Rho GTPases and signaling networks L Van Aelst, C D’Souza-Schorey Genes & development 11 (18), 2295-2322, 1997 | 3133 | 1997 |
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling AW Lin, M Barradas, JC Stone, L Van Aelst, M Serrano, SW Lowe Genes & development 12 (19), 3008-3019, 1998 | 1190 | 1998 |
The role of the Rho GTPases in neuronal development EE Govek, SE Newey, L Van Aelst Genes & development 19 (1), 1-49, 2005 | 1174 | 2005 |
Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2 P Chardin, JH Camonis, NW Gale, L Van Aelst, J Schlessinger, MH Wigler, ... Science 260 (5112), 1338-1343, 1993 | 1097 | 1993 |
Ras and Rap control AMPA receptor trafficking during synaptic plasticity JJ Zhu, Y Qin, M Zhao, L Van Aelst, R Malinow Cell 110 (4), 443-455, 2002 | 927 | 2002 |
Complex formation between RAS and RAF and other protein kinases. L Van Aelst, M Barr, S Marcus, A Polverino, M Wigler Proceedings of the National Academy of Sciences 90 (13), 6213-6217, 1993 | 862 | 1993 |
Multiple Ras functions can contribute to mammalian cell transformation MA White, C Nicolette, A Minden, A Polverino, L Van Aelst, M Karin, ... Cell 80 (4), 533-541, 1995 | 835 | 1995 |
Rho GTPases: signaling, migration, and invasion AAP Schmitz, EE Govek, B Böttner, L Van Aelst Experimental cell research 261 (1), 1-12, 2000 | 790 | 2000 |
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration TL Gumienny, E Brugnera, AC Tosello-Trampont, JM Kinchen, LB Haney, ... Cell 107 (1), 27-41, 2001 | 670 | 2001 |
Connecting copper and cancer: from transition metal signalling to metalloplasia EJ Ge, AI Bush, A Casini, PA Cobine, JR Cross, GM DeNicola, QP Dou, ... Nature Reviews Cancer 22 (2), 102-113, 2022 | 642 | 2022 |
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways JK Westwick, QT Lambert, GJ Clark, M Symons, L Van Aelst, RG Pestell, ... Molecular and cellular biology, 1997 | 576 | 1997 |
The paraventricular thalamus controls a central amygdala fear circuit MA Penzo, V Robert, J Tucciarone, D De Bundel, M Wang, L Van Aelst, ... Nature 519 (7544), 455-459, 2015 | 467 | 2015 |
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation R Khosravi-Far, MA White, JK Westwick, PA Solski, ... Molecular and cellular biology, 1996 | 442 | 1996 |
Rho GTPases, dendritic structure, and mental retardation SE Newey, V Velamoor, EE Govek, L Van Aelst Journal of neurobiology 64 (1), 58-74, 2005 | 425 | 2005 |
A novel regulator of p21-activated kinases S Bagrodia, SJ Taylor, KA Jordon, L Van Aelst, RA Cerione Journal of Biological Chemistry 273 (37), 23633-23636, 1998 | 404 | 1998 |
Lck regulates Vav activation of members of the Rho family of GTPases J Han, B Das, W Wei, L Van Aelst, RD Mosteller, R Khosravi-Far, ... Molecular and cellular biology 17 (3), 1346-1353, 1997 | 398 | 1997 |
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis EE Govek, SE Newey, CJ Akerman, JR Cross, L Van der Veken, ... Nature neuroscience 7 (4), 364-372, 2004 | 368 | 2004 |
Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo Z Li, L Van Aelst, HT Cline Nature neuroscience 3 (3), 217-225, 2000 | 359 | 2000 |
RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase T Joneson, M McDonough, D Bar-Sagi, L Van Aelst Science 274 (5291), 1374-1376, 1996 | 346 | 1996 |
The role of Rho GTPases in disease development B Boettner, L Van Aelst Gene 286 (2), 155-174, 2002 | 337 | 2002 |