IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells C Schinke, O Giricz, W Li, A Shastri, S Gordon, L Barreyro, T Bhagat, ... Blood, The Journal of the American Society of Hematology 125 (20), 3144-3152, 2015 | 179 | 2015 |
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ... Elife 8, e50663, 2019 | 116 | 2019 |
Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture J Han, H Chang, O Giricz, GY Lee, FL Baehner, JW Gray, MJ Bissell, ... PLoS computational biology 6 (2), e1000684, 2010 | 116 | 2010 |
Hsa‐miR‐375 is differentially expressed during breast lobular neoplasia and promotes loss of mammary acinar polarity O Giricz, PA Reynolds, A Ramnauth, C Liu, T Wang, L Stead, G Childs, ... The Journal of pathology 226 (1), 108-119, 2012 | 91 | 2012 |
Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells A Shastri, G Choudhary, M Teixeira, S Gordon-Mitchell, N Ramachandra, ... The Journal of clinical investigation 128 (12), 5479-5488, 2018 | 77 | 2018 |
Kidney cancer is characterized by aberrant methylation of tissue-specific enhancers that are prognostic for overall survival CY Hu, D Mohtat, Y Yu, YA Ko, N Shenoy, S Bhattacharya, MC Izquierdo, ... Clinical Cancer Research 20 (16), 4349-4360, 2014 | 74 | 2014 |
North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies UA Shah, EY Chung, O Giricz, K Pradhan, K Kataoka, S Gordon-Mitchell, ... Blood, The Journal of the American Society of Hematology 132 (14), 1507-1518, 2018 | 73 | 2018 |
Epigenetically aberrant stroma in MDS propagates disease via Wnt/β-catenin activation TD Bhagat, S Chen, M Bartenstein, AT Barlowe, D Von Ahrens, ... Cancer research 77 (18), 4846-4857, 2017 | 70 | 2017 |
GRB7 is required for triple-negative breast cancer cell invasion and survival O Giricz, V Calvo, SC Pero, DN Krag, JA Sparano, PA Kenny Breast cancer research and treatment 133, 607-615, 2012 | 62 | 2012 |
Inhibitors of BRAF dimers using an allosteric site XM Cotto-Rios, B Agianian, N Gitego, E Zacharioudakis, O Giricz, Y Wu, ... Nature communications 11 (1), 4370, 2020 | 61 | 2020 |
Notch pathway is activated via genetic and epigenetic alterations and is a therapeutic target in clear cell renal cancer TD Bhagat, Y Zou, S Huang, J Park, MB Palmer, C Hu, W Li, N Shenoy, ... Journal of Biological Chemistry 292 (3), 837-846, 2017 | 57 | 2017 |
TACE‐dependent TGFα shedding drives triple‐negative breast cancer cell invasion O Giricz, V Calvo, EA Peterson, CM Abouzeid, PA Kenny International journal of cancer 133 (11), 2587-2595, 2013 | 53 | 2013 |
Multiple myeloma and its precursor disease among firefighters exposed to the World Trade Center disaster O Landgren, R Zeig-Owens, O Giricz, D Goldfarb, K Murata, K Thoren, ... JAMA oncology 4 (6), 821-827, 2018 | 51 | 2018 |
High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis Y Yu, Y Mo, D Ebenezer, S Bhattacharyya, H Liu, S Sundaravel, O Giricz, ... Journal of Biological Chemistry 288 (13), 8805-8814, 2013 | 50 | 2013 |
Pexmetinib: a novel dual inhibitor of Tie2 and p38 MAPK with efficacy in preclinical models of myelodysplastic syndromes and acute myeloid leukemia L Bachegowda, K Morrone, SL Winski, I Mantzaris, M Bartenstein, ... Cancer research 76 (16), 4841-4849, 2016 | 42 | 2016 |
Bisected, complex N-glycans and galectins in mouse mammary tumor progression and human breast cancer HE Miwa, WR Koba, EJ Fine, O Giricz, PA Kenny, P Stanley Glycobiology 23 (12), 1477-1490, 2013 | 42 | 2013 |
ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine NE Rahmani, N Ramachandra, S Sahu, N Gitego, A Lopez, K Pradhan, ... Blood cancer journal 11 (9), 157, 2021 | 40 | 2021 |
The normalization of gene expression data in melanoma: investigating the use of glyceraldehyde 3-phosphate dehydrogenase and 18S ribosomal RNA as internal reference genes for … O Giricz, JL Lauer-Fields, GB Fields Analytical biochemistry 380 (1), 137-139, 2008 | 37 | 2008 |
The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma O Giricz, Y Mo, KB Dahlman, XM Cotto-Rios, C Vardabasso, H Nguyen, ... JCI insight 3 (14), 2018 | 36 | 2018 |
Targeting chemokine pathways in esophageal adenocarcinoma MS Shrivastava, Z Hussain, O Giricz, N Shenoy, R Polineni, A Maitra, ... Cell cycle 13 (21), 3320-3327, 2014 | 36 | 2014 |