Three different spectrophotometric methods manipulating ratio spectra for determination of binary mixture of Amlodipine and Atorvastatin HW Darwish, SA Hassan, MY Salem, BA El-Zeiny Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 83 (1 …, 2011 | 130 | 2011 |
Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin AS Abdelhameed, AM Alanazi, AH Bakheit, HW Darwish, HA Ghabbour, ... Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 171, 174-182, 2017 | 76 | 2017 |
Three different methods for determination of binary mixture of amlodipine and atorvastatin using dual wavelength spectrophotometry HW Darwish, SA Hassan, MY Salem, BA El-Zeany Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 104, 70-76, 2013 | 73 | 2013 |
Comparative study between derivative spectrophotometry and multivariate calibration as analytical tools applied for the simultaneous quantitation of Amlodipine, Valsartan and … HW Darwish, SA Hassan, MY Salem, BA El-Zeany Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 113, 215-223, 2013 | 50 | 2013 |
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2 HM Alkahtani, AN Abdalla, AJ Obaidullah, MM Alanazi, AA Almehizia, ... Bioorganic Chemistry 95, 103461, 2020 | 48 | 2020 |
Different approaches in partial least squares and artificial neural network models applied for the analysis of a ternary mixture of amlodipine, valsartan and hydrochlorothiazide HW Darwish, SA Hassan, MY Salem, BA El-Zeany Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 122, 744-750, 2014 | 41 | 2014 |
Detection and characterization of ponatinib reactive metabolites by liquid chromatography tandem mass spectrometry and elucidation of bioactivation pathways AA Kadi, HW Darwish, MW Attwa, SM Amer RSC advances 6 (76), 72575-72585, 2016 | 40 | 2016 |
Investigation of metabolic degradation of new ALK inhibitor: Entrectinib by LC-MS/MS MW Attwa, HW Darwish, HA Alhazmi, AA Kadi Clinica Chimica Acta 485, 298-304, 2018 | 39 | 2018 |
Support vector regression and artificial neural network models for stability indicating analysis of mebeverine hydrochloride and sulpiride mixtures in pharmaceutical … IA Naguib, HW Darwish Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 86, 515-526, 2012 | 38 | 2012 |
Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC–ESI–MS/MS MW Attwa, AA Kadi, HW Darwish, SM Amer, NS Al-Shakliah Chemistry Central Journal 12, 1-16, 2018 | 37 | 2018 |
Identification and characterization of in vitro phase I and reactive metabolites of masitinib using a LC-MS/MS method: bioactivation pathway elucidation SM Amer, AA Kadi, HW Darwish, MW Attwa RSC advances 7 (8), 4479-4491, 2017 | 37 | 2017 |
LC–MS/MS reveals the formation of iminium and quinone methide reactive intermediates in entrectinib metabolism: in vivo and in vitro metabolic investigation MW Attwa, AA Kadi, H Alrabiah, HW Darwish Journal of pharmaceutical and biomedical analysis 160, 19-30, 2018 | 36 | 2018 |
Solid-state potentiometric sensor for the rapid assay of the biologically active biogenic amine (tyramine) as a marker of food spoilage ME Draz, HW Darwish, IA Darwish, AS Saad Food Chemistry 346, 128911, 2021 | 35 | 2021 |
LC–MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate SM Amer, AA Kadi, HW Darwish, MW Attwa Chemistry Central Journal 11, 1-7, 2017 | 33 | 2017 |
Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation SM Amer, AA Kadi, HW Darwish, MW Attwa Chemistry Central Journal 11, 1-8, 2017 | 33 | 2017 |
A reliable and stable method for the determination of foretinib in human plasma by LC-MS/MS: application to metabolic stability investigation and excretion rate MW Attwa, AA Kadi, HW Darwish, SM Amer, H Alrabiah European Journal of Mass Spectrometry 24 (4), 344-351, 2018 | 32 | 2018 |
LC-MS/MS reveals the formation of aldehydes and iminium reactive intermediates in foretinib metabolism: phase I metabolic profiling AA Kadi, SM Amer, HW Darwish, MW Attwa RSC advances 7 (58), 36279-36287, 2017 | 32 | 2017 |
A highly efficient and sensitive LC‐MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study AA Kadi, AS Abdelhameed, HW Darwish, MW Attwa, NS Al‐Shakliah Biomedical Chromatography 30 (8), 1248-1255, 2016 | 32 | 2016 |
Multivariate versus classical univariate calibration methods for spectrofluorimetric data: application to simultaneous determination of olmesartan medoxamil and amlodipine … HW Darwish, AH Backeit Journal of fluorescence 23, 79-91, 2013 | 31 | 2013 |
Investigation of the metabolic stability of olmutinib by validated LC-MS/MS: quantification in human plasma MW Attwa, AA Kadi, HW Darwish, AS Abdelhameed RSC advances 8 (70), 40387-40394, 2018 | 30 | 2018 |