Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research DGAJ Hebels, P Georgiadis, HC Keun, TJ Athersuch, P Vineis, ... Environmental health perspectives 121 (4), 480-487, 2013 | 149 | 2013 |
DNA methylation and exposure to ambient air pollution in two prospective cohorts M Plusquin, F Guida, S Polidoro, R Vermeulen, O Raaschou-Nielsen, ... Environment international 108, 127-136, 2017 | 108 | 2017 |
Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation YCM Staal, DGAJ Hebels, MHM van Herwijnen, RWH Gottschalk, ... Carcinogenesis 28 (12), 2632-2640, 2007 | 97 | 2007 |
Radical mechanisms in nitrosamine-and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells DGAJ Hebels, JJ Briedé, R Khampang, JCS Kleinjans, TMCM de Kok Toxicological sciences 116 (1), 194-205, 2010 | 62 | 2010 |
Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis DGAJ Hebels, DGJ Jennen, JCS Kleinjans, TMCM de Kok Toxicological sciences 108 (2), 290-300, 2009 | 49 | 2009 |
MicroRNA profile for health risk assessment: Environmental exposure to persistent organic pollutants strongly affects the human blood microRNA machinery J Krauskopf, TM de Kok, DG Hebels, IA Bergdahl, A Johansson, F Spaeth, ... Scientific reports 7 (1), 9262, 2017 | 48 | 2017 |
Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon DGAJ Hebels, KM Sveje, MC de Kok, MHM van Herwijnen, GGC Kuhnle, ... Food and Chemical Toxicology 50 (2), 95-103, 2012 | 48 | 2012 |
Prediagnostic transcriptomic markers of Chronic lymphocytic leukemia reveal perturbations 10 years before diagnosis M Chadeau-Hyam, RCH Vermeulen, D Hebels, R Castagné, ... Annals of oncology 25 (5), 1065-1072, 2014 | 43 | 2014 |
Linking the transcriptional landscape of bone induction to biomaterial design parameters N Groen, H Yuan, DGAJ Hebels, G Koçer, F Mbuyi, V LaPointe, ... Advanced materials 29 (10), 1603259, 2017 | 40 | 2017 |
Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking P Georgiadis, DG Hebels, I Valavanis, I Liampa, IA Bergdahl, ... Scientific reports 6 (1), 1-15, 2016 | 36 | 2016 |
N-nitroso compound exposure-associated transcriptomic profiles are indicative of an increased risk for colorectal cancer DGAJ Hebels, KM Sveje, MC de Kok, MHM van Herwijnen, GGC Kuhnle, ... Cancer letters 309 (1), 1-10, 2011 | 36 | 2011 |
Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns NRM Beijer, ZM Nauryzgaliyeva, EM Arteaga, L Pieuchot, K Anselme, ... Scientific reports 9 (1), 1-14, 2019 | 35 | 2019 |
diXa: a data infrastructure for chemical safety assessment DM Hendrickx, HJWL Aerts, F Caiment, D Clark, TMD Ebbels, CT Evelo, ... Bioinformatics 31 (9), 1505-1507, 2015 | 32 | 2015 |
Whole-genome gene expression modifications associated with nitrosamine exposure and micronucleus frequency in human blood cells DGAJ Hebels, DGJ Jennen, MHM van Herwijnen, EJC Moonen, ... Mutagenesis 26 (6), 753-761, 2011 | 28 | 2011 |
Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases A Chatziioannou, P Georgiadis, DG Hebels, I Liampa, I Valavanis, ... Scientific reports 7 (1), 1-13, 2017 | 27 | 2017 |
cBiT: A transcriptomics database for innovative biomaterial engineering DGAJ Hebels, A Carlier, MLJ Coonen, DH Theunissen, J de Boer Biomaterials 149, 88-97, 2017 | 26 | 2017 |
ToxDB: pathway-level interpretation of drug-treatment data C Hardt, ME Beber, A Rasche, A Kamburov, DG Hebels, JC Kleinjans, ... Database 2016, 2016 | 25 | 2016 |
Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis P Georgiadis, I Liampa, DG Hebels, J Krauskopf, A Chatziioannou, ... BMC genomics 18 (1), 1-15, 2017 | 21 | 2017 |
Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells S Vermeulen, N Roumans, F Honig, A Carlier, DGAJ Hebels, AD Eren, ... Biomaterials 259, 120331, 2020 | 20 | 2020 |
Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity DGA Hebels, MJA Jetten, HJW Aerts, R Herwig, DHJ Theunissen, S Gaj, ... Biomarkers in Medicine 8 (2), 185-200, 2014 | 19 | 2014 |