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John Whitelock
John Whitelock
Adresă de e-mail confirmată pe unsw.edu.au
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The Degradation of Human Endothelial Cell-derived Perlecan and Release of Bound Basic Fibroblast Growth Factor by Stromelysin, Collagenase, Plasmin, and Heparanases (∗)
JM Whitelock, AD Murdoch, RV Iozzo, PA Underwood
Journal of Biological Chemistry 271 (17), 10079-10086, 1996
7891996
Heparan sulfate: a complex polymer charged with biological activity
JM Whitelock, RV Iozzo
Chemical reviews 105 (7), 2745-2764, 2005
5192005
Diverse cell signaling events modulated by perlecan
JM Whitelock, J Melrose, RV Iozzo
Biochemistry 47 (43), 11174-11183, 2008
3122008
Oxidative damage to extracellular matrix and its role in human pathologies
MD Rees, EC Kennett, JM Whitelock, MJ Davies
Free Radical Biology and Medicine 44 (12), 1973-2001, 2008
2782008
Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo.
B Sharma, M Handler, I Eichstetter, JM Whitelock, MA Nugent, RV Iozzo
The Journal of clinical investigation 102 (8), 1599-1608, 1998
2491998
Perlecan: how does one molecule do so many things?
SM Knox, JM Whitelock
Cellular and Molecular Life Sciences CMLS 63, 2435-2445, 2006
2042006
Not all perlecans are created equal: interactions with fibroblast growth factor (FGF) 2 and FGF receptors
S Knox, C Merry, S Stringer, J Melrose, J Whitelock
Journal of Biological Chemistry 277 (17), 14657-14665, 2002
1972002
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ...
Nature communications 10 (1), 3637, 2019
1942019
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis
VN Patel, SM Knox, KM Likar, CA Lathrop, R Hossain, S Eftekhari, ...
Oxford University Press for The Company of Biologists Limited 134 (23), 4177 …, 2007
1892007
The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7
M Mongiat, K Taylor, J Otto, S Aho, J Uitto, JM Whitelock, RV Iozzo
Journal of Biological Chemistry 275 (10), 7095-7100, 2000
1852000
Comparative spatial and temporal localisation of perlecan, aggrecan and type I, II and IV collagen in the ovine meniscus: an ageing study
J Melrose, S Smith, M Cake, R Read, J Whitelock
Histochemistry and cell biology 124, 225-235, 2005
1592005
Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells
JM Whitelock, LD Graham, J Melrose, AD Murdoch, RV Iozzo, ...
Matrix biology 18 (2), 163-178, 1999
1591999
The modulation of platelet adhesion and activation by chitosan through plasma and extracellular matrix proteins
MS Lord, B Cheng, SJ McCarthy, MS Jung, JM Whitelock
Biomaterials 32 (28), 6655-6662, 2011
1552011
Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis
JJ Zoeller, JM Whitelock, RV Iozzo
Matrix Biology 28 (5), 284-291, 2009
1472009
Structural and functional characterisation of poly (vinyl alcohol) and heparin hydrogels
A Nilasaroya, LA Poole-Warren, JM Whitelock, PJ Martens
Biomaterials 29 (35), 4658-4664, 2008
1412008
Interleukin-1 beta and transforming growth factor-alpha/epidermal growth factor induce expression of M (r) 95,000 type IV collagenase/gelatinase and interstitial fibroblast …
JG Lyons, B Birkedal-Hansen, MC Pierson, JM Whitelock, ...
Journal of Biological Chemistry 268 (25), 19143-19151, 1993
1411993
The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response
MS Lord, BG Cousins, PJ Doherty, JM Whitelock, A Simmons, RL Williams, ...
Biomaterials 27 (28), 4856-4862, 2006
1382006
Cancer metastasis: the role of the extracellular matrix and the heparan sulfate proteoglycan perlecan
Z Elgundi, M Papanicolaou, G Major, TR Cox, J Melrose, JM Whitelock, ...
Frontiers in oncology 9, 1482, 2020
1372020
The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
MS Lord, CY Chuang, J Melrose, MJ Davies, RV Iozzo, JM Whitelock
Matrix Biology 35, 112-122, 2014
1362014
A central function for perlecan in skeletal muscle and cardiovascular development
JJ Zoeller, A McQuillan, J Whitelock, SY Ho, RV Iozzo
The Journal of cell biology 181 (2), 381-394, 2008
1352008
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