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Florina Scurtu
Florina Scurtu
Researcher at University of Agricutural Sciences and Veterinary Medicine, Cluj-Napoca
Adresse e-mail validée de usamvcluj.ro
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Oxidative protection of hemoglobin and hemerythrin by cross-linking with a nonheme iron peroxidase: potentially improved oxygen carriers for use in blood substitutes
D Hathazi, AC Mot, A Vaida, F Scurtu, I Lupan, E Fischer-Fodor, ...
Biomacromolecules 15 (5), 1920-1927, 2014
402014
Nitrite binding to globins: linkage isomerism, EPR silence and reductive chemistry
R Silaghi-Dumitrescu, DA Svistunenko, D Cioloboc, C Bischin, F Scurtu, ...
Nitric Oxide 42, 32-39, 2014
282014
Towards hemerythrin-based blood substitutes: Comparative performance to hemoglobin on human leukocytes and umbilical vein endothelial cells
E Fischer-Fodor, A Mot, F Deac, M Arkosi, R Silaghi-Dumitrescu
Journal of Biosciences 36, 215-221, 2011
282011
The reaction of oxy hemoglobin with nitrite: Mechanism, antioxidant-modulated effect, and implications for blood substitute evaluation
D Hathazi, F Scurtu, C Bischin, A Mot, AAA Attia, J Kongsted, ...
Molecules 23 (2), 350, 2018
262018
Comparative In Vivo Effects of Hemoglobin-Based Oxygen Carriers (HBOC) with Varying Prooxidant and Physiological Reactivity
VA Toma, AD Farcaș, I Roman, B Sevastre, D Hathazi, F Scurtu, ...
PLoS One 11 (4), e0153909, 2016
232016
Hemoglobin–albumin cross-linking with disuccinimidyl suberate (DSS) and/or glutaraldehyde for blood substitutes
F Scurtu, O Zolog, B Iacob, R Silaghi-Dumitrescu
Artificial Cells, Nanomedicine, and Biotechnology 42 (1), 13-17, 2014
222014
Derivatization of haemoglobin with periodate-generated reticulation agents: evaluation of oxidative reactivity for potential blood substitutes
F Deac, B Iacob, E Fischer-Fodor, G Damian, R Silaghi-Dumitrescu
The journal of biochemistry 149 (1), 75-82, 2011
202011
Ascorbate peroxidase activity of cytochrome c
C Bischin, F Deac, R Silaghi-Dumitrescu, JAR Worrall, BS Rajagopal, ...
Free Radical Research 45 (4), 439-444, 2011
192011
Protein-based blood substitutes: recent attempts at controlling pro-oxidant reactivity with and beyond hemoglobin
VF Scurtu, AC Moţ, R Silaghi-Dumitrescu
Pharmaceuticals 6 (7), 867-880, 2013
172013
Hemoglobin-albumin crosslinked copolymers: reduced prooxidant reactivity
B Iacob, F Deac, D Cioloboc, G Damian, R Silaghi-Dumitrescu
Artificial Cells, Blood Substitutes, and Biotechnology 39 (5), 293-297, 2011
172011
A new polyethyleneglycol-derivatized hemoglobin derivative with decreased oxygen affinity and limited toxicity
O Zolog, A Mot, F Deac, A Roman, E Fischer-Fodor, R Silaghi-Dumitrescu
The Protein Journal 30, 27-31, 2011
172011
The high affinity of small-molecule antioxidants for hemoglobin
C Puscas, L Radu, F Carrascoza, AC Mot, D Amariei, O Lungu, F Scurtu, ...
Free Radical Biology and Medicine 124, 260-274, 2018
162018
Stability of glutaraldehyde in biocide compositions
A Matei, C Puscas, I Patrascu, M Lehene, J Ziebro, F Scurtu, M Baia, ...
International journal of molecular sciences 21 (9), 3372, 2020
142020
Ascorbate binding to globins
FV Deac, A Todea, AM Bolfa, P Podea, P Petrar, R Silaghi-Dumitrescu
Rom. J. Biochem 46, 115-121, 2009
142009
In vivo evaluation of hemerythrin-based oxygen carriers: Similarities with hemoglobin-based counterparts
VA Toma, AD Farcas, I Roman, B Sevastre, D Hathazi, F Scurtu, ...
International journal of biological macromolecules 107, 1422-1427, 2018
132018
Copolymerization of recombinant Phascolopsis gouldii hemerythrin with human serum albumin for use in blood substitutes
M Arkosi, F Scurtu, A Vulpoi, R Silaghi-Dumitrescu, D Kurtz Jr
Artificial Cells, Nanomedicine, and Biotechnology 45 (2), 218-223, 2017
122017
Involvement of ferryl in the reaction between nitrite and the oxy forms of globins
D Hathazi, SD Mahuţ, FV Scurtu, C Bischin, C Stanciu, AA Attia, G Damian, ...
JBIC Journal of Biological Inorganic Chemistry 19, 1233-1239, 2014
112014
Excess ascorbate is a chemical stress agent against proteins and cells
M Lehene, E Fischer-Fodor, F Scurtu, ND Hădade, E Gal, AC Mot, A Matei, ...
Pharmaceuticals 13 (6), 107, 2020
102020
Hemoglobin-based blood substitutes: which hemoglobin to use?
FV Deac, AM Bolfa, C Magdas, B Sevastre, S Turc, R Silaghi-Dumitrescu
82010
Glutaraldehyde-polymerized hemoglobin: in search of improved performance as oxygen carrier in hemorrhage models
AD Farcas, VA Toma, I Roman, B Sevastre, F Scurtu, ...
Bioinorganic Chemistry and Applications 2020, 2020
72020
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