Modulation of anxiety through blockade of anandamide hydrolysis S Kathuria, S Gaetani, D Fegley, F Valiño, A Duranti, A Tontini, M Mor, ... Nature medicine 9 (1), 76-81, 2003 | 1683 | 2003 |
An endocannabinoid mechanism for stress-induced analgesia AG Hohmann, RL Suplita, NM Bolton, MH Neely, D Fegley, R Mangieri, ... Nature 435 (7045), 1108-1112, 2005 | 885 | 2005 |
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis G Gobbi, FR Bambico, R Mangieri, M Bortolato, P Campolongo, M Solinas, ... Proceedings of the National Academy of Sciences 102 (51), 18620-18625, 2005 | 794 | 2005 |
Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3′-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide … D Fegley, S Gaetani, A Duranti, A Tontini, M Mor, G Tarzia, D Piomelli Journal of Pharmacology and Experimental Therapeutics 313 (1), 352-358, 2005 | 495 | 2005 |
Pharmacological profile of the selective FAAH inhibitor KDS‐4103 (URB597) D Piomelli, G Tarzia, A Duranti, A Tontini, M Mor, TR Compton, O Dasse, ... CNS drug reviews 12 (1), 21-38, 2006 | 445 | 2006 |
Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress M Bortolato, RA Mangieri, J Fu, JH Kim, O Arguello, A Duranti, A Tontini, ... Biological psychiatry 62 (10), 1103-1110, 2007 | 403 | 2007 |
Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism JR Clapper, G Moreno-Sanz, R Russo, A Guijarro, F Vacondio, A Duranti, ... Nature neuroscience 13 (10), 1265-1270, 2010 | 392 | 2010 |
Cyclohexylcarbamic acid 3 ‘-or 4 ‘-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure− activity relationships, and … M Mor, S Rivara, A Lodola, PV Plazzi, G Tarzia, A Duranti, A Tontini, ... Journal of medicinal chemistry 47 (21), 4998-5008, 2004 | 337 | 2004 |
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus JK Makara, M Mor, D Fegley, SI Szabó, S Kathuria, G Astarita, A Duranti, ... Nature neuroscience 8 (9), 1139-1141, 2005 | 274 | 2005 |
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation C Solorzano, C Zhu, N Battista, G Astarita, A Lodola, S Rivara, M Mor, ... Proceedings of the National Academy of Sciences 106 (49), 20966-20971, 2009 | 266 | 2009 |
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3′-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice R Russo, J LoVerme, G La Rana, TR Compton, J Parrott, A Duranti, ... Journal of Pharmacology and Experimental Therapeutics 322 (1), 236-242, 2007 | 211 | 2007 |
Design, synthesis, and structure− activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors G Tarzia, A Duranti, A Tontini, G Piersanti, M Mor, S Rivara, PV Plazzi, ... Journal of medicinal chemistry 46 (12), 2352-2360, 2003 | 210 | 2003 |
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice J LoVerme, A Duranti, A Tontini, G Spadoni, M Mor, S Rivara, N Stella, ... Bioorganic & medicinal chemistry letters 19 (3), 639-643, 2009 | 135 | 2009 |
URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices AR King, A Duranti, A Tontini, S Rivara, A Rosengarth, JR Clapper, ... Chemistry & biology 14 (12), 1357-1365, 2007 | 128 | 2007 |
Endocannabinoids in the treatment of mood disorders: evidence from animal models F Rodriguez Bambico, A Duranti, A Tontini, G Tarzia, G Gobbi Current Pharmaceutical Design 15 (14), 1623-1646, 2009 | 120 | 2009 |
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat A Cippitelli, N Cannella, S Braconi, A Duranti, A Tontini, A Bilbao, ... Psychopharmacology 198 (4), 449-460, 2008 | 119 | 2008 |
Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models O Sasso, G Moreno-Sanz, C Martucci, N Realini, M Dionisi, L Mengatto, ... Pain 154 (3), 350-360, 2013 | 106 | 2013 |
2-Substituted 5-methoxy-N-acyltryptamines: synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity G Spadoni, B Stankov, A Duranti, G Biella, V Lucini, A Salvatori, ... | 93 | 1993 |
A Second Generation of Carbamate‐Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo JR Clapper, F Vacondio, AR King, A Duranti, A Tontini, C Silva, ... ChemMedChem 4 (9), 1505-1513, 2009 | 91 | 2009 |
Lactose oleate as new biocompatible surfactant for pharmaceutical applications DR Perinelli, S Lucarini, L Fagioli, R Campana, D Vllasaliu, A Duranti, ... European Journal of Pharmaceutics and Biopharmaceutics 124, 55-62, 2018 | 86 | 2018 |