BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL G Greaves, M Milani, M Butterworth, RJ Carter, DP Byrne, PA Eyers, ... Cell Death & Differentiation 26 (6), 1037-1047, 2019 | 69 | 2019 |
Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and-independent manner S Varadarajan, P Poornima, M Milani, K Gowda, S Amin, HG Wang, ... Oncotarget 6 (14), 12668, 2015 | 59 | 2015 |
DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis M Milani, DP Byrne, G Greaves, M Butterworth, GM Cohen, PA Eyers, ... Cell death & disease 8 (1), e2552-e2552, 2018 | 44 | 2018 |
High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia CM Lucas, M Milani, M Butterworth, N Carmell, LJ Scott, RE Clark, ... Leukemia 30 (6), 1273-1281, 2016 | 34 | 2016 |
DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis M Milani, AJ Beckett, A Al-Zebeeby, X Luo, IA Prior, GM Cohen, ... Cell death discovery 5 (1), 117, 2019 | 27 | 2019 |
Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck RJ Carter, M Milani, M Butterworth, A Alotibi, N Harper, G Yedida, ... Cell Death & Disease 10 (12), 912, 2019 | 26 | 2019 |
Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies A Al-Zebeeby, M Vogler, M Milani, C Richards, A Alotibi, G Greaves, ... Haematologica 104 (5), 1016, 2019 | 20 | 2019 |
Karyotypic data detect interpopulational variation in Physalaemus olfersii and the first case of a supernumerary chromosome in the genus M Milani, CS Cassini, SM Recco-Pimentel, LB Lourenço Animal Biology Journal 2, 21-28, 2010 | 19 | 2010 |
Plasma Hsp90 level as a marker of early acute lymphoblastic leukemia engraftment and progression in mice M Milani, ABA Laranjeira, JF de Vasconcellos, SR Brandalise, AE Nowill, ... PLoS One 10 (6), e0129298, 2015 | 13 | 2015 |
Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis G Yedida, M Milani, GM Cohen, S Varadarajan Cell Death & Disease 10 (7), 521, 2019 | 12 | 2019 |
Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis RJ Carter, M Milani, AJ Beckett, S Liu, IA Prior, GM Cohen, S Varadarajan Cell Death & Disease 13 (5), 436, 2022 | 11 | 2022 |
Proteomic analysis of Huntington’s disease medium spiny neurons identifies alterations in lipid droplets KT Tshilenge, CG Aguirre, J Bons, AA Gerencser, N Basisty, S Song, ... Molecular & Cellular Proteomics 22 (5), 2023 | 7 | 2023 |
Calcium signaling in lysosome-dependent cell death M Milani, P Pihán, C Hetz Cell Calcium 113, 102751, 2023 | 5 | 2023 |
Proapoptotic RECS1: a requisite gateway to lysosomal dysfunction and death P Pihán, M Milani, C Hetz Neural Regeneration Research 17 (12), 2695-2696, 2022 | 3 | 2022 |
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis Y Hazari, H Urra, VAG Lopez, J Diaz, G Tamburini, M Milani, P Pihan, ... bioRxiv, 2023.05. 02.538835, 2023 | 2 | 2023 |
PO-061 BCL-2 family of proteins, BCL-XL and MCL-1, regulate apoptosis and cancer cell survival by different mechanisms G Greaves, M Milani, D Byrne, R Carter, M Butterworth, X Luo, P Eyers, ... ESMO Open 3, A44-A45, 2018 | 2 | 2018 |
ER shaping proteins regulate mitochondrial fission, outer membrane permeabilization and apoptosis M Milani, GM Cohen, S Varadarajan bioRxiv, 340448, 2018 | 2 | 2018 |
Mitochondria-associated niches in health and disease M Milani, P Pihán, C Hetz Journal of Cell Science 135 (23), jcs259634, 2022 | 1 | 2022 |
BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress C Sepulveda, M Milani, V Morales, G Tamburini, N Montes, C Hetz bioRxiv, 2024.03. 26.586784, 2024 | | 2024 |
促凋亡 RECS1: 溶酶体功能障碍和死亡的必要途径 P Pihán, M Milani, C Hetz 中国神经再生研究 (英文版) 17 (12), 2695, 2022 | | 2022 |