| Bacterial glycoproteins: functions, biosynthesis and applications RK Upreti, M Kumar, V Shankar Proteomics 3 (4), 363-379, 2003 | 221 | 2003 |
| Evaluation and critical assessment of putative MCL-1 inhibitors S Varadarajan, M Vogler, M Butterworth, D Dinsdale, LD Walensky, ... Cell Death & Differentiation 20 (11), 1475-1484, 2013 | 115 | 2013 |
| BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL G Greaves, M Milani, M Butterworth, RJ Carter, DP Byrne, PA Eyers, ... Cell Death & Differentiation 26 (6), 1037-1047, 2019 | 69 | 2019 |
| A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum S Varadarajan, ETW Bampton, JL Smalley, K Tanaka, RE Caves, ... Cell Death & Differentiation, 2012 | 67 | 2012 |
| Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis S Varadarajan, M Butterworth, J Wei, M Pellecchia, D Dinsdale, ... Neoplasia 15 (5), 568-IN22, 2013 | 61 | 2013 |
| Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and-independent manner S Varadarajan, P Poornima, M Milani, K Gowda, S Amin, HG Wang, ... Oncotarget 6 (14), 12668, 2015 | 59 | 2015 |
| Drosophila Omi, a mitochondrial‐localized IAP antagonist and proapoptotic serine protease M Challa, S Malladi, BJ Pellock, D Dresnek, S Varadarajan, YW Yin, ... The EMBO journal 26 (13), 3144-3156, 2007 | 58 | 2007 |
| TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1 JK Son, S Varadarajan, SB Bratton Cell Death & Differentiation 17 (8), 1288-1301, 2010 | 54 | 2010 |
| DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis M Milani, DP Byrne, G Greaves, M Butterworth, GM Cohen, PA Eyers, ... Cell death & disease 8 (1), e2552-e2552, 2018 | 44 | 2018 |
| BH3 profiling and a toolkit of BH3-mimetic drugs predict anti-apoptotic dependence of cancer cells M Butterworth, A Pettitt, S Varadarajan, GM Cohen British journal of cancer 114 (6), 638-641, 2016 | 44 | 2016 |
| High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia CM Lucas, M Milani, M Butterworth, N Carmell, LJ Scott, RE Clark, ... Leukemia 30 (6), 1273-1281, 2016 | 34 | 2016 |
| Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis S Varadarajan, K Tanaka, JL Smalley, ETW Bampton, M Pellecchia, ... PLoS One 8 (2), e56603, 2013 | 32 | 2013 |
| DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis M Milani, AJ Beckett, A Al-Zebeeby, X Luo, IA Prior, GM Cohen, ... Cell death discovery 5 (1), 117, 2019 | 27 | 2019 |
| Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck RJ Carter, M Milani, M Butterworth, A Alotibi, N Harper, G Yedida, ... Cell Death & Disease 10 (12), 912, 2019 | 26 | 2019 |
| Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies A Al-Zebeeby, M Vogler, M Milani, C Richards, A Alotibi, G Greaves, ... Haematologica 104 (5), 1016, 2019 | 20 | 2019 |
| The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegeneration S Varadarajan, C Breda, JL Smalley, M Butterworth, SN Farrow, F Giorgini, ... Cell Death & Differentiation 22 (8), 1388-1396, 2015 | 20 | 2015 |
| Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations K Henz, A Al-Zebeeby, M Basoglu, S Fulda, GM Cohen, S Varadarajan, ... Biological Chemistry 400 (2), 181-185, 2019 | 13 | 2019 |
| Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis G Yedida, M Milani, GM Cohen, S Varadarajan Cell Death & Disease 10 (7), 521, 2019 | 12 | 2019 |
| Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis RJ Carter, M Milani, AJ Beckett, S Liu, IA Prior, GM Cohen, S Varadarajan Cell Death & Disease 13 (5), 436, 2022 | 11 | 2022 |
| Stinging viral tumors: what we know from head and neck cancers E Saulters, JF Woolley, S Varadarajan, TM Jones, LN Dahal Cancer Research 81 (15), 3945-3952, 2021 | 10 | 2021 |
