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Aleks Nivina
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Year
The integron: adaptation on demand
JA Escudero, C Loot, A Nivina, D Mazel
Microbiology spectrum 3 (2), 10.1128/microbiolspec. mdna3-0019-2014, 2015
2082015
Evolution and diversity of assembly-line polyketide synthases: focus review
A Nivina, KP Yuet, J Hsu, C Khosla
Chemical reviews 119 (24), 12524-12547, 2019
2052019
Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites
A Nivina, JA Escudero, C Vit, D Mazel, C Loot
Nucleic acids research 44 (16), 7792-7803, 2016
542016
Engineering of chimeric polyketide synthases using SYNZIP docking domains
M Klaus, AD D’Souza, A Nivina, C Khosla, M Grininger
ACS chemical biology 14 (3), 426-433, 2019
352019
Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
JA Escudero, C Loot, V Parissi, A Nivina, C Bouchier, D Mazel
Nature communications 7 (1), 10937, 2016
352016
Differences in integron cassette excision dynamics shape a trade-off between evolvability and genetic capacitance
C Loot, A Nivina, J Cury, JA Escudero, M Ducos-Galand, D Bikard, ...
MBio 8 (2), 10.1128/mbio. 02296-16, 2017
302017
Dynamic stepwise opening of integron attC DNA hairpins by SSB prevents toxicity and ensures functionality
MS Grieb, A Nivina, BL Cheeseman, A Hartmann, D Mazel, M Schlierf
Nucleic acids research 45 (18), 10555-10563, 2017
292017
Structural heterogeneity of attC integron recombination sites revealed by optical tweezers
A Mukhortava, M Pöge, MS Grieb, A Nivina, C Loot, D Mazel, M Schlierf
Nucleic acids research 47 (4), 1861-1870, 2019
212019
Structure-specific DNA recombination sites: Design, validation, and machine learning–based refinement
A Nivina, MS Grieb, C Loot, D Bikard, J Cury, L Shehata, J Bernardes, ...
Science advances 6 (30), eaay2922, 2020
182020
GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification
A Nivina, S Herrera Paredes, HB Fraser, C Khosla
Proceedings of the National Academy of Sciences 118 (26), e2100751118, 2021
142021
Integron identification in bacterial genomes and cassette recombination assays
C Vit, C Loot, JA Escudero, A Nivina, D Mazel
Horizontal Gene Transfer: Methods and Protocols, 189-208, 2020
82020
Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions
JA Escudero, A Nivina, HE Kemble, C Loot, O Tenaillon, D Mazel
Elife 9, e58061, 2020
62020
Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation
JA Escudero, A Nivina, G Cambray, R López‐Igual, C Loot, D Mazel
Biotechnology and Bioengineering 115 (1), 184-191, 2018
52018
The Integron: Adaptation On Demand. Microbiol. Spectr. 2015, 3
JA Escudero, C Loot, A Nivina, D Mazel
MDNA3-0019-2014.[CrossRef][PubMed], 0
5
Identification of polyketide biosynthetic gene clusters that harbor self-resistance target genes
GA Vandova, A Nivina, C Khosla, RW Davis, CR Fisher, ME Hillenmeyer
BioRxiv, 2020.06. 01.128595, 2020
32020
Synthetic attc recombination sites for protein domain shuffling
D Mazel, A Nivina, D Bikard, MS Grieb
US Patent App. 16/316,476, 2020
2020
DNA Secondary Structure Formation in Bacterial Gene Capture Systems at Single-Molecule Resolution
M Swoboda, MS Grieb, V Natarajan, A Nivina, D Mazel, M Schlierf
Biophysical Journal 106 (2), 272a-273a, 2014
2014
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