
Elucidating the molecular basis for inhibitory neurotransmission regulation by artemisinins VB Kasaragod, TJ Hausrat, N Schaefer, M Kuhn, NR Christensen, ... Neuron 101 (4), 673-689. e11, 2019 | 41 | 2019 |