George Simos
George Simos
Professor of Biochemistry, Faculty of Medicine, University of Thessaly, Larissa, Greece
Adresă de e-mail confirmată pe med.uth.gr - Pagina de pornire
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Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1α
I Mylonis, G Chachami, M Samiotaki, G Panayotou, E Paraskeva, ...
Journal of Biological Chemistry 281 (44), 33095-33106, 2006
Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores
H Santos-Rosa, H Moreno, G Simos, A Segref, B Fahrenkrog, N Panté, ...
Molecular and cellular biology 18 (11), 6826-6838, 1998
Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA
K Hellmuth, DM Lau, FR Bischoff, M Künzler, ED Hurt, G Simos
Molecular and cellular biology, 1998
The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl‐and glutamyl‐tRNA synthetases.
G Simos, A Segref, F Fasiolo, K Hellmuth, A Shevchenko, M Mann, ...
The EMBO journal 15 (19), 5437-5448, 1996
Hypoxia-Inducible Factors and the Regulation of Lipid Metabolism
I Mylonis, G Simos, E Paraskeva
Cells 8 (3), 214, 2019
Mtr10p functions as a nuclear import receptor for the mRNA‐binding protein Npl3p
B Senger, G Simos, FR Bischoff, A Podtelejnikov, M Mann, E Hurt
The EMBO journal, 1998
An aminoacylation-dependent nuclear tRNA export pathway in yeast
H Grosshans, E Hurt, G Simos
Genes & development 14 (7), 830-840, 2000
A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants
E Hurt, S Hannus, B Schmelzl, D Lau, D Tollervey, G Simos
The Journal of cell biology 144 (3), 389-401, 1999
Nuclear pore proteins are involved in the biogenesis of functional tRNA.
G Simos, H Tekotte, H Grosjean, A Segref, K Sharma, D Tollervey, ...
The EMBO Journal 15 (9), 2270-2284, 1996
The lamin B receptor (LBR) provides essential chromatin docking sites at the nuclear envelope.
A Pyrpasopoulou, J Meier, C Maison, G Simos, SD Georgatos
The EMBO Journal 15 (24), 7108-7119, 1996
Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression
I Mylonis, H Sembongi, C Befani, P Liakos, S Siniossoglou, G Simos
J Cell Sci 125 (14), 3485-3493, 2012
Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export
H Grosshans, K Deinert, E Hurt, G Simos
The Journal of cell biology 153 (4), 745-762, 2001
Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of Ψ38 and Ψ39 in tRNA anticodon loop
F Lecointe, G Simos, A Sauer, EC Hurt, Y Motorin, H Grosjean
Journal of Biological Chemistry 273 (3), 1316-1323, 1998
A conserved domain within Arc1p delivers tRNA to aminoacyl-tRNA synthetases
G Simos, A Sauer, F Fasiolo, EC Hurt
Molecular cell 1 (2), 235-242, 1998
Cobalt induces hypoxia-inducible factor-1α (HIF-1α) in HeLa cells by an iron-independent, but ROS-, PI-3K-and MAPK-dependent mechanism
A Triantafyllou, P Liakos, A Tsakalof, E Georgatsou, G Simos, S Bonanou
Free radical research 40 (8), 847-856, 2006
Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells
CD Befani, PJ Vlachostergios, E Hatzidaki, A Patrikidou, S Bonanou, ...
Journal of molecular medicine 90, 45-54, 2012
Atypical CRM1-dependent nuclear export signal mediates regulation of Hypoxia-inducible Factor-1α by MAPK
I Mylonis, G Chachami, E Paraskeva, G Simos
Journal of Biological Chemistry 283 (41), 27620-27627, 2008
The yeast tRNA: pseudouridine synthase Pus1p displays a multisite substrate specificity.
Y Motorin, G Keith, C Simon, D Foiret, G Simos, E Hurt, H Grosjean
Rna 4 (7), 856-869, 1998
The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions
I Mylonis, A Lakka, A Tsakalof, G Simos
Biochemical and biophysical research communications 398 (1), 74-78, 2010
Binding of lamin A to polynucleosomes.
J Yuan, G Simos, G Blobel, SD Georgatos
Journal of Biological Chemistry 266 (14), 9211-9215, 1991
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