The α/β hydrolase fold DL Ollis, E Cheah, M Cygler, B Dijkstra, F Frolow, SM Franken, M Harel, ... Protein Engineering, Design and Selection 5 (3), 197-211, 1992 | 2852 | 1992 |
Bacillus thuringiensisCrylA (a) insecticidal toxin: crystal structure and channel formation P Grochulski, L Masson, S Borisova, M Pusztai-Carey, JL Schwartz, ... Journal of molecular biology 254 (3), 447-464, 1995 | 799 | 1995 |
Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins M Cygler, JD Schrag, JL Sussman, M Harel, I Silman, MK Gentry, ... Protein Science 2 (3), 366-382, 1993 | 737 | 1993 |
Insights into interfacial activation from an open structure of Candida rugosa lipase P Grochulski, Y Li, JD Schrag, F Bouthillier, P Smith, D Harrison, B Rubin, ... Journal of Biological Chemistry 268 (17), 12843-12847, 1993 | 732 | 1993 |
Ser-His-Glu triad forms the catalytic site of the lipase from Geotrichum candidum JD Schrag, Y Li, S Wu, M Cygler Nature 351 (6329), 761-764, 1991 | 678 | 1991 |
The structure of calnexin, an ER chaperone involved in quality control of protein folding JD Schrag, JJM Bergeron, Y Li, S Borisova, M Hahn, DY Thomas, ... Molecular cell 8 (3), 633-644, 2001 | 509 | 2001 |
Two conformational states of Candida rugosa lipase P Grochulski, Y Li, JD Schrag, M Cygler Protein Science 3 (1), 82-91, 1994 | 490 | 1994 |
A structural basis for the chiral preferences of lipases M Cygler, P Grochulski, RJ Kazlauskas, JD Schrag, F Bouthillier, B Rubin, ... Journal of the American Chemical Society 116 (8), 3180-3186, 1994 | 467 | 1994 |
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment. R Coulombe, P Grochulski, J Sivaraman, R Menard, JS Mort, M Cygler The EMBO journal 15 (20), 5492-5503, 1996 | 462 | 1996 |
[4] Lipases and αβ hydrolase fold JD Schrag, M Cygler Methods in enzymology 284, 85-107, 1997 | 379 | 1997 |
The open conformation of a Pseudomonas lipase JD Schrag, Y Li, M Cygler, D Lang, T Burgdorf, HJ Hecht, R Schmid, ... Structure 5 (2), 187-202, 1997 | 375 | 1997 |
Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment M Cygler, DR Rose, DR Bundle Science 253 (5018), 442-445, 1991 | 344 | 1991 |
Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase P Grochulski, F Bouthillier, RJ Kazlauskas, AN Serreqi, JD Schrag, ... Biochemistry 33 (12), 3494-3500, 1994 | 331 | 1994 |
Structural and mechanistic classification of uronic acid-containing polysaccharide lyases ML Garron, M Cygler Glycobiology 20 (12), 1547-1573, 2010 | 318 | 2010 |
Structural basis for Fe–S cluster assembly and tRNA thiolation mediated by IscS protein–protein interactions R Shi, A Proteau, M Villarroya, I Moukadiri, L Zhang, JF Trempe, A Matte, ... PLoS biology 8 (4), e1000354, 2010 | 313 | 2010 |
Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes H Blanchard, P Grochulski, Y Li, JSC Arthur, PL Davies, JS Elce, M Cygler Nature Structural Biology 4 (7), 532-538, 1997 | 283 | 1997 |
Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution. A Zdanov, Y Li, DR Bundle, SJ Deng, CR MacKenzie, SA Narang, ... Proceedings of the National Academy of Sciences 91 (14), 6423-6427, 1994 | 243 | 1994 |
Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion M Cygler, J Sivaraman, P Grochulski, R Coulombe, AC Storer, JS Mort Structure 4 (4), 405-416, 1996 | 240 | 1996 |
Lectin control of protein folding and sorting in the secretory pathway JD Schrag, DO Procopio, M Cygler, DY Thomas, JJM Bergeron Trends in biochemical sciences 28 (1), 49-57, 2003 | 233 | 2003 |
The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering YG Kim, S Raunser, C Munger, J Wagner, YL Song, M Cygler, T Walz, ... Cell 127 (4), 817-830, 2006 | 208 | 2006 |