Debbie McKenzie
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Mitochondrial DNA–deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers
E Bua, J Johnson, A Herbst, B Delong, D McKenzie, S Salamat, JM Aiken
The American Journal of Human Genetics 79 (3), 469-480, 2006
Prions adhere to soil minerals and remain infectious
CJ Johnson, KE Phillips, PT Schramm, D McKenzie, JM Aiken, ...
PLoS pathogens 2 (4), e32, 2006
Oral transmissibility of prion disease is enhanced by binding to soil particles
CJ Johnson, JA Pedersen, RJ Chappell, D McKenzie, JM Aiken
PLoS Pathogens 3 (7), e93, 2007
Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia
EA Bua, SH McKiernan, J Wanagat, D McKenzie, JM Aiken
Journal of applied physiology 92 (6), 2617-2624, 2002
Prion strain mutation determined by prion protein conformational compatibility and primary structure
RC Angers, HE Kang, D Napier, S Browning, T Seward, C Mathiason, ...
Science 328 (5982), 1154-1158, 2010
Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss
A Herbst, JW Pak, D McKenzie, E Bua, M Bassiouni, JM Aiken
The Journals of Gerontology Series A: Biological Sciences and Medical …, 2007
Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease
C Johnson, J Johnson, JP Vanderloo, D Keane, JM Aiken, D McKenzie
Journal of General Virology 87 (7), 2109-2114, 2006
Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy
JC Bartz, RA Bessen, D McKenzie, RF Marsh, JM Aiken
Journal of virology 74 (12), 5542-5547, 2000
The host range of chronic wasting disease is altered on passage in ferrets
JC Bartz, RF Marsh, DI McKenzie, JM Aiken
Virology 251 (2), 297-301, 1998
Reversibility of scrapie inactivation is enhanced by copper
D McKenzie, J Bartz, J Mirwald, D Olander, R Marsh, J Aiken
Journal of Biological Chemistry 273 (40), 25545-25547, 1998
Persistence and expression of Microplitis demolitor polydnavirus in Pseudoplusia includens
MR Strand, DI McKenzie, V Grassl, BA Dover, JM Aiken
Journal of General Virology 73 (7), 1627-1635, 1992
Prion protein polymorphisms affect chronic wasting disease progression
CJ Johnson, A Herbst, C Duque-Velasquez, JP Vanderloo, P Bochsler, ...
PLoS One 6 (3), e17450, 2011
Mitochondrial DNA deletion mutations: a causal role in sarcopenia
D McKenzie, E Bua, S McKiernan, Z Cao, Jonathan Wanagat, JM Aiken
European Journal of Biochemistry 269 (8), 2010-2015, 2002
Prion protein gene heterogeneity in free-ranging white-tailed deer within the chronic wasting disease affected region of Wisconsin
C Johnson, J Johnson, M Clayton, D McKenzie, J Aiken
Journal of wildlife diseases 39 (3), 576-581, 2003
Mitochondrial DNA mutations as a fundamental mechanism in physiological declines associated with aging
JW Pak, A Herbst, E Bua, N Gokey, D McKenzie, JM Aiken
Aging cell 2 (1), 1-7, 2003
Sarcopenia accelerates at advanced ages in Fisher 344× Brown Norway rats
EB Lushaj, JK Johnson, D McKenzie, JM Aiken
The Journals of Gerontology Series A: Biological Sciences and Medical …, 2008
Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys
NG Gokey, Z Cao, JW Pak, D Lee, SH McKiernan, D McKenzie, ...
Aging cell 3 (5), 319-326, 2004
Mitochondrial DNA deletion mutations and sarcopenia
J Aiken, E Bua, Z Cao, M Lopez, JON Wanagat, D McKENZIE, ...
Annals of the New York Academy of Sciences 959 (1), 412-423, 2002
Apoptosis and necrosis mediate skeletal muscle fiber loss in age‐induced mitochondrial enzymatic abnormalities
N Cheema, A Herbst, D McKenzie, JM Aiken
Aging cell 14 (6), 1085-1093, 2015
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints
EV Minikel, HT Zhao, J Le, J O’Moore, R Pitstick, S Graffam, GA Carlson, ...
Nucleic acids research 48 (19), 10615-10631, 2020
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